Ca1 pyramidal neuron: reduction model (Marasco et al. 2012)

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Accession:146376
"... Here we introduce a new, automatic and fast method to map realistic neurons into equivalent reduced models running up to >40 times faster while maintaining a very high accuracy of the membrane potential dynamics during synaptic inputs, and a direct link with experimental observables. The mapping of arbitrary sets of synaptic inputs, without additional fine tuning, would also allow the convenient and efficient implementation of a new generation of large-scale simulations of brain regions reproducing the biological variability observed in real neurons, with unprecedented advances to understand higher brain functions."
Reference:
1 . Marasco A, Limongiello A, Migliore M (2012) Fast and accurate low-dimensional reduction of biophysically detailed neuron models. Sci Rep 2:928 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA1 pyramidal GLU cell;
Channel(s): I Na,t; I A; I K; I h;
Gap Junctions:
Receptor(s): AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Detailed Neuronal Models;
Implementer(s): Limongiello, Alessandro [alessandro.limongiello at unina.it];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; AMPA; I Na,t; I A; I K; I h;
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reduction1.0
MaxStim_Output
filelog_geoc70863.hoc.txt
NSpike_geoc70863.hoc.xls
                            
Log file:

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 40
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 36


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
40	36.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 60
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 45


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
60	45.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 80
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 50


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
80	50.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 100
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 58


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
100	58.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 120
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 63


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
120	63.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 140
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 66


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
140	66.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 160
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 70


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
160	70.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 180
positionSeed: 2181150
poissonSeed: 1505849
NSpike Morfologico: 79


%%%%%%%%%%%
synNum	muSpikesOr	sdSpikesOr
180	79.00	0.00
%%%%%%%%%%%

--------------------------------------------------
Morphology: geoc70863.hoc
synNum: 200
positionSeed: 2181150
poissonSeed: 1505849

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