Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)

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Accession:150284
"… We present a new event-driven algorithm to synchronize different neuronal models, which decreases computational time and avoids superfluous synchronizations. The algorithm is implemented in the TimeScales framework. We demonstrate its use by simulating a new multiscale model of the Medium Spiny Neuron of the Neostriatum. The model comprises over a thousand dendritic spines, where the electrical model interacts with the respective instances of a biochemical model. Our results show that a multiscale model is able to exhibit changes of synaptic plasticity as a result of the interaction between electrical and biochemical signaling. …"
Reference:
1 . Mattioni M, Le Novère N (2013) Integration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatum. PLoS One 8:e66811 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Synapse;
Brain Region(s)/Organism: Striatum;
Cell Type(s): Neostriatum medium spiny direct pathway GABA cell;
Channel(s): I Na,p; I Na,t; I T low threshold; I A; I K,Ca; I CAN; I Calcium; I A, slow; I Krp; I R; I Q;
Gap Junctions:
Receptor(s):
Gene(s): Kv4.2 KCND2; Kv1.2 KCNA2; Cav1.3 CACNA1D; Cav1.2 CACNA1C; Kv2.1 KCNB1;
Transmitter(s):
Simulation Environment: NEURON; Python;
Model Concept(s): Synaptic Plasticity; Signaling pathways; Calcium dynamics; Multiscale;
Implementer(s): Mattioni, Michele [mattioni at ebi.ac.uk];
Search NeuronDB for information about:  Neostriatum medium spiny direct pathway GABA cell; I Na,p; I Na,t; I T low threshold; I A; I K,Ca; I CAN; I Calcium; I A, slow; I Krp; I R; I Q;
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        <p xmlns="http://www.w3.org/1999/xhtml">This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2008 The BioModels Team.
        
        <br/>For more information see the 
        
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        <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&amp;pubmedid=16381960" target="_blank"> Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.</a>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> species_22 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_22 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000022" id="function_12" name="function_4_Transition camT_ca2_AC to camR_ca2_AC">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> species_23 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_23 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_13 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000023" id="function_21" name="function_4_Transition camT_ca3_ABC to camR_ca3_ABC">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> species_28 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_28 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000024" id="function_22" name="function_4_Transition camT_ca3_ABD to camR_ca3_ABD">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_29 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_29 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000025" id="function_23" name="function_4_Transition camT_ca3_ACD to camR_ca3_ACD">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_30 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_30 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000026" id="function_24" name="function_4_Transition camT_ca3_BCD to camR_ca3_BCD">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_31 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_31 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000027" id="function_25" name="function_4_Transition camR_ca4_ABCD to camT_ca4_ABCD">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> parameter_9 </ci>
          </bvar>
          <bvar>
            <ci> species_16 </ci>
          </bvar>
          <apply>
            <times/>
            <ci> species_16 </ci>
            <ci> parameter_9 </ci>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition metaid="metaid_0000028" id="function_26" name="function_4_Transition camT_ca4_ABCD to camR_ca4_ABCD">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_32 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_32 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
  </listOfFunctionDefinitions>
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    <compartment metaid="metaid_0000090" id="compartment_0" name="Spine" size="1e-15">
      <annotation>
        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
          <rdf:Description rdf:about="#metaid_0000090">
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                <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0043197"/>
              </rdf:Bag>
            </bqbiol:is>
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        </rdf:RDF>
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          <rdf:Description rdf:about="#metaid_0000091">
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                <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/>
              </rdf:Bag>
            </bqbiol:isVersionOf>
            <bqbiol:isHomologTo>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:uniprot:P62158"/>
              </rdf:Bag>
            </bqbiol:isHomologTo>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
    </species>
    <species metaid="metaid_0000092" id="species_1" name="ca" compartment="compartment_0" initialConcentration="1e-05">
      <annotation>
        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
          <rdf:Description rdf:about="#metaid_0000092">
            <bqbiol:is>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/>
                <rdf:li rdf:resource="urn:miriam:kegg.compound:C00076"/>
              </rdf:Bag>
            </bqbiol:is>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
    </species>
    <species metaid="metaid_0000093" id="species_2" name="camR_ca1_A" compartment="compartment_0" initialConcentration="0">
      <annotation>
        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
          <rdf:Description rdf:about="#metaid_0000093">
            <bqbiol:hasPart>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/>
                <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/>
              </rdf:Bag>
            </bqbiol:hasPart>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
    </species>
    <species metaid="metaid_0000094" id="species_3" name="camR_ca1_B" compartment="compartment_0" initialConcentration="0">
      <annotation>
        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
          <rdf:Description rdf:about="#metaid_0000094">
            <bqbiol:hasPart>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.chebi:CHEBI%3A29108"/>
                <rdf:li rdf:resource="urn:miriam:kegg.compound:C00391"/>
              </rdf:Bag>
            </bqbiol:hasPart>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
    </species>
    <species metaid="metaid_0000095" id="species_4" name="camR_ca1_C" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000096" id="species_5" name="camR_ca1_D" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000097" id="species_6" name="camR_ca2_AB" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000098" id="species_7" name="camR_ca2_AC" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000099" id="species_8" name="camR_ca2_AD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000100" id="species_9" name="camR_ca2_BC" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000101" id="species_10" name="camR_ca2_BD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000102" id="species_11" name="camR_ca2_CD" compartment="compartment_0" initialConcentration="0"/>
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    <species metaid="metaid_0000104" id="species_13" name="camR_ca3_ABD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000105" id="species_14" name="camR_ca3_ACD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000106" id="species_15" name="camR_ca3_BCD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000107" id="species_16" name="camR_ca4_ABCD" compartment="compartment_0" initialConcentration="0"/>
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    <species metaid="metaid_0000109" id="species_18" name="camT_ca1_A" compartment="compartment_0" initialConcentration="0"/>
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    <species metaid="metaid_0000111" id="species_20" name="camT_ca1_C" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000112" id="species_21" name="camT_ca1_D" compartment="compartment_0" initialConcentration="0"/>
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    <species metaid="metaid_0000121" id="species_30" name="camT_ca3_ACD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000122" id="species_31" name="camT_ca3_BCD" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000123" id="species_32" name="camT_ca4_ABCD" compartment="compartment_0" initialConcentration="0"/>
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        <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
          <rdf:Description rdf:about="#metaid_0000124">
            <bqbiol:isVersionOf>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:interpro:IPR015742"/>
              </rdf:Bag>
            </bqbiol:isVersionOf>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
