1. Jahr CE and Nicoll RA. (1982) An intracellular analysis of dendrodendritic inhibition in the turtle in vitro olfactory bulb. J Physiol 326:213-34.

NeuronCompartmentPropertyConnectivityNotes
Olfactory bulb main mitral GLU cellSomaGabaA.Synaptic inhibition of mitral cells: Yamamoto et al, 1962; (PHILLIPS CG et al, 1963 [rabbit]2 ). granule cell dendrodendritic synapses: (Rall W et al, 19663 ). (Rall W and Shepherd GM, 19684 ). granule cells are GABAergic: (Ribak CE et al, 19775 ). Fast IPSP, blocked by bicuculline and low Cl- (Nowycky MC et al, 1981 [turtle]6 ). see also (Jahr CE and Nicoll RA, 19821 ). Identification of subunit mRNAs (Laurie DJ et al, 1992 [rat]7 ). The kinetics of GABA currents were studied using flash photolysis of caged GABA (Lowe G, 20028 ).
Olfactory bulb main tufted middle GLU cellSomaGabaA.Synaptic inhibition of mitral cells: Yamamoto et al, 1962; (PHILLIPS CG et al, 1963 [rabbit]2 ). granule cell dendrodendritic synapses: (Rall W et al, 19663 ). (Rall W and Shepherd GM, 19684 ). granule cells are GABAergic: (Ribak CE et al, 19775 ). Fast IPSP, blocked by bicuculline and low Cl- (Nowycky MC et al, 1981 [turtle]6 ). see also (Jahr CE and Nicoll RA, 19821 ). Identification of subunit mRNAs (Laurie DJ et al, 1992 [rat]7 ). The kinetics of GABA currents were studied using flash photolysis of caged GABA (Lowe G, 20028 ).
Olfactory bulb main interneuron granule MC GABA cellDistal equivalent dendriteGabaonto mitral cell to exert self inhibition or lateral inhibitionGAD-positive gemmules (spines) of granule cells were observed to form reciprocal dendrodentritic synaptic junctions with mitral cell dentrites which lacked reaction product.(Ribak CE et al, 19775 ). GABAergic inhibitory synapses onto mitral cells, through dendrodendritic spine synapse: possibly two types: self inhibition and lateral inhibition. (Rall W and Shepherd GM, 19684 ). (Isaacson JS and Strowbridge BW, 19989 ). Mitral-cell soma-dendrites act as a presynaptic terminal to the granule cell; the circuit is recurrent onto the injected cell; and the inhibitory transmitter is GABA (Jahr CE and Nicoll RA, 19821 ). and Shepherd GM ed. Synaptic Organization of the Brain, 1998. p182)GABA release onto mitral: spontaneous and gltamate-evoked. Moreover, activation of muscarinic receptors modulates GABAergic synaptic inputs onto mitral cell.(Castillo PE et al, 199910 ). Selective localization of GABA receptors at symmetric synapses ( and of gluR at asymmetric synapses.) (Sassoè-Pognetto M and Ottersen OP, 200011 ).
Olfactory bulb main interneuron granule TC GABA cellDistal equivalent dendriteGabaonto tuft cell to exert self inhibition or lateral inhibitionGAD-positive gemmules (spines) of granule cells were observed to form reciprocal dendrodentritic synaptic junctions with mitral cell dentrites which lacked reaction product.(Ribak CE et al, 19775 ). GABAergic inhibitory synapses onto mitral cells, through dendrodendritic spine synapse: possibly two types: self inhibition and lateral inhibition. (Rall W and Shepherd GM, 19684 ). (Isaacson JS and Strowbridge BW, 19989 ). Mitral-cell soma-dendrites act as a presynaptic terminal to the granule cell; the circuit is recurrent onto the injected cell; and the inhibitory transmitter is GABA (Jahr CE and Nicoll RA, 19821 ). and Shepherd GM ed. Synaptic Organization of the Brain, 1998. p182) GABA release onto mitral: spontaneous and gltamate-evoked. Moreover, activation of muscarinic receptors modulates GABAergic synaptic inputs onto mitral cell.(Castillo PE et al, 199910 ). Selective localization of GABA receptors at symmetric synapses ( and of gluR at asymmetric synapses.) (Sassoè-Pognetto M and Ottersen OP, 200011 ).
Olfactory bulb main mitral GLU cellAxon hillockI Na,t.Blockade of fast spike by TTX (Mori K et al, 1981 [turtle]12 ). (Jahr CE and Nicoll RA, 19821 ). Estimated: HH model slightly modified from Traub, 1982 (Bhalla US and Bower JM, 1993 [vertebrate]13 ).
Olfactory bulb main tufted middle GLU cellAxon hillockI Na,t.Blockade of fast spike by TTX (Mori K et al, 1981 [turtle]12 ). (Jahr CE and Nicoll RA, 19821 ). Estimated: HH model slightly modified from Traub, 1982 (Bhalla US and Bower JM, 1993 [vertebrate]13 ).

Classical References: first publications on each compartmental property; search PubMed for complete list
1.  Jahr CE and Nicoll RA. (1982) An intracellular analysis of dendrodendritic inhibition in the turtle in vitro olfactory bulb. J Physiol 326:213-34.
2.  PHILLIPS CG, POWELL TP and SHEPHERD GM. (1963) RESPONSES OF MITRAL CELLS TO STIMULATION OF THE LATERAL OLFACTORY TRACT IN THE RABBIT. J Physiol 168:65-88.
3.  Rall W, Shepherd GM, Reese TS and Brightman MW. (1966) Dendrodendritic synaptic pathway for inhibition in the olfactory bulb. Exp Neurol 14:44-56.
4.  Rall W and Shepherd GM. (1968) Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb. J Neurophysiol 31:884-915 [Journal] .
5.  Ribak CE, Vaughn JE, Saito K, Barber R and Roberts E. (1977) Glutamate decarboxylase localization in neurons of the olfactory bulb. Brain Res 126:1-18.
6.  Nowycky MC, Mori K and Shepherd GM. (1981) GABAergic mechanisms of dendrodendritic synapses in isolated turtle olfactory bulb. J Neurophysiol 46:639-48 [Journal] .
7.  Laurie DJ, Wisden W and Seeburg PH. (1992) The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci 12:4151-72.
8.  Lowe G. (2002) Inhibition of backpropagating action potentials in mitral cell secondary dendrites. J Neurophysiol 88:64-85 [Journal] .
9.  Isaacson JS and Strowbridge BW. (1998) Olfactory reciprocal synapses: dendritic signaling in the CNS. Neuron 20:749-61.
10.  Castillo PE, Carleton A, Vincent JD and Lledo PM. (1999) Multiple and opposing roles of cholinergic transmission in the main olfactory bulb. J Neurosci 19:9180-91.
11.  Sassoè-Pognetto M and Ottersen OP. (2000) Organization of ionotropic glutamate receptors at dendrodendritic synapses in the rat olfactory bulb. J Neurosci 20:2192-201.
12.  Mori K, Nowycky MC and Shepherd GM. (1981) Electrophysiological analysis of mitral cells in the isolated turtle olfactory bulb. J Physiol 314:281-94.
13.  Bhalla US and Bower JM. (1993) Exploring parameter space in detailed single neuron models: simulations of the mitral and granule cells of the olfactory bulb. J Neurophysiol 69:1948-65 [Journal] .