GPi/GPe neuron models (Johnson and McIntyre 2008)

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Accession:114685
Model files for two types of non-human primate neurons used in the paper: simplified versions of 1) a GPi neuron and 2) a GPe axon collateralizing in GPi en route to STN.
Reference:
1 . Johnson MD, McIntyre CC (2008) Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation. J Neurophysiol 100:2549-63 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Axon;
Brain Region(s)/Organism:
Cell Type(s): Globus pallidus neuron;
Channel(s): I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Axonal Action Potentials; Parkinson's; Extracellular Fields;
Implementer(s): Johnson, Matthew D [johnsom11 at ccf.org];
Search NeuronDB for information about:  I Sodium; I Calcium; I Potassium;
TITLE passive membrane properties for GPi

COMMENT

Nakanishi1990 measured the average input resistances of EP neurons
  Type I  --> 126 MOhm (8.9286e-9 mho)
  Type II --> 145 MOhm (6.8966e-9 mho)
All recordings were at 36degC, so there is no need to add a temperature
correction factor.  Note that if simulation involves Cs+ or TEA, it is
necessary to adjust gpas accordingly (See Fig1D).

ENDCOMMENT

UNITS {
    (mV) = (millivolt)
    (mA) = (milliamp)
}

INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}

NEURON {
    SUFFIX GPi
    RANGE gpas, epas
    NONSPECIFIC_CURRENT ipas
}

PARAMETER {
    v (mV)
    dt (ms)
    gpas  = 6.8027e-5 (mho/cm2) <0,1e9>     
    epas  = -60 (mV)                        
    celsius
}

ASSIGNED { 
    ipas (mA/cm2)
}

BREAKPOINT {
    ipas = gpas*(v - epas)
}

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