Cerebellar nuclear neuron (Sudhakar et al., 2015)

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Accession:185513
"... In this modeling study, we investigate different forms of Purkinje neuron simple spike pause synchrony and its influence on candidate coding strategies in the cerebellar nuclei. That is, we investigate how different alignments of synchronous pauses in synthetic Purkinje neuron spike trains affect either time-locking or rate-changes in the downstream nuclei. We find that Purkinje neuron synchrony is mainly represented by changes in the firing rate of cerebellar nuclei neurons. ..."
Reference:
1 . Sudhakar SK, Torben-Nielsen B, De Schutter E (2015) Cerebellar Nuclear Neurons Use Time and Rate Coding to Transmit Purkinje Neuron Pauses. PLoS Comput Biol 11:e1004641 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Cerebellum;
Cell Type(s): Cerebellum deep nucleus neuron;
Channel(s): I Na,p; I T low threshold; I h; I Sodium;
Gap Junctions:
Receptor(s): NMDA; Glutamate; Gaba;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Rate-coding model neurons; Rebound firing;
Implementer(s):
Search NeuronDB for information about:  NMDA; Glutamate; Gaba; I Na,p; I T low threshold; I h; I Sodium; Gaba; Glutamate;
/
SudhakarEtAl2015
readme.html
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CaL.mod
CalConc.mod *
CaLVA.mod *
DCNsyn.mod *
DCNsynGABA.mod
DCNsynNMDA.mod *
fKdr.mod *
GammaStim.mod *
h.mod *
Ifluct8.mod *
NaF.mod *
NaP.mod *
pasDCN.mod *
SK.mod *
sKdr.mod *
TNC.mod
vecevent.mod *
cellids.dat
cellids_n.dat
datasp_ex1.dat
datasp1.dat
DCN_init_model1.hoc
DCN_init_model2.hoc
DCN_init_model2_highgain.hoc
DCN_init_model2_lowgain.hoc
DCN_init_model2_medgain.hoc
DCN_init_model3.hoc
DCN_mechs1.hoc *
DCN_mechs2.hoc
DCN_morph.hoc *
DCN_params.hoc
l_ex1.dat
l1.dat
model1_params.hoc
model2_params.hoc
model2_params_highgain.hoc
model2_params_lowgain.hoc
model2_params_medgain.hoc
model3_params.hoc
mosinit.hoc
pausebeg.dat
pausebeg_n.dat
screenshot.png
                            
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255.77500000	762.90000000	1065.45000000	1577.90000000	1982.57500000	
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648.70000000	1062.67500000	1150.15000000	1677.30000000	
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195.90000000	398.72500000	534.42500000	556.52500000	573.85000000	1350.30000000	1598.55000000	1767.32500000	1827.92500000	
389.45000000	476.47500000	719.35000000	1070.45000000	1084.25000000	1167.37500000	1186.82500000	1350.55000000	1638.62500000	1931.45000000	
586.90000000	1085.72500000	1096.20000000	1865.87500000	1985.00000000	
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632.10000000	714.42500000	848.22500000	1027.55000000	1380.60000000	1523.32500000	1570.07500000	1731.12500000	1777.50000000	1882.80000000	1976.57500000	1990.47500000	
101.90000000	747.12500000	958.75000000	1135.77500000	1171.05000000	1386.47500000	1427.57500000	1427.75000000	1609.72500000	1644.60000000	1740.82500000	1807.52500000	
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136.32500000	957.67500000	1005.32500000	1042.27500000	1412.60000000	1474.10000000	1531.02500000	1629.55000000	
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57.80000000	536.12500000	660.90000000	772.75000000	993.72500000	1222.02500000	1270.57500000	1577.17500000	1749.67500000	
38.07500000	98.07500000	434.00000000	729.57500000	854.22500000	1287.37500000	1666.52500000	1743.90000000	1927.05000000	
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205.00000000	522.32500000	769.32500000	771.67500000	807.82500000	1041.72500000	1063.67500000	1556.47500000	1604.15000000	
97.42500000	285.70000000	712.37500000	873.27500000	950.67500000	1335.45000000	1475.27500000	1589.57500000	1680.25000000	1811.25000000	
275.17500000	331.32500000	350.00000000	577.17500000	659.17500000	683.00000000	748.42500000	1039.55000000	1183.07500000	1271.10000000	1391.35000000	1459.20000000	1516.67500000	1526.17500000	1572.15000000	
115.00000000	118.85000000	1187.32500000	1194.35000000	1292.05000000	1327.40000000	1374.67500000	1452.00000000	1529.32500000	1565.85000000	1918.65000000	1954.82500000	
269.55000000	329.67500000	593.10000000	1173.35000000	1278.80000000	
29.62500000	125.65000000	228.50000000	708.20000000	981.27500000	1149.45000000	1253.00000000	1355.65000000	1446.87500000	1582.12500000	1595.62500000	
266.90000000	578.15000000	1001.45000000	1257.87500000	1351.10000000	1492.12500000	1632.37500000	1651.05000000	1675.02500000	1757.97500000	1821.62500000	1853.40000000	
125.97500000	582.05000000	697.50000000	736.42500000	807.12500000	848.75000000	964.75000000	1101.25000000	1122.52500000	1263.40000000	1555.22500000	1739.30000000	1819.47500000	1870.75000000	1959.77500000	1981.07500000	
123.50000000	248.62500000	377.97500000	475.15000000	511.82500000	517.57500000	646.47500000	823.27500000	824.35000000	887.37500000	976.37500000	997.80000000	1229.07500000	1407.77500000	1765.55000000	