    </species>
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        </rdf:RDF>
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    <species metaid="metaid_0000153" id="species_62" name="camR_ca3_ABC_PP2B" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000154" id="species_63" name="camR_ca3_ABD_PP2B" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000155" id="species_64" name="camR_ca3_ACD_PP2B" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000156" id="species_65" name="camR_ca3_BCD_PP2B" compartment="compartment_0" initialConcentration="0"/>
    <species metaid="metaid_0000157" id="species_66" name="camR_ca4_ABCD_PP2B" compartment="compartment_0" initialConcentration="0"/>
  </listOfSpecies>
  <listOfParameters>
    <parameter metaid="metaid_0000029" id="parameter_0" name="kon" value="1000000"/>
    <parameter metaid="metaid_0000030" id="parameter_1" name="koffRA" value="8.32" constant="false"/>
    <parameter metaid="metaid_0000031" id="parameter_2" name="koffRB" value="0.0166" constant="false"/>
    <parameter metaid="metaid_0000032" id="parameter_3" name="koffRC" value="17.4" constant="false"/>
    <parameter metaid="metaid_0000033" id="parameter_4" name="koffRD" value="0.0145" constant="false"/>
    <parameter metaid="metaid_0000034" id="parameter_5" name="koffTA" value="2101.0101010101" constant="false"/>
    <parameter metaid="metaid_0000035" id="parameter_6" name="koffTB" value="4.19191919191919" constant="false"/>
    <parameter metaid="metaid_0000036" id="parameter_7" name="koffTC" value="4393.93939393939" constant="false"/>
    <parameter metaid="metaid_0000037" id="parameter_8" name="koffTD" value="3.66161616161616" constant="false"/>
    <parameter metaid="metaid_0000038" id="parameter_9" name="kRT" value="1000000"/>
    <parameter metaid="metaid_0000039" id="parameter_10" name="kTR" value="48.3792936623125" constant="false"/>
    <parameter metaid="metaid_0000040" id="parameter_11" name="cA" value="0.00396"/>
    <parameter metaid="metaid_0000041" id="parameter_12" name="cB" value="0.00396"/>
    <parameter metaid="metaid_0000042" id="parameter_13" name="cC" value="0.00396"/>
    <parameter metaid="metaid_0000043" id="parameter_14" name="cD" value="0.00396"/>
    <parameter metaid="metaid_0000044" id="parameter_15" name="konCaMKII" value="3200000"/>
    <parameter metaid="metaid_0000045" id="parameter_16" name="koffCaMKII" value="0.343"/>
    <parameter metaid="metaid_0000046" id="parameter_17" name="konPP2B" value="46000000"/>
    <parameter metaid="metaid_0000047" id="parameter_18" name="koffPP2B" value="0.0013"/>
    <parameter metaid="metaid_0000048" id="parameter_19" name="free_camR_ca3_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000049" id="parameter_20" name="free_camT_ca3_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000050" id="parameter_21" name="free_cam_ca3_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000051" id="parameter_22" name="cam_ca4_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000052" id="parameter_23" name="CaMKII_camR_ca1" value="0" constant="false"/>
    <parameter metaid="metaid_0000053" id="parameter_24" name="CaMKII_camR_ca2" value="0" constant="false"/>
    <parameter metaid="metaid_0000054" id="parameter_25" name="CaMKII_camR_ca3" value="0" constant="false"/>
    <parameter metaid="metaid_0000055" id="parameter_26" name="total_CaMKII_bound" value="0" constant="false"/>
    <parameter metaid="metaid_0000056" id="parameter_27" name="total CaMKII" value="7e-05" constant="false"/>
    <parameter metaid="metaid_0000057" id="parameter_28" name="CaMKIIbar" value="0" constant="false"/>
    <parameter metaid="metaid_0000058" id="parameter_29" name="PP2B_camR_ca1" value="0" constant="false"/>
    <parameter metaid="metaid_0000059" id="parameter_30" name="PP2B_camR_ca2" value="0" constant="false"/>
    <parameter metaid="metaid_0000060" id="parameter_31" name="PP2B_camR_ca3" value="0" constant="false"/>
    <parameter metaid="metaid_0000061" id="parameter_32" name="total_PP2B_bound" value="0" constant="false"/>
    <parameter metaid="metaid_0000062" id="parameter_33" name="total PP2B" value="1.6e-06" constant="false"/>
    <parameter metaid="metaid_0000063" id="parameter_34" name="PP2Bbar" value="0" constant="false"/>
    <parameter metaid="metaid_0000064" id="parameter_35" name="camR_unbound" value="9.7e-12" constant="false"/>
    <parameter metaid="metaid_0000065" id="parameter_36" name="total camR" value="9.7e-12" constant="false"/>
    <parameter metaid="metaid_0000066" id="parameter_37" name="total camT" value="2e-07" constant="false"/>
    <parameter metaid="metaid_0000067" id="parameter_38" name="Rbar" value="4.84976478640786e-05" constant="false"/>
    <parameter metaid="metaid_0000068" id="parameter_39" name="cam_ca3_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000069" id="parameter_40" name="free_camR_ca2_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000070" id="parameter_41" name="free_camT_ca2_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000071" id="parameter_42" name="free_cam_ca2_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000072" id="parameter_43" name="cam_ca2_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000073" id="parameter_44" name="free_cam_ca1_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000074" id="parameter_45" name="cam_ca1_total" value="0" constant="false"/>
    <parameter metaid="metaid_0000075" id="parameter_46" name="cam_ca0_total" value="2.000097e-07" constant="false"/>
    <parameter metaid="metaid_0000076" id="parameter_47" name="cam_total" value="2.000097e-07" constant="false"/>
    <parameter metaid="metaid_0000077" id="parameter_48" name="moles_bound_ca_per_moles_cam" value="0" constant="false"/>
    <parameter metaid="metaid_0000078" id="parameter_49" name="L" value="20670"/>
    <parameter metaid="metaid_0000079" id="parameter_50" name="KRA" value="8.32e-06"/>
    <parameter metaid="metaid_0000080" id="parameter_51" name="KRB" value="1.66e-08"/>
    <parameter metaid="metaid_0000081" id="parameter_52" name="KRC" value="1.74e-05"/>
    <parameter metaid="metaid_0000082" id="parameter_53" name="KRD" value="1.45e-08"/>
    <parameter metaid="metaid_0000083" id="parameter_54" name="alpha" constant="false"/>
    <parameter metaid="metaid_0000084" id="parameter_55" name="beta" constant="false"/>
    <parameter metaid="metaid_0000085" id="parameter_56" name="gamma" constant="false"/>
    <parameter metaid="metaid_0000086" id="parameter_57" name="delta" constant="false"/>
    <parameter metaid="metaid_0000087" id="parameter_58" name="epsilon" value="4.84976478640786e-05" constant="false"/>
    <parameter metaid="metaid_0000088" id="parameter_59" name="ybar" value="0" constant="false"/>
    <parameter metaid="metaid_0000089" id="parameter_60" name="ybar/(1-ybar)" value="0" constant="false"/>
  </listOfParameters>
  <listOfRules>
    <assignmentRule metaid="metaid_0000158" variable="parameter_1">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_50 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000159" variable="parameter_20">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_28 </ci>
          <ci> species_29 </ci>
          <ci> species_30 </ci>
          <ci> species_31 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000160" variable="parameter_2">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_51 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000161" variable="parameter_3">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_52 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000162" variable="parameter_4">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_53 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000163" variable="parameter_5">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_1 </ci>
          <ci> parameter_11 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000164" variable="parameter_6">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_2 </ci>
          <ci> parameter_12 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000165" variable="parameter_7">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_3 </ci>
          <ci> parameter_13 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000166" variable="parameter_8">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_4 </ci>
          <ci> parameter_14 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000167" variable="parameter_10">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_9 </ci>
          <ci> parameter_49 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000168" variable="parameter_19">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_12 </ci>
          <ci> species_13 </ci>
          <ci> species_14 </ci>
          <ci> species_15 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000169" variable="parameter_21">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_19 </ci>
          <ci> parameter_20 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000170" variable="parameter_22">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_16 </ci>
          <ci> species_32 </ci>
          <ci> species_49 </ci>
          <ci> species_66 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000171" variable="parameter_23">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_35 </ci>
          <ci> species_36 </ci>
          <ci> species_37 </ci>
