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Chirp stimulus responses in a morphologically realistic model (Narayanan and Johnston, 2007)
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Model Information
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Accession:
147578
...we built a multicompartmental model with a morphologically realistic three-dimensional reconstruction of a CA1 pyramidal neuron. The only active conductance we added to the model was the h conductance. ... We conclude that experimentally observed gradient in density of h channels could theoretically account for experimentally observed gradient in resonance properties (Narayanan and Johnston, 2007).
Reference:
1 .
Narayanan R, Johnston D (2007) Long-term potentiation in rat hippocampal neurons is accompanied by spatially widespread changes in intrinsic oscillatory dynamics and excitability.
Neuron
56
:1061-75
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Dendrite;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
I h;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Ion Channel Kinetics;
Active Dendrites;
Detailed Neuronal Models;
Implementer(s):
Narayanan, Rishikesh [rishi at iisc.ac.in];
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
I h
;
Download the displayed file
/
MultiChirp
Output
README.txt
h.mod
*
Other models using h.mod:
Resonance properties through Chirp stimulus responses (Narayanan Johnston 2007, 2008)
ChirpI.txt
*
Other models using ChirpI.txt:
Resonance properties through Chirp stimulus responses (Narayanan Johnston 2007, 2008)
Fig8C.hoc
mosinit.hoc
n123.hoc
*
Other models using n123.hoc:
Active dendrites shape signaling microdomains in hippocampal neurons (Basak & Narayanan 2018)
ObliquePath.hoc
*
Other models using ObliquePath.hoc:
Active dendrites shape signaling microdomains in hippocampal neurons (Basak & Narayanan 2018)
Amyloid-beta effects on release probability and integration at CA3-CA1 synapses (Romani et al. 2013)
CA1 pyramidal neuron (Combe et al 2018)
CA1 pyramidal neuron: as a 2-layer NN and subthreshold synaptic summation (Poirazi et al 2003)
CA1 pyramidal neuron: dendritic Ca2+ inhibition (Muellner et al. 2015)
CA1 pyramidal neuron: depolarization block (Bianchi et al. 2012)
CA1 pyramidal neuron: synaptic plasticity during theta cycles (Saudargiene et al. 2015)
CA1 pyramidal neuron: synaptically-induced bAP predicts synapse location (Sterratt et al. 2012)
Linear vs non-linear integration in CA1 oblique dendrites (Gómez González et al. 2011)
Modelling reduced excitability in aged CA1 neurons as a Ca-dependent process (Markaki et al. 2005)
oblique-paths.hoc
*
Other models using oblique-paths.hoc:
Active dendrites shape signaling microdomains in hippocampal neurons (Basak & Narayanan 2018)
Trunk_RN.txt
Trunk_Z.txt
load_file("nrngui.hoc") load_file("Fig8C.hoc")
Load Model Views
Compute Input Resistances Along Trunk
Save Local Chirp Responses for Locations Along Trunk
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