42. Geffen LB, Jessell TM, Cuello AC and Iversen LL. (1976) Release of dopamine from dendrites in rat substantia nigra. Nature 260:258-60.

NeuronCompartmentPropertyConnectivityNotes
Substantia nigra pars compacta dopaminergic cellDistal apical dendriteDopamine-----DA is released from dendrites (Geffen LB et al, 1976 [rat ]42 ; Korf et al, 1976; Cheramy et al 1981) by backpropagating impulse (Hausser M et al, 1995 [rat ]40 ); acts on D2 autoreceptors (Lacey MG et al, 1987 [rat ]77 , 1990) causing hyperpolarization, and presynaptic GABAb receptors causing enhancement of synaptic inhibition (Cameron and Williams, 1993). (Reviewed in Hausser M et al, 1995 [rat ]40 ).
Substantia nigra pars compacta dopaminergic cellMiddle apical dendriteDopamine-----DA is released from dendrites (Geffen LB et al, 1976 [rat ]42 ; Korf et al, 1976; Cheramy et al 1981) by backpropagating impulse (Hausser M et al, 1995 [rat ]40 ); acts on D2 autoreceptors (Lacey MG et al, 1987 [rat ]77 , 1990) causing hyperpolarization, and presynaptic GABAb receptors causing enhancement of synaptic inhibition (Cameron and Williams, 1993). (Reviewed in Hausser M et al, 1995 [rat ]40 ).
Substantia nigra pars compacta dopaminergic cellMiddle apical dendriteI p,q.The action potential has a pronounced Ca component on its falling phase (Yung WH et al, 1991 [guinea pig ]41 ; reviewed in Hausser M et al, 1995 [rat ]40 ).Yung WH et al, 1991 [guinea pig ]41 , Geffen LB et al, 1976 [rat ]42 , Stuart GJ and Sakmann B, 1994 [rat ]43
Substantia nigra pars compacta dopaminergic cellProximal apical dendriteDopamine-----DA is released from dendrites (Geffen LB et al, 1976 [rat ]42 ; Korf et al, 1976; Cheramy et al 1981) by backpropagating impulse (Hausser M et al, 1995 [rat ]40 ); acts on D2 autoreceptors (Lacey MG et al, 1987 [rat ]77 , 1990) causing hyperpolarization, and presynaptic GABAb receptors causing enhancement of synaptic inhibition (Cameron and Williams, 1993). (Reviewed in Hausser M et al, 1995 [rat ]40 ).

References
42. Geffen LB, Jessell TM, Cuello AC and Iversen LL. (1976) Release of dopamine from dendrites in rat substantia nigra. Nature 260:258-60.
40. Hausser M, Stuart G, Racca C and Sakmann B. (1995) Axonal initiation and active dendritic propagation of action potentials in substantia nigra neurons. Neuron 15:637-47.
77. Lacey MG, Mercuri NB and North RA. (1987) Dopamine acts on D2 receptors to increase potassium conductance in neurones of the rat substantia nigra zona compacta. J Physiol 392:397-416.
41. Yung WH, Hausser MA and Jack JJ. (1991) Electrophysiology of dopaminergic and non-dopaminergic neurones of the guinea-pig substantia nigra pars compacta in vitro. J Physiol 436:643-67.
43. Stuart GJ and Sakmann B. (1994) Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 367:69-72.
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