          <ci> species_38 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000172" variable="parameter_25">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_45 </ci>
          <ci> species_46 </ci>
          <ci> species_47 </ci>
          <ci> species_48 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000173" variable="parameter_24">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_39 </ci>
          <ci> species_40 </ci>
          <ci> species_41 </ci>
          <ci> species_42 </ci>
          <ci> species_43 </ci>
          <ci> species_44 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000174" variable="parameter_26">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_34 </ci>
          <ci> parameter_23 </ci>
          <ci> parameter_24 </ci>
          <ci> parameter_25 </ci>
          <ci> species_49 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000175" variable="parameter_27">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_26 </ci>
          <ci> species_33 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000176" variable="parameter_28">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_26 </ci>
          <ci> parameter_27 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000177" variable="parameter_29">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_52 </ci>
          <ci> species_53 </ci>
          <ci> species_54 </ci>
          <ci> species_55 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000178" variable="parameter_30">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_56 </ci>
          <ci> species_57 </ci>
          <ci> species_58 </ci>
          <ci> species_59 </ci>
          <ci> species_60 </ci>
          <ci> species_61 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000179" variable="parameter_31">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_62 </ci>
          <ci> species_63 </ci>
          <ci> species_64 </ci>
          <ci> species_65 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000180" variable="parameter_32">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_51 </ci>
          <ci> parameter_29 </ci>
          <ci> parameter_30 </ci>
          <ci> parameter_31 </ci>
          <ci> species_66 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000181" variable="parameter_35">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_0 </ci>
          <ci> species_2 </ci>
          <ci> species_3 </ci>
          <ci> species_4 </ci>
          <ci> species_5 </ci>
          <ci> species_6 </ci>
          <ci> species_7 </ci>
          <ci> species_8 </ci>
          <ci> species_9 </ci>
          <ci> species_10 </ci>
          <ci> species_11 </ci>
          <ci> species_12 </ci>
          <ci> species_13 </ci>
          <ci> species_14 </ci>
          <ci> species_15 </ci>
          <ci> species_16 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000182" variable="parameter_33">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_32 </ci>
          <ci> species_50 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000183" variable="parameter_34">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_32 </ci>
          <ci> parameter_33 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000184" variable="parameter_37">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_17 </ci>
          <ci> species_18 </ci>
          <ci> species_19 </ci>
          <ci> species_20 </ci>
          <ci> species_21 </ci>
          <ci> species_22 </ci>
          <ci> species_23 </ci>
          <ci> species_24 </ci>
          <ci> species_25 </ci>
          <ci> species_26 </ci>
          <ci> species_27 </ci>
          <ci> species_28 </ci>
          <ci> species_29 </ci>
          <ci> species_30 </ci>
          <ci> species_31 </ci>
          <ci> species_32 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000185" variable="parameter_36">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_35 </ci>
          <ci> parameter_26 </ci>
          <ci> parameter_32 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000186" variable="parameter_39">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_25 </ci>
          <ci> parameter_31 </ci>
          <ci> parameter_21 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000187" variable="parameter_38">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_36 </ci>
          <apply>
            <plus/>
            <ci> parameter_36 </ci>
            <ci> parameter_37 </ci>
          </apply>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000188" variable="parameter_40">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_6 </ci>
          <ci> species_7 </ci>
          <ci> species_8 </ci>
          <ci> species_9 </ci>
          <ci> species_10 </ci>
          <ci> species_11 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000189" variable="parameter_41">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_22 </ci>
          <ci> species_23 </ci>
          <ci> species_24 </ci>
          <ci> species_25 </ci>
          <ci> species_26 </ci>
          <ci> species_27 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000190" variable="parameter_42">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_40 </ci>
          <ci> parameter_41 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000191" variable="parameter_43">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_42 </ci>
          <ci> parameter_24 </ci>
          <ci> parameter_30 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000192" variable="parameter_44">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_2 </ci>
          <ci> species_3 </ci>
          <ci> species_4 </ci>
          <ci> species_5 </ci>
          <ci> species_18 </ci>
          <ci> species_19 </ci>
          <ci> species_20 </ci>
          <ci> species_21 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000193" variable="parameter_45">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_44 </ci>
          <ci> parameter_23 </ci>
          <ci> parameter_29 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000194" variable="parameter_46">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_0 </ci>
          <ci> species_17 </ci>
          <ci> species_34 </ci>
          <ci> species_51 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000195" variable="parameter_47">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_46 </ci>
          <ci> parameter_45 </ci>
          <ci> parameter_43 </ci>
          <ci> parameter_39 </ci>
          <ci> parameter_22 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000196" variable="parameter_48">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <apply>
            <plus/>
            <apply>
              <times/>
              <cn> 4 </cn>
              <ci> parameter_22 </ci>
            </apply>
            <apply>
              <times/>
              <cn> 3 </cn>
              <ci> parameter_39 </ci>
            </apply>
            <apply>
              <times/>
              <cn> 2 </cn>
              <ci> parameter_43 </ci>
            </apply>
            <ci> parameter_45 </ci>
          </apply>
          <ci> parameter_47 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000197" variable="parameter_54">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> species_16 </ci>
          <apply>
            <plus/>
            <ci> species_16 </ci>
            <ci> species_32 </ci>
          </apply>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000198" variable="parameter_55">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_19 </ci>
          <ci> parameter_21 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000199" variable="parameter_56">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_40 </ci>
          <ci> parameter_42 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000200" variable="parameter_57">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <apply>
            <plus/>
            <ci> species_2 </ci>
            <ci> species_3 </ci>
            <ci> species_4 </ci>
            <ci> species_5 </ci>
          </apply>
          <apply>
            <plus/>
            <ci> species_2 </ci>
            <ci> species_3 </ci>
            <ci> species_4 </ci>
            <ci> species_5 </ci>
            <ci> species_18 </ci>
            <ci> species_19 </ci>
            <ci> species_20 </ci>
            <ci> species_21 </ci>
          </apply>
        </apply>
      </math>
    </assignmentRule>
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    <reaction metaid="metaid_0000233" id="reaction_29" name="Ca dissociating from camR_ca2_AD site A" reversible="false" sboTerm="SBO:0000180">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000234" id="reaction_30" name="Ca dissociating from camR_ca2_BD site B" reversible="false" sboTerm="SBO:0000180">
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            <times/>
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    <reaction metaid="metaid_0000235" id="reaction_31" name="Ca dissociating from camR_ca2_CD site C" reversible="false" sboTerm="SBO:0000180">
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            <times/>
