Multiscale simulation of the striatal medium spiny neuron (Mattioni & Le Novere 2013)

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Accession:150284
"… We present a new event-driven algorithm to synchronize different neuronal models, which decreases computational time and avoids superfluous synchronizations. The algorithm is implemented in the TimeScales framework. We demonstrate its use by simulating a new multiscale model of the Medium Spiny Neuron of the Neostriatum. The model comprises over a thousand dendritic spines, where the electrical model interacts with the respective instances of a biochemical model. Our results show that a multiscale model is able to exhibit changes of synaptic plasticity as a result of the interaction between electrical and biochemical signaling. …"
Reference:
1 . Mattioni M, Le Novère N (2013) Integration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatum. PLoS One 8:e66811 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Synapse;
Brain Region(s)/Organism: Striatum;
Cell Type(s): Neostriatum medium spiny direct pathway GABA cell;
Channel(s): I Na,p; I Na,t; I T low threshold; I A; I K,Ca; I CAN; I Calcium; I A, slow; I Krp; I R; I Q;
Gap Junctions:
Receptor(s):
Gene(s): Kv4.2 KCND2; Kv1.2 KCNA2; Cav1.3 CACNA1D; Cav1.2 CACNA1C; Kv2.1 KCNB1;
Transmitter(s):
Simulation Environment: NEURON; Python;
Model Concept(s): Synaptic Plasticity; Signaling pathways; Calcium dynamics; Multiscale;
Implementer(s): Mattioni, Michele [mattioni at ebi.ac.uk];
Search NeuronDB for information about:  Neostriatum medium spiny direct pathway GABA cell; I Na,p; I Na,t; I T low threshold; I A; I K,Ca; I CAN; I Calcium; I A, slow; I Krp; I R; I Q;
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        <p>This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2008 The BioModels Team.
        
        <br/>For more information see the 
        
        <a href="http://www.ebi.ac.uk/biomodels/legal.html" target="_blank">terms of use</a>.
        
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        <a href="http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&amp;pubmedid=16381960" target="_blank"> Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.</a>
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    </functionDefinition>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> species_v_22 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_22 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition id="function_12" metaid="metaid_0000022" name="function_4_Transition camT_ca2_AC to camR_ca2_AC">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> species_v_23 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_23 </ci>
              <ci> parameter_10 </ci>
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            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_13 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> species_v_28 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_28 </ci>
              <ci> parameter_10 </ci>
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            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_v_29 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_29 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_v_30 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_30 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_v_31 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_31 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
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      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> parameter_9 </ci>
          </bvar>
          <bvar>
            <ci> species_v_16 </ci>
          </bvar>
          <apply>
            <times/>
            <ci> species_v_16 </ci>
            <ci> parameter_9 </ci>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
    <functionDefinition id="function_26" metaid="metaid_0000028" name="function_4_Transition camT_ca4_ABCD to camR_ca4_ABCD">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <lambda>
          <bvar>
            <ci> parameter_10 </ci>
          </bvar>
          <bvar>
            <ci> parameter_11 </ci>
          </bvar>
          <bvar>
            <ci> parameter_12 </ci>
          </bvar>
          <bvar>
            <ci> parameter_13 </ci>
          </bvar>
          <bvar>
            <ci> parameter_14 </ci>
          </bvar>
          <bvar>
            <ci> species_v_32 </ci>
          </bvar>
          <apply>
            <divide/>
            <apply>
              <times/>
              <ci> species_v_32 </ci>
              <ci> parameter_10 </ci>
            </apply>
            <apply>
              <power/>
              <apply>
                <times/>
                <ci> parameter_11 </ci>
                <ci> parameter_12 </ci>
                <ci> parameter_13 </ci>
                <ci> parameter_14 </ci>
              </apply>
              <apply>
                <divide/>
                <cn> 1 </cn>
                <cn> 2 </cn>
              </apply>
            </apply>
          </apply>
        </lambda>
      </math>
    </functionDefinition>
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    <species compartment="compartment_0" id="species_61" initialConcentration="0" metaid="metaid_0000152" name="camR_ca2_CD_PP2B"/>
    <species compartment="compartment_0" id="species_62" initialConcentration="0" metaid="metaid_0000153" name="camR_ca3_ABC_PP2B"/>
    <species compartment="compartment_0" id="species_63" initialConcentration="0" metaid="metaid_0000154" name="camR_ca3_ABD_PP2B"/>
    <species compartment="compartment_0" id="species_64" initialConcentration="0" metaid="metaid_0000155" name="camR_ca3_ACD_PP2B"/>
    <species compartment="compartment_0" id="species_65" initialConcentration="0" metaid="metaid_0000156" name="camR_ca3_BCD_PP2B"/>
    <species compartment="compartment_0" id="species_66" initialConcentration="0" metaid="metaid_0000157" name="camR_ca4_ABCD_PP2B"/>
  </listOfSpecies>
  <listOfParameters>
    <parameter id="parameter_0" metaid="metaid_0000029" name="kon" value="1000000"/>
    <parameter constant="false" id="parameter_1" metaid="metaid_0000030" name="koffRA" value="8.32"/>
    <parameter constant="false" id="parameter_2" metaid="metaid_0000031" name="koffRB" value="0.0166"/>
    <parameter constant="false" id="parameter_3" metaid="metaid_0000032" name="koffRC" value="17.4"/>
    <parameter constant="false" id="parameter_4" metaid="metaid_0000033" name="koffRD" value="0.0145"/>
    <parameter constant="false" id="parameter_5" metaid="metaid_0000034" name="koffTA" value="2101.0101010101"/>
    <parameter constant="false" id="parameter_6" metaid="metaid_0000035" name="koffTB" value="4.19191919191919"/>
    <parameter constant="false" id="parameter_7" metaid="metaid_0000036" name="koffTC" value="4393.93939393939"/>
    <parameter constant="false" id="parameter_8" metaid="metaid_0000037" name="koffTD" value="3.66161616161616"/>
    <parameter id="parameter_9" metaid="metaid_0000038" name="kRT" value="1000000"/>
    <parameter constant="false" id="parameter_10" metaid="metaid_0000039" name="kTR" value="48.3792936623125"/>
    <parameter id="parameter_11" metaid="metaid_0000040" name="cA" value="0.00396"/>
    <parameter id="parameter_12" metaid="metaid_0000041" name="cB" value="0.00396"/>
    <parameter id="parameter_13" metaid="metaid_0000042" name="cC" value="0.00396"/>
    <parameter id="parameter_14" metaid="metaid_0000043" name="cD" value="0.00396"/>
    <parameter id="parameter_15" metaid="metaid_0000044" name="konCaMKII" value="3200000"/>
    <parameter id="parameter_16" metaid="metaid_0000045" name="koffCaMKII" value="0.343"/>
    <parameter id="parameter_17" metaid="metaid_0000046" name="konPP2B" value="46000000"/>
    <parameter id="parameter_18" metaid="metaid_0000047" name="koffPP2B" value="0.4"/>
    <parameter constant="false" id="parameter_19" metaid="metaid_0000048" name="free_camR_ca3_total" value="0"/>
    <parameter constant="false" id="parameter_20" metaid="metaid_0000049" name="free_camT_ca3_total" value="0"/>
    <parameter constant="false" id="parameter_21" metaid="metaid_0000050" name="free_cam_ca3_total" value="0"/>
    <parameter constant="false" id="parameter_22" metaid="metaid_0000051" name="cam_ca4_total" value="0"/>
    <parameter constant="false" id="parameter_23" metaid="metaid_0000052" name="CaMKII_camR_ca1" value="0"/>
    <parameter constant="false" id="parameter_24" metaid="metaid_0000053" name="CaMKII_camR_ca2" value="0"/>
    <parameter constant="false" id="parameter_25" metaid="metaid_0000054" name="CaMKII_camR_ca3" value="0"/>
    <parameter constant="false" id="parameter_26" metaid="metaid_0000055" name="total_CaMKII_bound" value="0"/>
    <parameter constant="false" id="parameter_27" metaid="metaid_0000056" name="total CaMKII" value="7e-05"/>
    <parameter constant="false" id="parameter_28" metaid="metaid_0000057" name="CaMKIIbar" value="0"/>
    <parameter constant="false" id="parameter_29" metaid="metaid_0000058" name="PP2B_camR_ca1" value="0"/>
    <parameter constant="false" id="parameter_30" metaid="metaid_0000059" name="PP2B_camR_ca2" value="0"/>
    <parameter constant="false" id="parameter_31" metaid="metaid_0000060" name="PP2B_camR_ca3" value="0"/>
    <parameter constant="false" id="parameter_32" metaid="metaid_0000061" name="total_PP2B_bound" value="0"/>
    <parameter constant="false" id="parameter_33" metaid="metaid_0000062" name="total PP2B" value="1.6e-06"/>
    <parameter constant="false" id="parameter_34" metaid="metaid_0000063" name="PP2Bbar" value="0"/>
    <parameter constant="false" id="parameter_35" metaid="metaid_0000064" name="camR_unbound" value="9.7e-12"/>
    <parameter constant="false" id="parameter_36" metaid="metaid_0000065" name="total camR" value="9.7e-12"/>
    <parameter constant="false" id="parameter_37" metaid="metaid_0000066" name="total camT" value="2e-07"/>
    <parameter constant="false" id="parameter_38" metaid="metaid_0000067" name="Rbar" value="4.84976478640786e-05"/>
    <parameter constant="false" id="parameter_39" metaid="metaid_0000068" name="cam_ca3_total" value="0"/>
    <parameter constant="false" id="parameter_40" metaid="metaid_0000069" name="free_camR_ca2_total" value="0"/>
    <parameter constant="false" id="parameter_41" metaid="metaid_0000070" name="free_camT_ca2_total" value="0"/>
    <parameter constant="false" id="parameter_42" metaid="metaid_0000071" name="free_cam_ca2_total" value="0"/>
    <parameter constant="false" id="parameter_43" metaid="metaid_0000072" name="cam_ca2_total" value="0"/>
    <parameter constant="false" id="parameter_44" metaid="metaid_0000073" name="free_cam_ca1_total" value="0"/>
    <parameter constant="false" id="parameter_45" metaid="metaid_0000074" name="cam_ca1_total" value="0"/>
    <parameter constant="false" id="parameter_46" metaid="metaid_0000075" name="cam_ca0_total" value="2.000097e-07"/>
    <parameter constant="false" id="parameter_47" metaid="metaid_0000076" name="cam_total" value="2.000097e-07"/>
    <parameter constant="false" id="parameter_48" metaid="metaid_0000077" name="moles_bound_ca_per_moles_cam" value="0"/>
