This model was used to confirm and support experimental data
suggesting that the neuronal/circuitry changes associated with temporal lobe epilepsy,
including Ih-dependent inductive mechanisms, can disrupt hippocampal theta function.
Marcelin B, Chauvière L, Becker A, Migliore M, Esclapez M, Bernard C (2009) h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy. Neurobiol Dis 33:436-47 [PubMed]