360.20000000	392.35000000	439.10000000	651.22500000	881.75000000	931.47500000	987.85000000	1062.47500000	1276.82500000	1360.25000000	1414.12500000	1574.50000000	1630.22500000	1811.80000000	1885.02500000	
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944.65000000	1145.55000000	1267.37500000	1269.05000000	1396.45000000	1573.02500000	1641.77500000	1686.27500000	1790.60000000	1823.02500000	
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127.82500000	278.47500000	409.15000000	787.60000000	1543.57500000	1708.75000000	1810.40000000	
539.30000000	748.17500000	980.60000000	1308.07500000	1447.82500000	1529.32500000	1837.05000000	1840.40000000	
221.60000000	254.50000000	923.07500000	1171.30000000	1185.92500000	1270.35000000	1798.12500000	1808.15000000	1866.90000000	1896.22500000	1939.47500000	1980.80000000	
159.67500000	221.52500000	228.45000000	283.92500000	556.85000000	619.82500000	746.82500000	1022.80000000	1248.15000000	1257.50000000	
47.62500000	219.70000000	942.40000000	1040.95000000	1229.55000000	1250.32500000	1400.22500000	1471.82500000	1544.55000000	1628.85000000	1689.17500000	1735.30000000	
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147.92500000	626.35000000	627.47500000	817.05000000	887.52500000	1062.72500000	1450.05000000	1564.32500000	1968.22500000	
290.55000000	467.80000000	502.92500000	1258.00000000	1293.70000000	1359.92500000	1761.75000000	1970.92500000	
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49.40000000	210.07500000	273.82500000	580.62500000	817.55000000	1374.27500000	
419.62500000	444.87500000	807.92500000	814.10000000	857.92500000	1252.17500000	1446.32500000	1754.17500000	
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82.55000000	196.67500000	202.05000000	437.27500000	903.15000000	1184.02500000	1188.95000000	1325.95000000	1370.87500000	1453.00000000	1601.15000000	1644.15000000	1913.72500000	
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31.17500000	469.47500000	490.02500000	800.25000000	979.05000000	1109.62500000	1761.50000000	1798.05000000	1871.85000000	
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308.32500000	393.80000000	400.90000000	906.00000000	1493.92500000	1551.90000000	1610.97500000	1621.20000000	1727.45000000	1902.50000000	1985.07500000	
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86.82500000	337.95000000	486.82500000	
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449.25000000	525.97500000	568.32500000	664.12500000	688.07500000	1181.45000000	1305.72500000	1786.15000000	1817.82500000	1867.90000000	
310.62500000	716.67500000	721.15000000	992.70000000	1407.30000000	1614.47500000	
151.35000000	1241.35000000	1394.85000000	1502.07500000	1573.02500000	1669.45000000	1822.65000000	1823.40000000	1836.72500000	
96.72500000	225.60000000	278.85000000	586.70000000	738.32500000	904.27500000	1109.20000000	1312.80000000	1792.80000000	1874.95000000	1941.20000000	
43.20000000	728.65000000	1417.50000000	
108.27500000	297.57500000	317.07500000	342.30000000	342.37500000	694.37500000	758.37500000	783.22500000	915.87500000	1035.97500000	1270.87500000	1405.65000000	1632.02500000	
35.85000000	304.67500000	818.47500000	969.12500000	1024.22500000	1227.77500000	1441.20000000	
202.42500000	234.02500000	449.90000000	489.05000000	525.22500000	996.17500000	1116.15000000	1242.62500000	1455.00000000	
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175.25000000	435.10000000	448.42500000	671.90000000	829.75000000	895.32500000	1590.22500000	1717.50000000	1729.00000000	1781.75000000	
466.90000000	695.90000000	761.95000000	1237.87500000	1632.57500000	1710.70000000	1725.32500000	1747.97500000	1767.62500000	1844.25000000	1932.20000000	1981.87500000	
182.87500000	199.52500000	271.15000000	757.85000000	833.92500000	1046.17500000	1904.37500000	1933.15000000	1935.90000000	
273.77500000	514.65000000	561.82500000	563.05000000	1146.20000000	1172.17500000	1183.05000000	1328.75000000	1756.05000000	
65.07500000	388.57500000	562.90000000	589.05000000	1085.37500000	1195.40000000	1566.57500000	1814.27500000	1870.27500000	1965.17500000	
37.95000000	187.27500000	703.47500000	1096.37500000	1258.25000000	1351.52500000	1600.60000000	
636.80000000	887.27500000	1189.20000000	1266.57500000	1290.17500000	1431.42500000	1507.37500000	1964.95000000	
98.35000000	863.52500000	1203.62500000	1294.40000000	1388.30000000	1599.15000000	1874.27500000	
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71.25000000	77.97500000	671.92500000	1338.50000000	1469.00000000	1771.32500000	
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93.75000000	384.95000000	448.30000000	1183.57500000	1287.82500000	1295.17500000	1333.45000000	1465.12500000	
292.55000000	364.60000000	380.30000000	956.15000000	1001.60000000	1020.12500000	1022.95000000	1254.55000000	1380.05000000	1424.35000000	1606.70000000	1714.77500000	
202.27500000	205.45000000	783.17500000	969.45000000	1521.60000000	1624.70000000	
111.65000000	209.65000000	295.85000000	466.27500000	483.20000000	743.05000000	745.97500000	1261.45000000	1267.17500000	1547.42500000	
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