    <parameter id="parameter_49" metaid="metaid_0000078" name="L" value="20670"/>
    <parameter id="parameter_50" metaid="metaid_0000079" name="KRA" value="8.32e-06"/>
    <parameter id="parameter_51" metaid="metaid_0000080" name="KRB" value="1.66e-08"/>
    <parameter id="parameter_52" metaid="metaid_0000081" name="KRC" value="1.74e-05"/>
    <parameter id="parameter_53" metaid="metaid_0000082" name="KRD" value="1.45e-08"/>
    
    
    
    
    <parameter constant="false" id="parameter_58" metaid="metaid_0000087" name="epsilon" value="4.84976478640786e-05"/>
    <parameter constant="false" id="parameter_59" metaid="metaid_0000088" name="ybar" value="0"/>
    <parameter constant="false" id="parameter_60" metaid="metaid_0000089" name="ybar/(1-ybar)" value="0"/>
  </listOfParameters>
  <listOfRules>
    <assignmentRule metaid="metaid_0000158" variable="parameter_1">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_50 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000159" variable="parameter_20">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_28 </ci>
          <ci> species_29 </ci>
          <ci> species_30 </ci>
          <ci> species_31 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000160" variable="parameter_2">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_51 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000161" variable="parameter_3">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_52 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000162" variable="parameter_4">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> parameter_53 </ci>
          <ci> parameter_0 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000163" variable="parameter_5">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_1 </ci>
          <ci> parameter_11 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000164" variable="parameter_6">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_2 </ci>
          <ci> parameter_12 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000165" variable="parameter_7">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_3 </ci>
          <ci> parameter_13 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000166" variable="parameter_8">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_4 </ci>
          <ci> parameter_14 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000167" variable="parameter_10">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_9 </ci>
          <ci> parameter_49 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000168" variable="parameter_19">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_12 </ci>
          <ci> species_13 </ci>
          <ci> species_14 </ci>
          <ci> species_15 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000169" variable="parameter_21">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_19 </ci>
          <ci> parameter_20 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000170" variable="parameter_22">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_16 </ci>
          <ci> species_32 </ci>
          <ci> species_49 </ci>
          <ci> species_66 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000171" variable="parameter_23">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_35 </ci>
          <ci> species_36 </ci>
          <ci> species_37 </ci>
          <ci> species_38 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000172" variable="parameter_25">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_45 </ci>
          <ci> species_46 </ci>
          <ci> species_47 </ci>
          <ci> species_48 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000173" variable="parameter_24">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_39 </ci>
          <ci> species_40 </ci>
          <ci> species_41 </ci>
          <ci> species_42 </ci>
          <ci> species_43 </ci>
          <ci> species_44 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000174" variable="parameter_26">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_34 </ci>
          <ci> parameter_23 </ci>
          <ci> parameter_24 </ci>
          <ci> parameter_25 </ci>
          <ci> species_49 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000175" variable="parameter_27">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_26 </ci>
          <ci> species_33 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000176" variable="parameter_28">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_26 </ci>
          <ci> parameter_27 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000177" variable="parameter_29">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_52 </ci>
          <ci> species_53 </ci>
          <ci> species_54 </ci>
          <ci> species_55 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000178" variable="parameter_30">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_56 </ci>
          <ci> species_57 </ci>
          <ci> species_58 </ci>
          <ci> species_59 </ci>
          <ci> species_60 </ci>
          <ci> species_61 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000179" variable="parameter_31">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_62 </ci>
          <ci> species_63 </ci>
          <ci> species_64 </ci>
          <ci> species_65 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000180" variable="parameter_32">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_51 </ci>
          <ci> parameter_29 </ci>
          <ci> parameter_30 </ci>
          <ci> parameter_31 </ci>
          <ci> species_66 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000181" variable="parameter_35">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_0 </ci>
          <ci> species_2 </ci>
          <ci> species_3 </ci>
          <ci> species_4 </ci>
          <ci> species_5 </ci>
          <ci> species_6 </ci>
          <ci> species_7 </ci>
          <ci> species_8 </ci>
          <ci> species_9 </ci>
          <ci> species_10 </ci>
          <ci> species_11 </ci>
          <ci> species_12 </ci>
          <ci> species_13 </ci>
          <ci> species_14 </ci>
          <ci> species_15 </ci>
          <ci> species_16 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000182" variable="parameter_33">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_32 </ci>
          <ci> species_50 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000183" variable="parameter_34">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_32 </ci>
          <ci> parameter_33 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000184" variable="parameter_37">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_17 </ci>
          <ci> species_18 </ci>
          <ci> species_19 </ci>
          <ci> species_20 </ci>
          <ci> species_21 </ci>
          <ci> species_22 </ci>
          <ci> species_23 </ci>
          <ci> species_24 </ci>
          <ci> species_25 </ci>
          <ci> species_26 </ci>
          <ci> species_27 </ci>
          <ci> species_28 </ci>
          <ci> species_29 </ci>
          <ci> species_30 </ci>
          <ci> species_31 </ci>
          <ci> species_32 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000185" variable="parameter_36">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_35 </ci>
          <ci> parameter_26 </ci>
          <ci> parameter_32 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000186" variable="parameter_39">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_25 </ci>
          <ci> parameter_31 </ci>
          <ci> parameter_21 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000187" variable="parameter_38">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_36 </ci>
          <apply>
            <plus/>
            <ci> parameter_36 </ci>
            <ci> parameter_37 </ci>
          </apply>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000188" variable="parameter_40">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_6 </ci>
          <ci> species_7 </ci>
          <ci> species_8 </ci>
          <ci> species_9 </ci>
          <ci> species_10 </ci>
          <ci> species_11 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000189" variable="parameter_41">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_22 </ci>
          <ci> species_23 </ci>
          <ci> species_24 </ci>
          <ci> species_25 </ci>
          <ci> species_26 </ci>
          <ci> species_27 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000190" variable="parameter_42">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_40 </ci>
          <ci> parameter_41 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000191" variable="parameter_43">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_42 </ci>
          <ci> parameter_24 </ci>
          <ci> parameter_30 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000192" variable="parameter_44">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_2 </ci>
          <ci> species_3 </ci>
          <ci> species_4 </ci>
          <ci> species_5 </ci>
          <ci> species_18 </ci>
          <ci> species_19 </ci>
          <ci> species_20 </ci>
          <ci> species_21 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000193" variable="parameter_45">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_44 </ci>
          <ci> parameter_23 </ci>
          <ci> parameter_29 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000194" variable="parameter_46">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> species_0 </ci>
          <ci> species_17 </ci>
          <ci> species_34 </ci>
          <ci> species_51 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000195" variable="parameter_47">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <plus/>
          <ci> parameter_46 </ci>
          <ci> parameter_45 </ci>
          <ci> parameter_43 </ci>
          <ci> parameter_39 </ci>
          <ci> parameter_22 </ci>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000196" variable="parameter_48">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <apply>
            <plus/>
            <apply>
              <times/>
              <cn> 4 </cn>
              <ci> parameter_22 </ci>
            </apply>
            <apply>
              <times/>
              <cn> 3 </cn>
              <ci> parameter_39 </ci>
            </apply>
            <apply>
              <times/>
              <cn> 2 </cn>
              <ci> parameter_43 </ci>
            </apply>
            <ci> parameter_45 </ci>
          </apply>
          <ci> parameter_47 </ci>
        </apply>
      </math>
    </assignmentRule>
    
    
    
    
    <assignmentRule metaid="metaid_0000201" variable="parameter_58">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> species_0 </ci>
          <apply>
            <plus/>
            <ci> species_0 </ci>
            <ci> species_17 </ci>
          </apply>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000202" variable="parameter_59">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_48 </ci>
