Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Biophysically detailed model of the mouse sino-atrial node cell (Kharche et al. 2011)
Download zip file
Help downloading and running models
This model is developed to study the role of various electrophysiological mechanisms in generating cardiac pacemaking action potentials (APs).The model incorporates membrane ionic currents and intracellular mechanisms contributing to spontaneous mouse SAN APs. The model was validated by testing the functional roles of individual membrane currents in one and multiple parameter analyses.The roles of intracellular Ca2+-handling mechanisms on cardiac pacemaking were also investigated in the model.
Kharche S, Yu J, Lei M, Zhang H (2011) A mathematical model of action potentials of mouse sinoatrial node cells with molecular bases.
Am J Physiol Heart Circ Physiol
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Cardiac atrial cell;
C or C++ program;
Action Potential Initiation;
Kharche, Sanjay ;
for information about:
File not selected
<- Select file from this column.
Loading data, please wait...