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Mitral cell activity gating by respiration and inhibition in an olfactory bulb NN (Short et al 2016)
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To explore interactions between respiration, inhibition, and olfaction, experiments using light to active channel rhodopsin in sensory neurons expressing Olfactory Marker Protein were performed in mice and modeled in silico. This archive contains NEURON models that were run on parallel computers to explore the interactions between varying strengths of respiratory activity and olfactory sensory neuron input and the roles of periglomerular, granule, and external tufted cells in shaping mitral cell responses.
Short SM, Morse TM, McTavish TS, Shepherd GM, Verhagen JV (2016) Respiration Gates Sensory Input Responses in the Mitral Cell Layer of the Olfactory Bulb.
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Neuron or other electrically excitable cell;
Olfactory bulb main mitral GLU cell;
Olfactory bulb main interneuron periglomerular GABA cell;
Olfactory bulb main interneuron granule MC GABA cell;
Olfactory bulb main tufted cell external;
Morse, Tom [Tom.Morse at Yale.edu];
for information about:
Olfactory bulb main mitral GLU cell
Olfactory bulb main interneuron periglomerular GABA cell
Olfactory bulb main interneuron granule MC GABA cell
Files displayed below are from the
model analysis matlab code
matlab code created test data sets for experiment analysis code testing
event generator for table of prob to spikes supporting S2 fig
gui trace creation supporting information figure S3 B, C, D
matlab archive and diagnostic related
manual simulated breath writer
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