          <cn> 4 </cn>
        </apply>
      </math>
    </assignmentRule>
    <assignmentRule metaid="metaid_0000203" variable="parameter_60">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <divide/>
          <ci> parameter_59 </ci>
          <apply>
            <minus/>
            <cn> 1 </cn>
            <ci> parameter_59 </ci>
          </apply>
        </apply>
      </math>
    </assignmentRule>
  </listOfRules>
  <listOfReactions>
    <reaction id="reaction_0" metaid="metaid_0000204" name="Ca binding to camR site A" reversible="false" sboTerm="SBO:0000177">
      <annotation>
        <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
          <rdf:Description rdf:about="#metaid_0000204">
            <bqbiol:isVersionOf>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005509"/>
              </rdf:Bag>
            </bqbiol:isVersionOf>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
      <listOfReactants>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_0 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_1" metaid="metaid_0000205" name="Ca binding to camR site B" reversible="false" sboTerm="SBO:0000177">
      <annotation>
        <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
          <rdf:Description rdf:about="#metaid_0000205">
            <bqbiol:isVersionOf>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005509"/>
              </rdf:Bag>
            </bqbiol:isVersionOf>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
      <listOfReactants>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_0 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_2" metaid="metaid_0000206" name="Ca binding to camR site C" reversible="false" sboTerm="SBO:0000177">
      <annotation>
        <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
          <rdf:Description rdf:about="#metaid_0000206">
            <bqbiol:isVersionOf>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005509"/>
              </rdf:Bag>
            </bqbiol:isVersionOf>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
      <listOfReactants>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_0 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_3" metaid="metaid_0000207" name="Ca binding to camR site D" reversible="false" sboTerm="SBO:0000177">
      <annotation>
        <rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
          <rdf:Description rdf:about="#metaid_0000207">
            <bqbiol:isVersionOf>
              <rdf:Bag>
                <rdf:li rdf:resource="urn:miriam:obo.go:GO%3A0005509"/>
              </rdf:Bag>
            </bqbiol:isVersionOf>
          </rdf:Description>
        </rdf:RDF>
      </annotation>
      <listOfReactants>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_0 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_4" metaid="metaid_0000208" name="Ca dissociating from camR_ca1_A site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_2"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_2 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_5" metaid="metaid_0000209" name="Ca dissociating from camR_ca1_B site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_3"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_3 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_6" metaid="metaid_0000210" name="Ca dissociating from camR_ca1_C site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_4"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_4 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_7" metaid="metaid_0000211" name="Ca dissociating from camR_ca1_D site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_5"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_5 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_8" metaid="metaid_0000212" name="Ca binding to camR_ca1_A site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_2"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_2 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_9" metaid="metaid_0000213" name="Ca binding to camR_ca1_A site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_2"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_2 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_10" metaid="metaid_0000214" name="Ca binding to camR_ca1_A site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_2"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_2 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_11" metaid="metaid_0000215" name="Ca binding to camR_ca1_B site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_3"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_3 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_12" metaid="metaid_0000216" name="Ca binding to camR_ca1_B site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_3"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_3 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_13" metaid="metaid_0000217" name="Ca binding to camR_ca1_B site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_3"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_3 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_14" metaid="metaid_0000218" name="Ca binding to camR_ca1_C site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_4"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_4 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_15" metaid="metaid_0000219" name="Ca binding to camR_ca1_C site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_4"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_4 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_16" metaid="metaid_0000220" name="Ca binding to camR_ca1_C site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_4"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_4 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_17" metaid="metaid_0000221" name="Ca binding to camR_ca1_D site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_5"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_5 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_18" metaid="metaid_0000222" name="Ca binding to camR_ca1_D site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_5"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_5 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_19" metaid="metaid_0000223" name="Ca binding to camR_ca1_D site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_5"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_5 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_20" metaid="metaid_0000224" name="Ca dissociating from camR_ca2_AB site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_6"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_6 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_21" metaid="metaid_0000225" name="Ca dissociating from camR_ca2_AC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_7"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_7 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_22" metaid="metaid_0000226" name="Ca dissociating from camR_ca2_AD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_8"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_8 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_23" metaid="metaid_0000227" name="Ca dissociating from camR_ca2_AB site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_6"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_6 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_24" metaid="metaid_0000228" name="Ca dissociating from camR_ca2_BC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_9"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_9 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_25" metaid="metaid_0000229" name="Ca dissociating from camR_ca2_BD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_10"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_10 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_26" metaid="metaid_0000230" name="Ca dissociating from camR_ca2_AC site A " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_7"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_7 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_27" metaid="metaid_0000231" name="Ca dissociating from camR_ca2_BC site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_9"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_9 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_28" metaid="metaid_0000232" name="Ca dissociating from camR_ca2_CD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_11"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_11 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_29" metaid="metaid_0000233" name="Ca dissociating from camR_ca2_AD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_8"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_8 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_30" metaid="metaid_0000234" name="Ca dissociating from camR_ca2_BD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_10"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_10 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_31" metaid="metaid_0000235" name="Ca dissociating from camR_ca2_CD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_11"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_11 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_32" metaid="metaid_0000236" name="Ca binding to camR_ca2_AB site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_6"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_6 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_33" metaid="metaid_0000237" name="Ca binding to camR_ca2_AB site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_6"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_6 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_34" metaid="metaid_0000238" name="Ca binding to camR_ca2_AC site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_7"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_7 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_35" metaid="metaid_0000239" name="Ca binding to camR_ca2_AC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_7"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_7 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_36" metaid="metaid_0000240" name="Ca binding to camR_ca2_AD site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_8"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_8 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_37" metaid="metaid_0000241" name="Ca binding to camR_ca2_AD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_8"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_8 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_38" metaid="metaid_0000242" name="Ca binding to camR_ca2_BC site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_9"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_9 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_39" metaid="metaid_0000243" name="Ca binding to camR_ca2_BC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_9"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_9 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_40" metaid="metaid_0000244" name="Ca