376. Lukasiewicz PD and Shields CR. (1998) Different combinations of GABAA and GABAC receptors confer distinct temporal properties to retinal synaptic responses. J Neurophysiol 79:3157-67 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Retina bipolar cellDistal equivalent dendriteGabahorizontal cell?The pharmacologically isolated, GABAergic synaptic currents in bipolar cells were long-lasting (compared with those in in ganglion cells, which are relatively brief). The GABAA receptor component of the bipolar cell response was relatively brief compared with the GABAC receptor component (Lukasiewicz PD and Shields CR, 1998376 ). In retinal bipolar cells of bullfrog, both axon terminals and dendrites showed high GABA sensitivity mediated by both GABA(A) and GABA(C) receptors. GABA(A) and GABA(C) receptors may play different roles in the outer and inner retina and the differential complements of the two receptors on OFF and ON BCs may be closely related to physiological functions of these cells (Du JL and Yang XL, 2000395 ). GABA(A) receptors mediate GABAergic inhibition on bipolar cell dendrites in the OPL, that GABA(A) and GABA(C) receptors mediate inhibition on axon terminals in the IPL, and that the GABA(C):GABA(A) on the terminals may tune the response characteristics of the bipolar cell (Shields CR et al, 2000396 ).

References
376. Lukasiewicz PD and Shields CR. (1998) Different combinations of GABAA and GABAC receptors confer distinct temporal properties to retinal synaptic responses. J Neurophysiol 79:3157-67 [Journal] .
395. Du JL and Yang XL. (2000) Subcellular localization and complements of GABA(A) and GABA(C) receptors on bullfrog retinal bipolar cells. J Neurophysiol 84:666-76 [Journal] .
396. Shields CR, Tran MN, Wong RO and Lukasiewicz PD. (2000) Distinct ionotropic GABA receptors mediate presynaptic and postsynaptic inhibition in retinal bipolar cells. J Neurosci 20:2673-82.
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