583. Deniau JM, Mailly P, Maurice N and Charpier S. (2007) The pars reticulata of the substantia nigra: a window to basal ganglia output. Prog Brain Res 160:151-72 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Substantia nigra pars reticulata principal cellDistal equivalent dendriteGabaAstriatonigral and pallidonigral input"The reversal potential as well as the complete blockade of the striatal-evoked synaptic events by bicuculline or picrotoxin indicate that neurotransmission between striatonigral fibers and SNr cells is due to activation of GABAA receptors with chloride ions as charge carriers" Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellMiddle equivalent dendriteGabaAstriatonigral and pallidonigral input"The reversal potential as well as the complete blockade of the striatal-evoked synaptic events by bicuculline or picrotoxin indicate that neurotransmission between striatonigral fibers and SNr cells is due to activation of GABAA receptors with chloride ions as charge carriers" Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellProximal equivalent dendriteGabaAstriatonigral and pallidonigral input"The reversal potential as well as the complete blockade of the striatal-evoked synaptic events by bicuculline or picrotoxin indicate that neurotransmission between striatonigral fibers and SNr cells is due to activation of GABAA receptors with chloride ions as charge carriers" Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellDistal equivalent dendriteGabaBstriatonigral and pallidonigral input"The presence of GABAB receptor subtypes BR1 and BR2 on the presynaptic and postsynaptic membranes of GABAergic striatonigral synapses and glutamatergic STN like terminals indicates that besides GABAA, GABAB receptors are also implicated in GABAergic striatonigral transmission." Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellMiddle equivalent dendriteGabaBstriatonigral and pallidonigral input"The presence of GABAB receptor subtypes BR1 and BR2 on the presynaptic and postsynaptic membranes of GABAergic striatonigral synapses and glutamatergic STN like terminals indicates that besides GABAA, GABAB receptors are also implicated in GABAergic striatonigral transmission." Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellProximal equivalent dendriteGabaBstriatonigral and pallidonigral input"The presence of GABAB receptor subtypes BR1 and BR2 on the presynaptic and postsynaptic membranes of GABAergic striatonigral synapses and glutamatergic STN like terminals indicates that besides GABAA, GABAB receptors are also implicated in GABAergic striatonigral transmission." Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellDistal equivalent dendriteNMDA subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellMiddle equivalent dendriteNMDAsubthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellProximal equivalent dendriteNMDAsubthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellProximal equivalent dendriteAMPAsubthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellMiddle equivalent dendriteAMPAsubthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellDistal equivalent dendriteAMPAsubthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellDistal equivalent dendritemGluR1subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellMiddle equivalent dendritemGluR1subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellProximal equivalent dendritemGluR1subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellDistal equivalent dendritemGluR5subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellMiddle equivalent dendritemGluR5subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellProximal equivalent dendritemGluR5subthalamonigral input“In vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity Féger J and Robledo P, 1991584 . The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in Deniau JM et al, 2007583
Substantia nigra pars reticulata principal cellAxon terminalGabaThalamic and cortical connections“From rodents to primates, the SNr and GPi innervate thalamic and brain stem nuclei connected to motor, prefrontal, parietal and temporal associative cortical areas offering an access for BG to control motor, cognitive, as well as emotional–motivational processes.” Deniau JM et al, 2007583

References
583. Deniau JM, Mailly P, Maurice N and Charpier S. (2007) The pars reticulata of the substantia nigra: a window to basal ganglia output. Prog Brain Res 160:151-72 [Journal] .
584. Féger J and Robledo P. (1991) The Effects of Activation or Inhibition of the Subthalamic Nucleus on the Metabolic and Electrophysiological Activities Within the Pallidal Complex and Substantia Nigra in the Rat. Eur J Neurosci 3:947-952.
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