GPi/GPe neuron models (Johnson and McIntyre 2008)

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Accession:114685
Model files for two types of non-human primate neurons used in the paper: simplified versions of 1) a GPi neuron and 2) a GPe axon collateralizing in GPi en route to STN.
Reference:
1 . Johnson MD, McIntyre CC (2008) Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation. J Neurophysiol 100:2549-63 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Axon;
Brain Region(s)/Organism:
Cell Type(s): Globus pallidus neuron;
Channel(s): I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Axonal Action Potentials; Parkinson's; Extracellular Fields;
Implementer(s): Johnson, Matthew D [johnsom11 at ccf.org];
Search NeuronDB for information about:  I Sodium; I Calcium; I Potassium;
TITLE sodium leak for GPi model neuron

COMMENT 
 
 Sodium leak.  This consists of a TTX-insensitive sodium current, which
 is active between spikes, has some voltage dependence, and underlies the
 resting membrane potential (AthertonBevan2005).  Other cation may be
 involved but for simplicity, only Na+ current was modeled.

ENDCOMMENT

UNITS {
   (mv) = (millivolt)
   (mA) = (milliamp)
}

NEURON {
    SUFFIX NaL
    USEION na READ ena,nai WRITE ina
    RANGE gna,inaL
    GLOBAL gmax_naL
}

PARAMETER {
    v (mV)
    gna = 2.8e-5   (mho/cm2)
    inaL = 0.0      (mA/cm2)
    ena
    nai
    celsius
}

ASSIGNED { 
    ina (mA/cm2)
    gmax_naL
}

BREAKPOINT {
    ina	= gna*gmax_naL*(v-ena)
    inaL = ina
}

INITIAL {
    gmax_naL = 1
}

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