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    <reaction metaid="metaid_0000236" id="reaction_32" name="Ca binding to camR_ca2_AB site C" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000237" id="reaction_33" name="Ca binding to camR_ca2_AB site D" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000238" id="reaction_34" name="Ca binding to camR_ca2_AC site B" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000239" id="reaction_35" name="Ca binding to camR_ca2_AC site D" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000240" id="reaction_36" name="Ca binding to camR_ca2_AD site B" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000241" id="reaction_37" name="Ca binding to camR_ca2_AD site C" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000242" id="reaction_38" name="Ca binding to camR_ca2_BC site A" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000243" id="reaction_39" name="Ca binding to camR_ca2_BC site D" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000244" id="reaction_40" name="Ca binding to camR_ca2_BD site A" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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    <reaction metaid="metaid_0000268" id="reaction_64" name="Ca binding to camT site A " reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_17"/>
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000269" id="reaction_65" name="Ca binding to camT site B" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000270" id="reaction_66" name="Ca binding to camT site C" reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_17"/>
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    </reaction>
    <reaction metaid="metaid_0000271" id="reaction_67" name="Ca binding to camT site D" reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_17"/>
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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        </math>
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    <reaction metaid="metaid_0000272" id="reaction_68" name="Ca dissociating from camT_ca1_A site A" reversible="false" sboTerm="SBO:0000180">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000273" id="reaction_69" name="Ca dissociating from camT_ca1_B site B" reversible="false" sboTerm="SBO:0000180">
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            <times/>
            <ci> compartment_0 </ci>
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    <reaction metaid="metaid_0000274" id="reaction_70" name="Ca dissociating from camT_ca1_C site C" reversible="false" sboTerm="SBO:0000180">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000275" id="reaction_71" name="Ca dissociating from camT_ca1_D site D" reversible="false" sboTerm="SBO:0000180">
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            <times/>
            <ci> compartment_0 </ci>
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        </math>
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    </reaction>
    <reaction metaid="metaid_0000276" id="reaction_72" name="Ca binding to camT_ca1_A site B" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000277" id="reaction_73" name="Ca binding to camT_ca1_A site C" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
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    <reaction metaid="metaid_0000278" id="reaction_74" name="Ca binding to camT_ca1_A site D" reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_18"/>
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
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    <reaction metaid="metaid_0000279" id="reaction_75" name="Ca binding to camT_ca1_B site A" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000280" id="reaction_76" name="Ca binding to camT_ca1_B site C" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
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    <reaction metaid="metaid_0000281" id="reaction_77" name="Ca binding to camT_ca1_B site D" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000282" id="reaction_78" name="Ca binding to camT_ca1_C site A" reversible="false" sboTerm="SBO:0000177">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000283" id="reaction_79" name="Ca binding to camT_ca1_C site B" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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    <reaction metaid="metaid_0000284" id="reaction_80" name="Ca binding to camT_ca1_C site D" reversible="false" sboTerm="SBO:0000177">
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            <times/>
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        </math>
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    <reaction metaid="metaid_0000285" id="reaction_81" name="Ca binding to camT_ca1_D site A" reversible="false" sboTerm="SBO:0000177">
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          <apply>
            <times/>
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    <reaction metaid="metaid_0000286" id="reaction_82" name="Ca binding to camT_ca1_D site B" reversible="false" sboTerm="SBO:0000177">
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          <apply>
            <times/>
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          <apply>
            <times/>
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            <times/>
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            <times/>
            <ci> compartment_0 </ci>
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
            <ci> compartment_0 </ci>
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    <reaction metaid="metaid_0000291" id="reaction_87" name="Ca dissociating from camT_ca2_AC site C" reversible="false" sboTerm="SBO:0000180">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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    </reaction>
    <reaction metaid="metaid_0000292" id="reaction_88" name="Ca dissociating from camT_ca2_AD site A" reversible="false" sboTerm="SBO:0000180">
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        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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        </math>
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            <times/>
            <ci> compartment_0 </ci>
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    <reaction metaid="metaid_0000294" id="reaction_90" name="Ca dissociating from camT_ca2_BC site B" reversible="false" sboTerm="SBO:0000180">
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          <apply>
            <times/>
            <ci> compartment_0 </ci>
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    <reaction metaid="metaid_0000295" id="reaction_91" name="Ca dissociating from camT_ca2_BC site C" reversible="false" sboTerm="SBO:0000180">
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            <times/>
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    <reaction metaid="metaid_0000296" id="reaction_92" name="Ca dissociating from camT_ca2_BD site B" reversible="false" sboTerm="SBO:0000180">
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      <kineticLaw>
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            <times/>
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            <times/>
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      <kineticLaw>
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            <times/>
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      <kineticLaw>
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            <times/>
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    <reaction metaid="metaid_0000300" id="reaction_96" name="Ca binding to camT_ca2_AB site C" reversible="false" sboTerm="SBO:0000177">
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
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            <times/>
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    <reaction metaid="metaid_0000302" id="reaction_98" name="Ca binding to camT_ca2_AC site B" reversible="false" sboTerm="SBO:0000177">
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
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            <ci> parameter_0 </ci>
