ModelDB: A Model of Multiple Spike Initiation Zones in the Leech C-interneuron (Crisp 2009)

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A Model of Multiple Spike Initiation Zones in the Leech C-interneuron (Crisp 2009)

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Accession:116575

The leech C-interneuron and its electrical synapse with the S-interneuron exhibit unusual properties: an asymmetric delay when impulses travel from one soma to the other, and graded C-interneuron impulse amplitudes under elevated divalent cation concentrations. These properties have been simulated using a SNNAP model in which the C-interneuron has multiple, independent spike initiation zones associated with individual electrical junctions with the C-interneuron.
Reference:
1 . Crisp KM (2009) Multiple spike initiation zones in a neuron implicated in learning in the leech: a computational model. Invert Neurosci 9:1-10 [PubMed]