Synaptic integration in a model of granule cells (Gabbiani et al 1994)

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Accession:19591
We have developed a compartmental model of a turtle cerebellar granule cell consisting of 13 compartments that represent the soma and 4 dendrites. We used this model to investigate the synaptic integration of mossy fiber inputs in granule cells. See reference or abstract at PubMed link below for more information.
Reference:
1 . Gabbiani F, Midtgaard J, Knöpfel T (1994) Synaptic integration in a model of cerebellar granule cells. J Neurophysiol 72:999-1009 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Cerebellum interneuron granule GLU cell;
Channel(s): I Na,t; I L high threshold; I K; I h; I K,Ca;
Gap Junctions:
Receptor(s): GabaA; AMPA; NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Coincidence Detection; Detailed Neuronal Models; Action Potentials; Calcium dynamics;
Implementer(s): Gabbiani, F;
Search NeuronDB for information about:  Cerebellum interneuron granule GLU cell; GabaA; AMPA; NMDA; I Na,t; I L high threshold; I K; I h; I K,Ca;
load_file("nrngui.hoc")

objectvar scene_vector_[5]
objref outerbox0, outerbox1
objref fig2box, fig2left, fig2right
outerbox0 = new HBox()
  outerbox0.intercept(1)

  outerbox1 = new VBox()
    outerbox1.intercept(1)
    
        xpanel("Figures for Gabbiani et al 1994")
        xbutton("Figure 1A", "restart(\"fig1a\")")
        xpanel()
        fig2box = new HBox()
        fig2box.intercept(1)
            xpanel("fig2a")
            fig2left = new VBox()
            fig2left.intercept(1)
    
                xbutton("Figure 2A1", "restart(\"fig2a1\")")
                xbutton("Figure 2A2", "restart(\"fig2a2\")")
                xbutton("Figure 2A3", "restart(\"fig2a3\")")
            
            fig2left.intercept(0)
            fig2left.map()
            xpanel()
            xpanel("fig2b")
            fig2right = new VBox()
            fig2right.intercept(1)
    
                xbutton("Figure 2B1", "restart(\"fig2b1\")")
                xbutton("Figure 2B2", "restart(\"fig2b2\")")
                xbutton("Figure 2B3", "restart(\"fig2b3\")")
    
            fig2right.intercept(0)
            fig2right.map()
        
            xpanel(5,100)
        fig2box.intercept(0)
        fig2box.map()
    outerbox1.intercept(0)
    outerbox1.map("simulation control",50,50,-1,-1)

    load_file("runctrl.ses")


outerbox0.intercept(0)
outerbox0.map("simulation control",50,50,-1,-1)

load_file("granule2.oc")

strdef tstr

pwmcnt = PWManager[0].count // the initial gui should not be dismissed

proc restart() {local i
	print PWManager[0].count
	print " as compared to ",pwmcnt
	objref graphItem, save_window_
	for i=0, n_graph_lists-1 {
			graphList[i].remove_all()
		}
		flush_list.remove_all()
		fast_flush_list.remove_all()
		doNotify()

	for (i= PWManager[0].count-1; i >= pwmcnt; i -= 1) {
		PWManager[0].close(i)
		doNotify()
	}
	stoprun = 0
	cvode_active(0)

	dt = .025
	steps_per_ms = 40

	sprint(tstr, "%s.hoc", $s1)
	load_file(1, tstr)
}

// use show diameter version
Shape[0].exec_menu("Show Diam")
Shape[1].exec_menu("Show Diam")


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