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      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000303" id="reaction_99" name="Ca binding to camT_ca2_AC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_23 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000304" id="reaction_100" name="Ca binding to camT_ca2_AD site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_24 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000305" id="reaction_101" name="Ca binding to camT_ca2_AD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_24 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000306" id="reaction_102" name="Ca binding to camT_ca2_BC site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_25 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000307" id="reaction_103" name="Ca binding to camT_ca2_BC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_25 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000308" id="reaction_104" name="Ca binding to camT_ca2_BD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_26 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000309" id="reaction_105" name="Ca binding to camT_ca2_BD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_26 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000310" id="reaction_106" name="Ca binding to camT_ca2_CD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_27 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000311" id="reaction_107" name="Ca binding to camT_ca2_CD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_27 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000312" id="reaction_108" name="Ca dissociating from camT_ca3_ABC site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_28 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000313" id="reaction_109" name="Ca dissociating from camT_ca3_ABC site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_28 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000314" id="reaction_110" name="Ca dissociating from camT_ca3_ABD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_29 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000315" id="reaction_111" name="Ca dissociating from camT_ca3_ABD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_29 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000316" id="reaction_112" name="Ca dissociating from camT_ca3_ABD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_29 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000317" id="reaction_113" name="Ca dissociating from camT_ca3_ACD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_30 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000318" id="reaction_114" name="Ca dissociating from camT_ca3_ACD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_30 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000319" id="reaction_115" name="Ca dissociating from camT_ca3_ACD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_30 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000320" id="reaction_116" name="Ca dissociating from camT_ca3_BCD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_31 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000321" id="reaction_117" name="Ca dissociating from camT_ca3_BCD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_31 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000322" id="reaction_118" name="Ca dissociating from camT_ca3_BCD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_31 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000323" id="reaction_119" name="Ca binding to camT_ca3_ABC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_28"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_28 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000324" id="reaction_120" name="Ca binding to camT_ca3_ABD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_29"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_29 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000325" id="reaction_121" name="Ca binding to camT_ca3_ACD site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_30"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_30 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000326" id="reaction_122" name="Ca binding to camT_ca3_BCD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_31"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_31 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000327" id="reaction_123" name="Ca dissociating from camT_ca4_ABCD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000328" id="reaction_124" name="Ca dissociating from camT_ca4_ABCD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000329" id="reaction_125" name="Ca dissociating from camT_ca4_ABCD site B " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000330" id="reaction_126" name="Ca dissociating from camT_ca4_ABCD site A " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000331" id="reaction_127" name="Transition camR to camT" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_0"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_17"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_0 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000332" id="reaction_128" name="Transition camT to camR" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_17"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_10 </ci>
            <ci> species_17 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000333" id="reaction_129" name="Transition camR_ca1_A to camT_ca1_A" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_2"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_18"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_2 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000334" id="reaction_130" name="Transition camR_ca1_B to camT_ca1_B" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_3"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_19"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_3 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000335" id="reaction_131" name="Transition camR_ca1_C to camT_ca1_C" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_4"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_20"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_4 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000336" id="reaction_132" name="Transition camR_ca1_D to camT_ca1_D" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_5"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_21"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_5 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000337" id="reaction_133" name="Transition camT_ca1_A to camR_ca1_A" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_18"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_1 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> species_18 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000338" id="reaction_134" name="Transition camT_ca1_B to camR_ca1_B" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_19"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_2 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> species_19 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000339" id="reaction_135" name="Transition camT_ca1_C to camR_ca1_C" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_20"/>
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      <listOfProducts>
        <speciesReference species="species_4"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_3 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_13 </ci>
              <ci> species_20 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000340" id="reaction_136" name="Transition camT_ca1_D to camR_ca1_D" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_21"/>
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      <listOfProducts>
        <speciesReference species="species_5"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_4 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_14 </ci>
              <ci> species_21 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000341" id="reaction_137" name="Transition camR_ca2_AB to camT_ca2_AB" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_6"/>
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      <listOfProducts>
        <speciesReference species="species_22"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_5 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_9 </ci>
              <ci> species_6 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000342" id="reaction_138" name="Transition camR_ca2_AC to camT_ca2_AC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_7"/>
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      <listOfProducts>
        <speciesReference species="species_23"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_6 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_9 </ci>
              <ci> species_7 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000343" id="reaction_139" name="Transition camR_ca2_AD to camT_ca2_AD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_8"/>
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      <listOfProducts>
        <speciesReference species="species_24"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_7 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_8 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000344" id="reaction_140" name="Transition camR_ca2_BC to camT_ca2_BC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_9"/>
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      <listOfProducts>
        <speciesReference species="species_25"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_8 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_9 </ci>
              <ci> species_9 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000345" id="reaction_141" name="Transition camR_ca2_BD to camT_ca2_BD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_10"/>
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      <listOfProducts>
        <speciesReference species="species_26"/>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_9 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_10 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000346" id="reaction_142" name="Transition camR_ca2_CD to camT_ca2_CD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_11"/>
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      <listOfProducts>
