462. Debarbieux F, Audinat E and Charpak S. (2003) Action potential propagation in dendrites of rat mitral cells in vivo. J Neurosci 23:5553-60.

NeuronCompartmentPropertyConnectivityNotes
Olfactory bulb main mitral cellProximal basal dendriteI Na,t.Dual patch recordings and Ca2+ imaging of mitral cells in the rat olfactory bulb slice suggested that action potentials propagating into the basal dendrites decrement approximately 20% per 100um (Margrie TW et al, 2001293 ). Using Ca2+ imaging, full action potential invasion throughout the length of the basal dendrites, suggesting the presence of Na channels at somatic density, was observed by Xiong W and Chen WR, 2002 [rat ]398 . By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches (Debarbieux F et al, 2003462 ).
Olfactory bulb main mitral cellDistal apical dendriteI Na,t.Implied by recording of fast prepotential. Dual patch recordings provide evidence for both backpropagating and forward-propagating impulses in the primary dendrite (Mori K et al, 1982 [turtle ]19 ; Chen et al 1997). Dendritic patch recordings showed an even density of Na channels (120pS um-2) up to 350 um from the soma along the primary dendrite to the origin of the glomerular tuft (Bischofberger J and Jonas P, 1997397 ). By combining intracellular recordings and two-photon microscopy imaging of [Ca]i in rat it was shown that APs backpropagate at full amplitude up to the tuft (Debarbieux F et al, 2003462 ).
Olfactory bulb main mitral cellDistal basal dendriteI Na,t.Dual patch recordings and Ca2+ imaging of mitral cells in the rat olfactory bulb slice suggested that action potentials propagating into the basal dendrites decrement approximately 20% per 100um (Margrie TW et al, 2001293 ). Using Ca2+ imaging, full action potential invasion throughout the length of the basal dendrites, suggesting the presence of Na channels at somatic density, was observed by Xiong W and Chen WR, 2002 [rat ]398 . By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches (Debarbieux F et al, 2003462 ).
Olfactory bulb main mitral cellMiddle basal dendriteI Na,t.Dual patch recordings and Ca2+ imaging of mitral cells in the rat olfactory bulb slice suggested that action potentials propagating into the basal dendrites decrement approximately 20% per 100um (Margrie TW et al, 2001293 ). Using Ca2+ imaging, full action potential invasion throughout the length of the basal dendrites, suggesting the presence of Na channels at somatic density, was observed by Xiong W and Chen WR, 2002 [rat ]398 . By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches (Debarbieux F et al, 2003462 ).
Olfactory bulb main tufted middle cellDistal apical dendriteI Na,t.Implied by recording of fast prepotential. Dual patch recordings provide evidence for both backpropagating and forward-propagating impulses in the primary dendrite (Mori K et al, 1982 [turtle ]19 ; Chen et al 1997). Dendritic patch recordings showed an even density of Na channels (120pS um-2) up to 350 um from the soma along the primary dendrite to the origin of the glomerular tuft (Bischofberger J and Jonas P, 1997397 ). By combining intracellular recordings and two-photon microscopy imaging of [Ca]i in rat it was shown that APs backpropagate at full amplitude up to the tuft (Debarbieux F et al, 2003462 ).
Olfactory bulb main tufted middle cellDistal basal dendriteI Na,t.Dual patch recordings and Ca2+ imaging of mitral cells in the rat olfactory bulb slice suggested that action potentials propagating into the basal dendrites decrement approximately 20% per 100um (Margrie TW et al, 2001293 ). Using Ca2+ imaging, full action potential invasion throughout the length of the basal dendrites, suggesting the presence of Na channels at somatic density, was observed by Xiong W and Chen WR, 2002 [rat ]398 . By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches (Debarbieux F et al, 2003462 ).
Olfactory bulb main tufted middle cellMiddle basal dendriteI Na,t.Dual patch recordings and Ca2+ imaging of mitral cells in the rat olfactory bulb slice suggested that action potentials propagating into the basal dendrites decrement approximately 20% per 100um (Margrie TW et al, 2001293 ). Using Ca2+ imaging, full action potential invasion throughout the length of the basal dendrites, suggesting the presence of Na channels at somatic density, was observed by Xiong W and Chen WR, 2002 [rat ]398 . By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches (Debarbieux F et al, 2003462 ).
Olfactory bulb main tufted middle cellProximal basal dendriteI Na,t.Dual patch recordings and Ca2+ imaging of mitral cells in the rat olfactory bulb slice suggested that action potentials propagating into the basal dendrites decrement approximately 20% per 100um (Margrie TW et al, 2001293 ). Using Ca2+ imaging, full action potential invasion throughout the length of the basal dendrites, suggesting the presence of Na channels at somatic density, was observed by Xiong W and Chen WR, 2002 [rat ]398 . By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches (Debarbieux F et al, 2003462 ).

References
293. Margrie TW, Sakmann B and Urban NN. (2001) Action potential propagation in mitral cell lateral dendrites is decremental and controls recurrent and lateral inhibition in the mammalian olfactory bulb. Proc Natl Acad Sci U S A 98:319-24.
398. Xiong W and Chen WR. (2002) Dynamic gating of spike propagation in the mitral cell lateral dendrites. Neuron 34:115-26.
462. Debarbieux F, Audinat E and Charpak S. (2003) Action potential propagation in dendrites of rat mitral cells in vivo. J Neurosci 23:5553-60.
19. Mori K, Nowycky MC and Shepherd GM. (1982) Impulse activity in presynaptic dendrites: analysis of mitral cells in the isolated turtle olfactory bulb. J Neurosci 2:497-502.
397. Bischofberger J and Jonas P. (1997) Action potential propagation into the presynaptic dendrites of rat mitral cells. J Physiol 504 ( Pt 2):359-65.
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