binding to camR_ca2_BD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_10"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_10 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_41" metaid="metaid_0000245" name="Ca binding to camR_ca2_BD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_10"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_10 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_42" metaid="metaid_0000246" name="Ca binding to camR_ca2_CD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_11"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_11 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_43" metaid="metaid_0000247" name="Ca binding to camR_ca2_CD site B " reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_11"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_11 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_44" metaid="metaid_0000248" name="Ca dissociating from camR_ca3_ABC site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_12"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_12 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_45" metaid="metaid_0000249" name="Ca dissociating from camR_ca3_ABC site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_12"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_12 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_46" metaid="metaid_0000250" name="Ca dissociating from camR_ca3_ABC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_12"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_12 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_47" metaid="metaid_0000251" name="Ca dissociating from camR_ca3_ABD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_13"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_13 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_48" metaid="metaid_0000252" name="Ca dissociating from camR_ca3_ABD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_13"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_13 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_49" metaid="metaid_0000253" name="Ca dissociating from camR_ca3_ABD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_13"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_13 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_50" metaid="metaid_0000254" name="Ca dissociating from camR_ca3_ACD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_14"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_14 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_51" metaid="metaid_0000255" name="Ca dissociating from camR_ca3_ACD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_14"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_14 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_52" metaid="metaid_0000256" name="Ca dissociating from camR_ca3_ACD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_14"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_14 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_53" metaid="metaid_0000257" name="Ca dissociating from camR_ca3_BCD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_15"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_15 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_54" metaid="metaid_0000258" name="Ca dissociating from camR_ca3_BCD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_15"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_15 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_55" metaid="metaid_0000259" name="Ca dissociating from camR_ca3_BCD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_15"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_15 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_56" metaid="metaid_0000260" name="Ca binding to camR_ca3_ABC site D " reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_12"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_12 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_57" metaid="metaid_0000261" name="Ca binding to camR_ca3_ABD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_13"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_13 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_58" metaid="metaid_0000262" name="Ca binding to camR_ca3_ACD site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_14"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_14 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_59" metaid="metaid_0000263" name="Ca binding to camR_ca3_BCD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_15"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_15 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_60" metaid="metaid_0000264" name="Ca dissociating from camR_ca4_ABCD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_16"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_16 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_61" metaid="metaid_0000265" name="Ca dissociating from camR_ca4_ABCD site C " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_16"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_16 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_62" metaid="metaid_0000266" name="Ca dissociating from camR_ca4_ABCD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_16"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_16 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_63" metaid="metaid_0000267" name="Ca dissociating from camR_ca4_ABCD site A " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_16"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_16 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_64" metaid="metaid_0000268" name="Ca binding to camT site A " reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_18"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_17 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_65" metaid="metaid_0000269" name="Ca binding to camT site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_19"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_17 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_66" metaid="metaid_0000270" name="Ca binding to camT site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_20"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_17 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_67" metaid="metaid_0000271" name="Ca binding to camT site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_21"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_17 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_68" metaid="metaid_0000272" name="Ca dissociating from camT_ca1_A site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_18"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_18 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_69" metaid="metaid_0000273" name="Ca dissociating from camT_ca1_B site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_19"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_19 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_70" metaid="metaid_0000274" name="Ca dissociating from camT_ca1_C site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_20"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_20 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_71" metaid="metaid_0000275" name="Ca dissociating from camT_ca1_D site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_21"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_17"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_21 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_72" metaid="metaid_0000276" name="Ca binding to camT_ca1_A site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_18"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_18 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_73" metaid="metaid_0000277" name="Ca binding to camT_ca1_A site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_18"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_18 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_74" metaid="metaid_0000278" name="Ca binding to camT_ca1_A site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_18"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_18 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_75" metaid="metaid_0000279" name="Ca binding to camT_ca1_B site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_19"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_19 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_76" metaid="metaid_0000280" name="Ca binding to camT_ca1_B site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_19"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_19 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_77" metaid="metaid_0000281" name="Ca binding to camT_ca1_B site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_19"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_19 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_78" metaid="metaid_0000282" name="Ca binding to camT_ca1_C site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_20"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_20 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_79" metaid="metaid_0000283" name="Ca binding to camT_ca1_C site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_20"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_20 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_80" metaid="metaid_0000284" name="Ca binding to camT_ca1_C site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_20"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_20 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_81" metaid="metaid_0000285" name="Ca binding to camT_ca1_D site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_21"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_21 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_82" metaid="metaid_0000286" name="Ca binding to camT_ca1_D site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_21"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_21 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_83" metaid="metaid_0000287" name="Ca binding to camT_ca1_D site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_21"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_21 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_84" metaid="metaid_0000288" name="Ca dissociating from camT_ca2_AB site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_22"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_19"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_22 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_85" metaid="metaid_0000289" name="Ca dissociating from camT_ca2_AB site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_22"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_18"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_22 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_86" metaid="metaid_0000290" name="Ca dissociating from camT_ca2_AC site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_23"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_20"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_23 