        <speciesReference species="species_27"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_10 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_11 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000347" id="reaction_143" name="Transition camT_ca2_AB to camR_ca2_AB" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_22"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_11 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> species_22 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000348" id="reaction_144" name="Transition camT_ca2_AC to camR_ca2_AC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_23"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_12 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> species_23 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000349" id="reaction_145" name="Transition camT_ca2_AD to camR_ca2_AD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_24"/>
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      <listOfProducts>
        <speciesReference species="species_8"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_13 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_14 </ci>
              <ci> species_24 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000350" id="reaction_146" name="Transition camT_ca2_BC to camR_ca2_BC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_25"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_14 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> species_25 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000351" id="reaction_147" name="Transition camT_ca2_BD to camR_ca2_BD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_26"/>
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      <listOfProducts>
        <speciesReference species="species_10"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_15 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> species_26 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000352" id="reaction_148" name="Transition camT_ca2_CD to camR_ca2_CD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_27"/>
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      <listOfProducts>
        <speciesReference species="species_11"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_16 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_27 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000353" id="reaction_149" name="Transition camR_ca3_ABC to camT_ca3_ABC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_12"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_17 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_9 </ci>
              <ci> species_12 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000354" id="reaction_150" name="Transition camR_ca3_ABD to camT_ca3_ABD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_13"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_18 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_13 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000355" id="reaction_151" name="Transition camR_ca3_ACD to camT_ca3_ACD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_14"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_19 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_14 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000356" id="reaction_152" name="Transition camR_ca3_BCD to camT_ca3_BCD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_15"/>
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      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_20 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_15 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000357" id="reaction_153" name="Transition camT_ca3_ABC to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_21 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> species_28 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000358" id="reaction_154" name="Transition camT_ca3_ABD to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_22 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> species_29 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000359" id="reaction_155" name="Transition camT_ca3_ACD to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_23 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_30 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000360" id="reaction_156" name="Transition camT_ca3_BCD to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_31"/>
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      <listOfProducts>
        <speciesReference species="species_15"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_24 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_31 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000361" id="reaction_157" name="Transition camR_ca4_ABCD to camT_ca4_ABCD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_16"/>
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      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_25 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_16 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000362" id="reaction_158" name="Transition camT_ca4_ABCD to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_32"/>
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      <listOfProducts>
        <speciesReference species="species_16"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_26 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_32 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000363" id="reaction_159" name="CaMKII binding to camR" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_0"/>
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      <listOfProducts>
        <speciesReference species="species_34"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_0 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000364" id="reaction_160" name="CaMKII binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_2"/>
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      <listOfProducts>
        <speciesReference species="species_35"/>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_2 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
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    <reaction metaid="metaid_0000365" id="reaction_161" name="CaMKII binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_3"/>
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      <listOfProducts>
        <speciesReference species="species_36"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_3 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000366" id="reaction_162" name="CaMKII binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_4"/>
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      <listOfProducts>
        <speciesReference species="species_37"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_4 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000367" id="reaction_163" name="CaMKII binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_5"/>
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      <listOfProducts>
        <speciesReference species="species_38"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_5 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
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    <reaction metaid="metaid_0000368" id="reaction_164" name="CaMKII binding to camR_ca2_AB" reversible="false" sboTerm="SBO:0000177">
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        <speciesReference species="species_6"/>
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      <listOfProducts>
        <speciesReference species="species_39"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_6 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000369" id="reaction_165" name="CaMKII binding to camR_ca2_AC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_7"/>
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      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_40"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_7 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000370" id="reaction_166" name="CaMKII binding to camR_ca2_AD" reversible="false">
      <listOfReactants>
        <speciesReference species="species_8"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_8 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000371" id="reaction_167" name="CaMKII binding to camR_ca2_BC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_9"/>
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      </listOfReactants>
      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_9 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000372" id="reaction_168" name="CaMKII binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_10"/>
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      </listOfReactants>
      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_10 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000373" id="reaction_169" name="CaMKII binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_11"/>
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      </listOfReactants>
      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_11 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000374" id="reaction_170" name="CaMKII binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_12"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_12 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000375" id="reaction_171" name="CaMKII binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_13"/>
