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O-LM interneuron model (Lawrence et al. 2006)
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Simulation Platform
Accession:
102288
Exploring the kinetics and distribution of the muscarinic potassium channel, IM, in 2 O-LM interneuron morphologies. Modulation of the ion channel by drugs such as XE991 (antagonist) and retigabine (agonist) are simulated in the models to examine the role of IM in spiking properties.
Reference:
1 .
Lawrence JJ, Saraga F, Churchill JF, Statland JM, Travis KE, Skinner FK, McBain CJ (2006) Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons.
J Neurosci
26
:12325-38
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA1 interneuron oriens alveus GABA cell;
Channel(s):
I L high threshold;
I N;
I T low threshold;
I A;
I K;
I K,leak;
I M;
I h;
I K,Ca;
Gap Junctions:
Receptor(s):
Muscarinic;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Ion Channel Kinetics;
Oscillations;
Detailed Neuronal Models;
Action Potentials;
Implementer(s):
Search NeuronDB
for information about:
Hippocampus CA1 interneuron oriens alveus GABA cell
;
Muscarinic
;
I L high threshold
;
I N
;
I T low threshold
;
I A
;
I K
;
I K,leak
;
I M
;
I h
;
I K,Ca
;
Download the displayed file
/
RichyandStarfish
readme.html
cad.mod
*
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Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
ICaL.mod
*
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Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
ICaT.mod
*
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Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ih.mod
IKa.mod
*
Other models using IKa.mod:
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
IKCa.mod
*
Other models using IKCa.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ikdrf.mod
*
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Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ikdrfaxon.mod
*
Other models using Ikdrfaxon.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ikdrs.mod
*
Other models using Ikdrs.mod:
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ikdrsaxon.mod
*
Other models using Ikdrsaxon.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ikleakaxon.mod
*
Other models using Ikleakaxon.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ikleaksd.mod
*
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
IMminret.mod
*
Other models using IMminret.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
IMmintau.mod
*
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Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ipassaxon.mod
*
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Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Ipasssd.mod
*
Other models using Ipasssd.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Naaxon.mod
*
Other models using Naaxon.mod:
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Nadend.mod
*
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Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
Nasoma.mod
*
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Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
Multi-comp. CA1 O-LM interneuron model with varying dendritic Ih distributions (Sekulic et al 2015)
SIN.mod
*
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fig9.hoc
initactiveproxRichy.hoc
initactiveproxStarfish.hoc
initactivesdRichy.hoc
initactivesdStarfish.hoc
initsomaRichy.hoc
initsomaStarfish.hoc
mosinit.hoc
Richytrunctest2.hoc
screenshot.jpg
Starfishtrunc.hoc
load_file("nrngui.hoc") load_file("fig9.hoc")
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