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_87" metaid="metaid_0000291" name="Ca dissociating from camT_ca2_AC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_23"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_18"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_23 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_88" metaid="metaid_0000292" name="Ca dissociating from camT_ca2_AD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_24"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_21"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_24 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_89" metaid="metaid_0000293" name="Ca dissociating from camT_ca2_AD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_24"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_18"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_24 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_90" metaid="metaid_0000294" name="Ca dissociating from camT_ca2_BC site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_25"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_20"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_25 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_91" metaid="metaid_0000295" name="Ca dissociating from camT_ca2_BC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_25"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_19"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_25 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_92" metaid="metaid_0000296" name="Ca dissociating from camT_ca2_BD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_26"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_21"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_26 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_93" metaid="metaid_0000297" name="Ca dissociating from camT_ca2_BD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_26"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_19"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_26 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_94" metaid="metaid_0000298" name="Ca dissociating from camT_ca2_CD site C " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_27"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_21"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_27 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_95" metaid="metaid_0000299" name="Ca dissociating from camT_ca2_CD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_27"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_20"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_27 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_96" metaid="metaid_0000300" name="Ca binding to camT_ca2_AB site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_22"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_22 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_97" metaid="metaid_0000301" name="Ca binding to camT_ca2_AB site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_22"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_22 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_98" metaid="metaid_0000302" name="Ca binding to camT_ca2_AC site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_23 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_99" metaid="metaid_0000303" name="Ca binding to camT_ca2_AC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_23 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_100" metaid="metaid_0000304" name="Ca binding to camT_ca2_AD site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_24 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_101" metaid="metaid_0000305" name="Ca binding to camT_ca2_AD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_24 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_102" metaid="metaid_0000306" name="Ca binding to camT_ca2_BC site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_25 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_103" metaid="metaid_0000307" name="Ca binding to camT_ca2_BC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_25 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_104" metaid="metaid_0000308" name="Ca binding to camT_ca2_BD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_26 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_105" metaid="metaid_0000309" name="Ca binding to camT_ca2_BD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_26 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_106" metaid="metaid_0000310" name="Ca binding to camT_ca2_CD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_27 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_107" metaid="metaid_0000311" name="Ca binding to camT_ca2_CD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_27 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_108" metaid="metaid_0000312" name="Ca dissociating from camT_ca3_ABC site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_28 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_109" metaid="metaid_0000313" name="Ca dissociating from camT_ca3_ABC site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_28 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_110" metaid="metaid_0000314" name="Ca dissociating from camT_ca3_ABD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_29 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_111" metaid="metaid_0000315" name="Ca dissociating from camT_ca3_ABD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_29 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_112" metaid="metaid_0000316" name="Ca dissociating from camT_ca3_ABD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_29 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_113" metaid="metaid_0000317" name="Ca dissociating from camT_ca3_ACD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_30 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_114" metaid="metaid_0000318" name="Ca dissociating from camT_ca3_ACD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_30 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_115" metaid="metaid_0000319" name="Ca dissociating from camT_ca3_ACD site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_30 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_116" metaid="metaid_0000320" name="Ca dissociating from camT_ca3_BCD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_31 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_117" metaid="metaid_0000321" name="Ca dissociating from camT_ca3_BCD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_31 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_118" metaid="metaid_0000322" name="Ca dissociating from camT_ca3_BCD site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_31 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_119" metaid="metaid_0000323" name="Ca binding to camT_ca3_ABC site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_28"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_28 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_120" metaid="metaid_0000324" name="Ca binding to camT_ca3_ABD site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_29"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_29 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_121" metaid="metaid_0000325" name="Ca binding to camT_ca3_ACD site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_30"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_30 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_122" metaid="metaid_0000326" name="Ca binding to camT_ca3_BCD site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_31"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_31 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_123" metaid="metaid_0000327" name="Ca dissociating from camT_ca4_ABCD site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_8 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_124" metaid="metaid_0000328" name="Ca dissociating from camT_ca4_ABCD site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_125" metaid="metaid_0000329" name="Ca dissociating from camT_ca4_ABCD site B " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_6 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_126" metaid="metaid_0000330" name="Ca dissociating from camT_ca4_ABCD site A " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_5 </ci>
            <ci> species_32 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_127" metaid="metaid_0000331" name="Transition camR to camT" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_0"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_17"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_0 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_128" metaid="metaid_0000332" name="Transition camT to camR" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_17"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_10 </ci>
            <ci> species_17 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_129" metaid="metaid_0000333" name="Transition camR_ca1_A to camT_ca1_A" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_2"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_18"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_2 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_130" metaid="metaid_0000334" name="Transition camR_ca1_B to camT_ca1_B" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_3"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_19"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_3 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_131" metaid="metaid_0000335" name="Transition camR_ca1_C to camT_ca1_C" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_4"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_20"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_4 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_132" metaid="metaid_0000336" name="Transition camR_ca1_D to camT_ca1_D" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_5"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_21"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_9 </ci>
            <ci> species_5 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_133" metaid="metaid_0000337" name="Transition camT_ca1_A to camR_ca1_A" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_18"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_1 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> species_18 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_134" metaid="metaid_0000338" name="Transition camT_ca1_B to camR_ca1_B" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_19"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_2 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> species_19 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_135" metaid="metaid_0000339" name="Transition camT_ca1_C to camR_ca1_C" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_20"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_3 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_13 </ci>
