Synaptic integration in a model of granule cells (Gabbiani et al 1994)

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Accession:19591
We have developed a compartmental model of a turtle cerebellar granule cell consisting of 13 compartments that represent the soma and 4 dendrites. We used this model to investigate the synaptic integration of mossy fiber inputs in granule cells. See reference or abstract at PubMed link below for more information.
Reference:
1 . Gabbiani F, Midtgaard J, Knöpfel T (1994) Synaptic integration in a model of cerebellar granule cells. J Neurophysiol 72:999-1009 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Cerebellum interneuron granule GLU cell;
Channel(s): I Na,t; I L high threshold; I K; I h; I K,Ca;
Gap Junctions:
Receptor(s): GabaA; AMPA; NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Coincidence Detection; Detailed Neuronal Models; Action Potentials; Calcium dynamics;
Implementer(s): Gabbiani, F;
Search NeuronDB for information about:  Cerebellum interneuron granule GLU cell; GabaA; AMPA; NMDA; I Na,t; I L high threshold; I K; I h; I K,Ca;
/*  %W%                    %G%            */
/* New model with the Ic current of Hines */
// xopen("stdrun2.hoc") // obsoleted by nrngui.hoc nrn v5

objref outerbox2, innerbox1, innerbox2
outerbox2 = new HBox()
outerbox2.intercept(1)

    innerbox1 = new VBox()

    innerbox1.intercept(1)

        load_file("nrngui.hoc")

        tstop = 100

        xopen("granule2.proto")


        objectvar stim
        soma stim = new IClamp(.5)
        stim.del = 5
        stim.dur = 10
        stim.amp=0.05
        // nrnmainmenu() // duplicates nrngui.hoc
        /* below can be uncommented if desired for
        // additional shape plot
        objectvar s
        s = new PlotShape()
        flush_list.append(s)
        s.save_name("flush_list.")
        */
        xpanel("clue")
        xlabel("click on below segment names to adjust max conductances")
        xpanel()
        load_template("MenuExplore")

        load_template("PointProcessLocator")

        objectvar menu_explore
        menu_explore = new MenuExplore()

    innerbox1.intercept(0)
    innerbox1.map()
    innerbox2 = new HBox()
    innerbox2.intercept(1)

        objectvar pplocator
        pplocator = new PointProcessLocator(stim)

        init()
    innerbox2.intercept(0)
    innerbox2.map()
outerbox2.intercept(0)
outerbox2.map("parameter adjustments",200,100,-1,-1)

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