Synaptic integration in a model of granule cells (Gabbiani et al 1994)

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Accession:19591
We have developed a compartmental model of a turtle cerebellar granule cell consisting of 13 compartments that represent the soma and 4 dendrites. We used this model to investigate the synaptic integration of mossy fiber inputs in granule cells. See reference or abstract at PubMed link below for more information.
Reference:
1 . Gabbiani F, Midtgaard J, Knöpfel T (1994) Synaptic integration in a model of cerebellar granule cells. J Neurophysiol 72:999-1009 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Cerebellum interneuron granule cell;
Channel(s): I Na,t; I L high threshold; I K; I h; I K,Ca;
Gap Junctions:
Receptor(s): GabaA; AMPA; NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Coincidence Detection; Detailed Neuronal Models; Action Potentials; Calcium dynamics;
Implementer(s): Gabbiani, F;
Search NeuronDB for information about:  Cerebellum interneuron granule cell; GabaA; AMPA; NMDA; I Na,t; I L high threshold; I K; I h; I K,Ca;
/*  %W%                    %G%            */
/* Prototype for different batch jobs */

xopen("granule.nrn")
access soma

insert naf_chan
	gbar_naf_chan = 0.07
insert kdr_chan
insert ka_chan
	gbar_ka_chan = 0.00367
	tauh_min_ka_chan = 12
insert h_chan
	gbar_h_chan = 9e-5
	am_h_chan = 0.0008
insert cahva_chan
insert nacaexch
insert cagrcdifus
	CaRest_cagrcdifus = 7.55e-5
insert Ic
	gbar_Ic = 0.08
insert caleak
	gbar_caleak = 4e-6
insert naleak
	gbar_naleak = 7.6e-6

for i = 0,3 {
  dendrite[i] {
    insert pas g_pas=.000033 e_pas=-65
  }
  bulb[i] {
    insert pas g_pas=.000033 e_pas=-65
  }
}

soma.eca = 80
soma.cao = 2
soma.cai = 75.5e-6

k1buf_cagrcdifus = 30
k2buf_cagrcdifus = 0.03
Buffer0_cagrcdifus = 0.025 




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