Sodium potassium ATPase pump (Chapman et al. 1983)

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Accession:120692
The electrochemical properties of a widely accepted six-step reaction scheme for the Na,K-ATPase have been studied by computer simulation.
Reference:
1 . Chapman JB, Johnson EA, Kootsey JM (1983) Electrical and biochemical properties of an enzyme model of the sodium pump. J Membr Biol 74:139-53 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Electrogenic pump;
Brain Region(s)/Organism:
Cell Type(s): Hodgkin-Huxley neuron;
Channel(s): Na/K pump;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Sodium pump;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB for information about:  Na/K pump;
{load_file("nrngui.hoc")}
create soma
{diam=10 L=100/PI/diam}
insert nakpump

proc figs() {
	xpanel("figures")
	xbutton("Figure 2-3", "load(\"fig2-3.hoc\")")
	xbutton("Figure 4-6", "load(\"fig4-6.hoc\")")
	xbutton("Figure 7", "load(\"fig7.hoc\")")
	xbutton("Figure 8-10", "load(\"fig8-10.hoc\")")
	xbutton("Figure 11-12", "load(\"fig11-12.hoc\")")
	xpanel(20, 100)
}

proc load() {local i localobj gl
	gl = new List("Graph")
	objref save_window_
	graphList[0].remove_all()
	doNotify()
	if (numarg() == 1) {
		load_file(1, $s1)
	}
}

proc std() {
        totalpump_nakpump = 1.25e-13
        nain_nakpump = 9.6
        naout_nakpump = 140
        kin_nakpump = 150.4
        kout_nakpump = 5.4
        atp_nakpump = 4.99
        p_nakpump = 4.95
        adp_nakpump = 0.06
        T_nakpump = 310

        f1_nakpump = 2.5e11
        b1_nakpump = 1e5
        f2_nakpump = 1e4
        b2_nakpump = 1e5
        f3_nakpump = 172
        b3_nakpump = 1.72e4
        f4_nakpump = 1.5e7
        b4_nakpump = 2e5
        f5_nakpump = 2e6
        b5_nakpump = 30
        f6_nakpump = 1.15e4
        b6_nakpump = 6e8

        beta_nakpump = .5
        a3_nakpump = 0
        a5_nakpump = 1
}

figs()

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