Olfactory bulb microcircuits model with dual-layer inhibition (Gilra & Bhalla 2015)

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Accession:153574
A detailed network model of the dual-layer dendro-dendritic inhibitory microcircuits in the rat olfactory bulb comprising compartmental mitral, granule and PG cells developed by Aditya Gilra, Upinder S. Bhalla (2015). All cell morphologies and network connections are in NeuroML v1.8.0. PG and granule cell channels and synapses are also in NeuroML v1.8.0. Mitral cell channels and synapses are in native python.
Reference:
1 . Gilra A, Bhalla US (2015) Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding. PLoS One 10:e0098045 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Olfactory bulb;
Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell;
Channel(s): I A; I h; I K,Ca; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s): AMPA; NMDA; Gaba;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: Python; MOOSE/PyMOOSE;
Model Concept(s): Sensory processing; Sensory coding; Markov-type model; Olfaction;
Implementer(s): Bhalla, Upinder S [bhalla at ncbs.res.in]; Gilra, Aditya [aditya_gilra -at- yahoo -period- com];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron periglomerular GABA cell; Olfactory bulb main interneuron granule MC GABA cell; AMPA; NMDA; Gaba; I A; I h; I K,Ca; I Sodium; I Calcium; I Potassium; Gaba; Glutamate;
## This file is programmatically generated.

netseedstr = "100.0"
mitdistance = 400.0 # microns
mitdistancestr = "_mitdist400.0" # microns

NO_SINGLES = False
## spine inhibition and singles are self-inh
## toggle them on/off together
NO_SPINE_INH = NO_SINGLES
NO_JOINTS = False
NO_MULTIS = NO_JOINTS
NO_PGS = False

## When testing ADI (ASYM_TEST = False), fixed current in mitB to generate 80Hz. 1mM Mg++.
## When testing asymmetry in inhibition (ASYM_TEST=True), same currents in mitA and mitB, and 0.2mM Mg++.
ASYM_TEST = False
## reverse roles of mitA and mitB in activity dependent inhibition
REVERSED_ADI = True
IN_VIVO = True
## tuftinput: if ODORINH, use higher inputs to ORNs, higher gran bgnd not used.
ODORINH = True
oninject_ext = 15.0 # Hz 

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