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      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_13 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000376" id="reaction_172" name="CaMKII binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_14"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_14 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000377" id="reaction_173" name="CaMKII binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_15"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_15 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000378" id="reaction_174" name="CaMKII binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_16"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_16 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000379" id="reaction_175" name="CaMKII dissociation from camR" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_34"/>
      </listOfReactants>
      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_34 </ci>
          </apply>
        </math>
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    </reaction>
    <reaction metaid="metaid_0000380" id="reaction_176" name="CaMKII dissociation from camR_ca1_A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_35"/>
      </listOfReactants>
      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_35 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000381" id="reaction_177" name="CaMKII dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_36"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_36 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000382" id="reaction_178" name="CaMKII dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_37"/>
      </listOfReactants>
      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_37 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000383" id="reaction_179" name="CaMKII dissociation from camR_ca1_D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_38"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_38 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000384" id="reaction_180" name="CaMKII dissociation from camR_ca2_AB" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_39"/>
      </listOfReactants>
      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_39 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000385" id="reaction_181" name="CaMKII dissociation from camR_ca2_AC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_40"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_40 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000386" id="reaction_182" name="CaMKII dissociation from camR_ca2_AD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_41"/>
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      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_41 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000387" id="reaction_183" name="CaMKII dissociation from camR_ca2_BC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_42"/>
      </listOfReactants>
      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_42 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000388" id="reaction_184" name="CaMKII dissociation from camR_ca2_BD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_43"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_43 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000389" id="reaction_185" name="CaMKII dissociation from camR_ca2_CD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_44"/>
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      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_44 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000390" id="reaction_186" name="CaMKII dissociation from camR_ca3_ABC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_45"/>
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      <listOfProducts>
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      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_45 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000391" id="reaction_187" name="CaMKII dissociation from camR_ca3_ABD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_46"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_46 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000392" id="reaction_188" name="CaMKII dissociation from camR_ca3_ACD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_47"/>
      </listOfReactants>
      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_47 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000393" id="reaction_189" name="CaMKII dissociation from camR_ca3_BCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_48"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_48 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000394" id="reaction_190" name="CaMKII dissociation from camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_49"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_49 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000395" id="reaction_191" name="PP2B binding to camR" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_0"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_0 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000396" id="reaction_192" name="PP2B binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000397" id="reaction_193" name="PP2B binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_50 </ci>
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        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000398" id="reaction_194" name="PP2B binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177">
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_50 </ci>
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        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000399" id="reaction_195" name="PP2B binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177">
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000400" id="reaction_196" name="PP2B binding to camR_ca2_AB" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000401" id="reaction_197" name="PP2B binding to camR_ca2_AC" reversible="false" sboTerm="SBO:0000177">
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
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            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000402" id="reaction_198" name="PP2B binding to camR_ca2_AD" reversible="false" sboTerm="SBO:0000177">
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
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            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000403" id="reaction_199" name="PP2B binding to camR_ca2_BC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_9"/>
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      <listOfProducts>
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      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_9 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000404" id="reaction_200" name="PP2B binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_10"/>
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      <listOfProducts>
        <speciesReference species="species_60"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_10 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000405" id="reaction_201" name="PP2B binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_11"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_61"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_11 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000406" id="reaction_202" name="PP2B binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_12"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_62"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_12 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000407" id="reaction_203" name="PP2B binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_13"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_63"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_13 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000408" id="reaction_204" name="PP2B binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_14"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_64"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_14 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000409" id="reaction_205" name="PP2B binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_15"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_65"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_15 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000410" id="reaction_206" name="PP2B binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_16"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_16 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000411" id="reaction_207" name="PP2B dissociation from camR" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_51"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_51 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000412" id="reaction_208" name="PP2B dissociation from camR_ca1_A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_52"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_52 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000413" id="reaction_209" name="PP2B dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_53"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_53 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000414" id="reaction_210" name="PP2B dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_54"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_54 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000415" id="reaction_211" name="PP2B dissociation from camR_ca1_D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_55"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_55 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000416" id="reaction_212" name="PP2B dissociation from camR_ca2_AB" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_56"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_56 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000417" id="reaction_213" name="PP2B dissociation from camR_ca2_AC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_57"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_57 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000418" id="reaction_214" name="PP2B dissociation from camR_ca2_AD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_58"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_58 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000419" id="reaction_215" name="PP2B dissociation from camR_ca2_BC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_59"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_59 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000420" id="reaction_216" name="PP2B dissociation from camR_ca2_BD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_60"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_60 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000421" id="reaction_217" name="PP2B dissociation from camR_ca2_CD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_61"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_61 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000422" id="reaction_218" name="PP2B dissociation from camR_ca3_ABC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_62"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_62 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000423" id="reaction_219" name="PP2B dissociation from camR_ca3_ABD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_63"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_63 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000424" id="reaction_220" name="PP2B dissociation from camR_ca3_ACD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_64"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_64 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000425" id="reaction_221" name="PP2B dissociation from camR_ca3_BCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_65"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_65 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000426" id="reaction_222" name="PP2B dissociation from camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000427" id="reaction_223" name="Ca binding to camR_CaMKII site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_35"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000428" id="reaction_224" name="Ca binding to camR_CaMKII site B " reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_36"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000429" id="reaction_225" name="Ca binding to camR_CaMKII site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_37"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000430" id="reaction_226" name="Ca binding to camR_CaMKII site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_38"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000431" id="reaction_227" name="Ca dissociation from camR_ca1_CaMKII site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_35"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_35 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000432" id="reaction_228" name="Ca dissociation from camR_ca1_CaMKII site C " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_37"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_37 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000433" id="reaction_229" name="Ca dissociation from camR_ca1_CaMKII site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_38"/>
      </listOfReactants>
      <listOfProducts>
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        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_38 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000434" id="reaction_230" name="Ca binding to camR_ca1_A_CaMKII site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_35"/>
        <speciesReference species="species_1"/>
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      <listOfProducts>
        <speciesReference species="species_39"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_35 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000435" id="reaction_231" name="Ca binding to camR_ca1_A_CaMKII site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_35"/>
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      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_40"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_35 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000436" id="reaction_232" name="Ca binding to camR_ca1_A_CaMKII site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_35"/>
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      <listOfProducts>
        <speciesReference species="species_41"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_35 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000437" id="reaction_233" name="Ca binding to camR_ca1_B_CaMKII site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_36"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_39"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_36 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000438" id="reaction_234" name="Ca binding to camR_ca1_B_CaMKII site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_36"/>
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      <listOfProducts>
        <speciesReference species="species_42"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_36 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000439" id="reaction_235" name="Ca binding to camR_ca1_B_CaMKII site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_36"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_43"/>
      </listOfProducts>
      <kineticLaw>
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        <speciesReference species="species_65"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_61"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_65 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000544" id="reaction_340" name="Ca dissociation from camR_ca3_BCD_PP2B site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_65"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_60"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_65 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000545" id="reaction_341" name="Ca dissociation from camR_ca3_BCD_PP2B site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_65"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_59"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_65 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000546" id="reaction_342" name="Ca binding to camR_ca3_ABC_PP2B site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_62"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_62 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000547" id="reaction_343" name="Ca binding to camR_ca3_ABD_PP2B site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_63"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_63 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000548" id="reaction_344" name="Ca binding to camR_ca3_ACD_PP2B site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_64"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_64 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000549" id="reaction_345" name="Ca binding to camR_ca3_BCD_PP2B site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_65"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_65 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000550" id="reaction_346" name="Ca dissociating from camR_ca4_ABCD_PP2B site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_65"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000551" id="reaction_347" name="Ca dissociating from camR_ca4_ABCD_PP2B site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_64"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000552" id="reaction_348" name="Ca dissociating from camR_ca4_ABCD_PP2B site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_63"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000553" id="reaction_349" name="Ca dissociating from camR_ca4_ABCD_PP2B site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_62"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000554" id="reaction_350" name="Ca dissociation from camR_ca1_CaMKII site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_36"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_36 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction metaid="metaid_0000555" id="reaction_351" name="Ca dissociating from camT_ca3_ABC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_28 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
  </listOfReactions>
</model>
</sbml>

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