              <ci> species_20 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_136" metaid="metaid_0000340" name="Transition camT_ca1_D to camR_ca1_D" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_21"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_4 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_14 </ci>
              <ci> species_21 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_137" metaid="metaid_0000341" name="Transition camR_ca2_AB to camT_ca2_AB" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_6"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_5 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_9 </ci>
              <ci> species_6 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_138" metaid="metaid_0000342" name="Transition camR_ca2_AC to camT_ca2_AC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_7"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_23"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_6 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_9 </ci>
              <ci> species_7 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_139" metaid="metaid_0000343" name="Transition camR_ca2_AD to camT_ca2_AD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_8"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_24"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_7 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_8 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_140" metaid="metaid_0000344" name="Transition camR_ca2_BC to camT_ca2_BC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_9"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_25"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_8 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_9 </ci>
              <ci> species_9 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_141" metaid="metaid_0000345" name="Transition camR_ca2_BD to camT_ca2_BD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_10"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_26"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_9 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_10 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_142" metaid="metaid_0000346" name="Transition camR_ca2_CD to camT_ca2_CD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_11"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_27"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_10 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_11 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_143" metaid="metaid_0000347" name="Transition camT_ca2_AB to camR_ca2_AB" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_22"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_11 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> species_22 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_144" metaid="metaid_0000348" name="Transition camT_ca2_AC to camR_ca2_AC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_23"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_12 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> species_23 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_145" metaid="metaid_0000349" name="Transition camT_ca2_AD to camR_ca2_AD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_24"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_13 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_14 </ci>
              <ci> species_24 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_146" metaid="metaid_0000350" name="Transition camT_ca2_BC to camR_ca2_BC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_25"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_14 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> species_25 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_147" metaid="metaid_0000351" name="Transition camT_ca2_BD to camR_ca2_BD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_26"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_15 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> species_26 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_148" metaid="metaid_0000352" name="Transition camT_ca2_CD to camR_ca2_CD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_27"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_16 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_27 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_149" metaid="metaid_0000353" name="Transition camR_ca3_ABC to camT_ca3_ABC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_12"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_28"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_17 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_9 </ci>
              <ci> species_12 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_150" metaid="metaid_0000354" name="Transition camR_ca3_ABD to camT_ca3_ABD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_13"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_29"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_18 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_13 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_151" metaid="metaid_0000355" name="Transition camR_ca3_ACD to camT_ca3_ACD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_14"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_30"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_19 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_14 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_152" metaid="metaid_0000356" name="Transition camR_ca3_BCD to camT_ca3_BCD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_15"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_31"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_20 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_15 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_153" metaid="metaid_0000357" name="Transition camT_ca3_ABC to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_21 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> species_28 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_154" metaid="metaid_0000358" name="Transition camT_ca3_ABD to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_29"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_22 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_14 </ci>
              <ci> species_29 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_155" metaid="metaid_0000359" name="Transition camT_ca3_ACD to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_30"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_23 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_30 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_156" metaid="metaid_0000360" name="Transition camT_ca3_BCD to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_31"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_24 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_31 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_157" metaid="metaid_0000361" name="Transition camR_ca4_ABCD to camT_ca4_ABCD" reversible="false" sboTerm="SBO:0000181">
      <listOfReactants>
        <speciesReference species="species_16"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_32"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_25 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> parameter_9 </ci>
              <ci> species_16 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_158" metaid="metaid_0000362" name="Transition camT_ca4_ABCD to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_32"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <apply>
              <ci> function_26 </ci>
              <ci> parameter_10 </ci>
              <ci> parameter_11 </ci>
              <ci> parameter_12 </ci>
              <ci> parameter_13 </ci>
              <ci> parameter_14 </ci>
              <ci> species_32 </ci>
            </apply>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_159" metaid="metaid_0000363" name="CaMKII binding to camR" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_0"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_0 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_160" metaid="metaid_0000364" name="CaMKII binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_2"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_35"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_2 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_161" metaid="metaid_0000365" name="CaMKII binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_3"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_36"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_3 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_162" metaid="metaid_0000366" name="CaMKII binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_4"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_37"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_4 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_163" metaid="metaid_0000367" name="CaMKII binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_5"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_38"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_5 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_164" metaid="metaid_0000368" name="CaMKII binding to camR_ca2_AB" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_6"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_39"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_6 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_165" metaid="metaid_0000369" name="CaMKII binding to camR_ca2_AC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_7"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_40"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_7 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_166" metaid="metaid_0000370" name="CaMKII binding to camR_ca2_AD" reversible="false">
      <listOfReactants>
        <speciesReference species="species_8"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_41"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_8 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_167" metaid="metaid_0000371" name="CaMKII binding to camR_ca2_BC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_9"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_42"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_9 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_168" metaid="metaid_0000372" name="CaMKII binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_10"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_43"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_10 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_169" metaid="metaid_0000373" name="CaMKII binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_11"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_44"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_11 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_170" metaid="metaid_0000374" name="CaMKII binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_12"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_45"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_12 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_171" metaid="metaid_0000375" name="CaMKII binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_13"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_46"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_13 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_172" metaid="metaid_0000376" name="CaMKII binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_14"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_47"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_14 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_173" metaid="metaid_0000377" name="CaMKII binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_15"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_48"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_15 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_174" metaid="metaid_0000378" name="CaMKII binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_16"/>
