419. Slesinger PA, Stoffel M, Jan YN and Jan LY. (1997) Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Proc Natl Acad Sci U S A 94:12210-7.

NeuronCompartmentPropertyConnectivityNotes
Cerebellum interneuron granule cellSomaI Potassium.Granule cells that lack GABAA receptors (in somatic location? ) express the two-pore-domain K+ channel TASK-1, a voltage-independent K + conductance, so as to maintain normal neuronal behaviour (Brickley SG et al, 2001418 ). Importance for membrane excitability of an GABAB receptor-activated inward-rectifying potassium current, sensitive to pertussis toxin and barium (Slesinger PA et al, 1997419 ). Cerebellar granule cells from young rats (postnatal days 1-9) possess voltage-activated inward Na+ current as well as two types of K+ current, IA and IK (Cull-Candy SG et al, 1989430 ). Single-channel and whole-cell recording identified three types of current: a transient inward sodium current and a transient and a sustained outward potassium current (Jalonen T et al, 1990429 ).

References
418. Brickley SG, Revilla V, Cull-Candy SG, Wisden W and Farrant M. (2001) Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature 409:88-92.
419. Slesinger PA, Stoffel M, Jan YN and Jan LY. (1997) Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Proc Natl Acad Sci U S A 94:12210-7.
430. Cull-Candy SG, Marshall CG and Ogden D. (1989) Voltage-activated membrane currents in rat cerebellar granule neurones. J Physiol 414:179-99.
429. Jalonen T, Johansson S, Holopainen I, Oja SS and Arhem P. (1990) Single-channel and whole-cell currents in rat cerebellar granule cells. Brain Res 535:33-8.
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