420. Casado M, Isope P and Ascher P. (2002) Involvement of presynaptic N-methyl-D-aspartate receptors in cerebellar long-term depression. Neuron 33:123-30.

NeuronCompartmentPropertyConnectivityNotes
Cerebellum interneuron granule cellAxon terminalNMDA.Involvement of presynaptic NMDA receptors in cerebellar long-term depression at parallel fiber-Purkinje cell synapses (Casado M et al, 2002420 ). NMDA reversibly depresses postsynaptic currents, through a trans-synaptic mechanism that involves release from parallel fibers nitric oxide that decreases the glutamate sensitivity of the Purkinje cell (Casado M et al, 2000422 ).

References
420. Casado M, Isope P and Ascher P. (2002) Involvement of presynaptic N-methyl-D-aspartate receptors in cerebellar long-term depression. Neuron 33:123-30.
422. Casado M, Dieudonne S and Ascher P. (2000) Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse. Proc Natl Acad Sci U S A 97:11593-7.
_7/18/2018 10:06:49 AM