        <speciesReference species="species_33"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_49"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_15 </ci>
            <ci> species_16 </ci>
            <ci> species_33 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_175" metaid="metaid_0000379" name="CaMKII dissociation from camR" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_34"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_34 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_176" metaid="metaid_0000380" name="CaMKII dissociation from camR_ca1_A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_35"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_35 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_177" metaid="metaid_0000381" name="CaMKII dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_36"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_36 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_178" metaid="metaid_0000382" name="CaMKII dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_37"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_37 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_179" metaid="metaid_0000383" name="CaMKII dissociation from camR_ca1_D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_38"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_38 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_180" metaid="metaid_0000384" name="CaMKII dissociation from camR_ca2_AB" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_39"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_39 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_181" metaid="metaid_0000385" name="CaMKII dissociation from camR_ca2_AC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_40"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_40 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_182" metaid="metaid_0000386" name="CaMKII dissociation from camR_ca2_AD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_41"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_41 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_183" metaid="metaid_0000387" name="CaMKII dissociation from camR_ca2_BC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_42"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_42 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_184" metaid="metaid_0000388" name="CaMKII dissociation from camR_ca2_BD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_43"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_43 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_185" metaid="metaid_0000389" name="CaMKII dissociation from camR_ca2_CD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_44"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_44 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_186" metaid="metaid_0000390" name="CaMKII dissociation from camR_ca3_ABC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_45"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_45 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_187" metaid="metaid_0000391" name="CaMKII dissociation from camR_ca3_ABD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_46"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_46 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_188" metaid="metaid_0000392" name="CaMKII dissociation from camR_ca3_ACD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_47"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_47 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_189" metaid="metaid_0000393" name="CaMKII dissociation from camR_ca3_BCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_48"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_48 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_190" metaid="metaid_0000394" name="CaMKII dissociation from camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_49"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
        <speciesReference species="species_33"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_16 </ci>
            <ci> species_49 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_191" metaid="metaid_0000395" name="PP2B binding to camR" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_0"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_51"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_0 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_192" metaid="metaid_0000396" name="PP2B binding to camR_ca1_A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_2"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_52"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_2 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_193" metaid="metaid_0000397" name="PP2B binding to camR_ca1_B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_3"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_53"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_3 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_194" metaid="metaid_0000398" name="PP2B binding to camR_ca1_C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_4"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_54"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_4 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_195" metaid="metaid_0000399" name="PP2B binding to camR_ca1_D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_5"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_55"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_5 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_196" metaid="metaid_0000400" name="PP2B binding to camR_ca2_AB" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_6"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_56"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_6 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_197" metaid="metaid_0000401" name="PP2B binding to camR_ca2_AC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_7"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_57"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_7 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_198" metaid="metaid_0000402" name="PP2B binding to camR_ca2_AD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_8"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_58"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_8 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_199" metaid="metaid_0000403" name="PP2B binding to camR_ca2_BC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_9"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_59"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_9 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_200" metaid="metaid_0000404" name="PP2B binding to camR_ca2_BD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_10"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_60"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_10 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_201" metaid="metaid_0000405" name="PP2B binding to camR_ca2_CD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_11"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_61"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_11 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_202" metaid="metaid_0000406" name="PP2B binding to camR_ca3_ABC" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_12"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_62"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_12 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_203" metaid="metaid_0000407" name="PP2B binding to camR_ca3_ABD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_13"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_63"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_13 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_204" metaid="metaid_0000408" name="PP2B binding to camR_ca3_ACD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_14"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_64"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_14 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_205" metaid="metaid_0000409" name="PP2B binding to camR_ca3_BCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_15"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_65"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_15 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_206" metaid="metaid_0000410" name="PP2B binding to camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_16"/>
        <speciesReference species="species_50"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_17 </ci>
            <ci> species_16 </ci>
