Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
ModelDB is moving. Check out our new site at
The corresponding page is
AOB mitral cell: persistent activity without feedback (Zylbertal et al., 2015)
Download zip file
Help downloading and running models
Persistent activity has been reported in many brain areas and is hypothesized to mediate working memory and emotional brain states and to rely upon network or biophysical feedback. Here we demonstrate a novel mechanism by which persistent neuronal activity can be generated without feedback, relying instead on the slow removal of Na+ from neurons following bursts of activity. This is a realistic conductance-based model that was constructed using the detailed morphology of a single typical accessory olfactory bulb (AOB) mitral cell for which the electrophysiological properties were characterized.
Zylbertal A, Kahan A, Ben-Shaul Y, Yarom Y, Wagner S (2015) Prolonged Intracellular Na+ Dynamics Govern Electrical Activity in Accessory Olfactory Bulb Mitral Cells.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Olfactory bulb (accessory) mitral cell;
I Na, leak;
Zylbertal, Asaph [asaph.zylbertal at mail.huji.ac.il];
for information about:
I Na, leak
File not selected
<- Select file from this column.
Loading data, please wait...