|Retina bipolar cell||Axon terminal||Gaba||.||GABA(A) and GABA(C) receptor-mediated currents were observed in the isolated terminal (Pan ZH, 2001374 ).
Isolated rod-dominant on-center bipolar cells respond to GABA, the highest sensitivity of which being located at the axon terminal (Tachibana M and Kaneko A, 1987386 ). Zn2+ modulates the inhibitory interaction between amacrine and bipolar cells, particularly that mediated by the GABA(C) receptor(Kaneda M et al, 2000387 ) In retinal bipolar cells of bullfrog, both axon terminals and dendrites showed high GABA sensitivity mediated by both GABA(A) and GABA(C) receptors. GABA(A) and GABA(C) receptors may play different roles in the outer and inner retina and the differential complements of the two receptors on OFF and ON BCs may be closely related to physiological functions of these cells (Du JL and Yang XL, 2000395 ). GABA(A) receptors mediate GABAergic inhibition on bipolar cell dendrites in the OPL, that GABA(A) and GABA(C) receptors mediate inhibition on axon terminals in the IPL, and that the GABA(C):GABA(A) on the terminals may tune the response characteristics of the bipolar cell (Shields CR et al, 2000396 ).