            <ci> species_50 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_207" metaid="metaid_0000411" name="PP2B dissociation from camR" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_51"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_0"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_51 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_208" metaid="metaid_0000412" name="PP2B dissociation from camR_ca1_A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_52"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_2"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_52 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_209" metaid="metaid_0000413" name="PP2B dissociation from camR_ca1_B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_53"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_3"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_53 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_210" metaid="metaid_0000414" name="PP2B dissociation from camR_ca1_C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_54"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_4"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_54 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_211" metaid="metaid_0000415" name="PP2B dissociation from camR_ca1_D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_55"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_5"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_55 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_212" metaid="metaid_0000416" name="PP2B dissociation from camR_ca2_AB" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_56"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_6"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_56 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_213" metaid="metaid_0000417" name="PP2B dissociation from camR_ca2_AC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_57"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_7"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_57 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_214" metaid="metaid_0000418" name="PP2B dissociation from camR_ca2_AD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_58"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_8"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_58 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_215" metaid="metaid_0000419" name="PP2B dissociation from camR_ca2_BC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_59"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_9"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_59 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_216" metaid="metaid_0000420" name="PP2B dissociation from camR_ca2_BD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_60"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_10"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_60 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_217" metaid="metaid_0000421" name="PP2B dissociation from camR_ca2_CD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_61"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_11"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_61 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_218" metaid="metaid_0000422" name="PP2B dissociation from camR_ca3_ABC" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_62"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_12"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_62 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_219" metaid="metaid_0000423" name="PP2B dissociation from camR_ca3_ABD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_63"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_13"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_63 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_220" metaid="metaid_0000424" name="PP2B dissociation from camR_ca3_ACD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_64"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_14"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_64 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_221" metaid="metaid_0000425" name="PP2B dissociation from camR_ca3_BCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_65"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_15"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_65 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_222" metaid="metaid_0000426" name="PP2B dissociation from camR_ca4_ABCD" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_16"/>
        <speciesReference species="species_50"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_18 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_223" metaid="metaid_0000427" name="Ca binding to camR_CaMKII site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_35"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_224" metaid="metaid_0000428" name="Ca binding to camR_CaMKII site B " reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_36"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_225" metaid="metaid_0000429" name="Ca binding to camR_CaMKII site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_37"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_226" metaid="metaid_0000430" name="Ca binding to camR_CaMKII site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_38"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_34 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_227" metaid="metaid_0000431" name="Ca dissociation from camR_ca1_CaMKII site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_35"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_35 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_228" metaid="metaid_0000432" name="Ca dissociation from camR_ca1_CaMKII site C " reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_37"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_37 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_229" metaid="metaid_0000433" name="Ca dissociation from camR_ca1_CaMKII site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_38"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_38 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_230" metaid="metaid_0000434" name="Ca binding to camR_ca1_A_CaMKII site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_35"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_39"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_35 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_231" metaid="metaid_0000435" name="Ca binding to camR_ca1_A_CaMKII site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_35"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_40"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_35 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_232" metaid="metaid_0000436" name="Ca binding to camR_ca1_A_CaMKII site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_35"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_41"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_35 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_233" metaid="metaid_0000437" name="Ca binding to camR_ca1_B_CaMKII site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_36"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_39"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_36 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_234" metaid="metaid_0000438" name="Ca binding to camR_ca1_B_CaMKII site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_36"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_42"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_36 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_235" metaid="metaid_0000439" name="Ca binding to camR_ca1_B_CaMKII site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_36"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_43"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_36 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_236" metaid="metaid_0000440" name="Ca binding to camR_ca1_C_CaMKII site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_37"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_40"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_37 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_237" metaid="metaid_0000441" name="Ca binding to camR_ca1_C_CaMKII site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_37"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_42"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_37 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
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          <apply>
            <times/>
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    <reaction id="reaction_273" metaid="metaid_0000477" name="Ca dissociation from camR_ca3_ACD_CaMKII site C" reversible="false" sboTerm="SBO:0000180">
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            <times/>
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            <times/>
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            <times/>
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            <times/>
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            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_65 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_342" metaid="metaid_0000546" name="Ca binding to camR_ca3_ABC_PP2B site D" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_62"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_62 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_343" metaid="metaid_0000547" name="Ca binding to camR_ca3_ABD_PP2B site C" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_63"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_63 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_344" metaid="metaid_0000548" name="Ca binding to camR_ca3_ACD_PP2B site B" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_64"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_64 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_345" metaid="metaid_0000549" name="Ca binding to camR_ca3_BCD_PP2B site A" reversible="false" sboTerm="SBO:0000177">
      <listOfReactants>
        <speciesReference species="species_65"/>
        <speciesReference species="species_1"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_66"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_0 </ci>
            <ci> species_65 </ci>
            <ci> species_1 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_346" metaid="metaid_0000550" name="Ca dissociating from camR_ca4_ABCD_PP2B site A" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_65"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_1 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_347" metaid="metaid_0000551" name="Ca dissociating from camR_ca4_ABCD_PP2B site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_64"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_348" metaid="metaid_0000552" name="Ca dissociating from camR_ca4_ABCD_PP2B site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_63"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_3 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_349" metaid="metaid_0000553" name="Ca dissociating from camR_ca4_ABCD_PP2B site D" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_66"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_62"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_4 </ci>
            <ci> species_66 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_350" metaid="metaid_0000554" name="Ca dissociation from camR_ca1_CaMKII site B" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_36"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_34"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_2 </ci>
            <ci> species_36 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
    <reaction id="reaction_351" metaid="metaid_0000555" name="Ca dissociating from camT_ca3_ABC site C" reversible="false" sboTerm="SBO:0000180">
      <listOfReactants>
        <speciesReference species="species_28"/>
      </listOfReactants>
      <listOfProducts>
        <speciesReference species="species_22"/>
        <speciesReference species="species_1"/>
      </listOfProducts>
      <kineticLaw>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
          <apply>
            <times/>
            <ci> compartment_0 </ci>
            <ci> parameter_7 </ci>
            <ci> species_28 </ci>
          </apply>
        </math>
      </kineticLaw>
    </reaction>
  </listOfReactions>
</model>
</sbml>

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