Olfactory Mitral cell: AP initiation modes (Chen et al 2002)

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Accession:3793
The mitral cell primary dendrite plays an important role in transmitting distal olfactory nerve input from olfactory glomerulus to the soma-axon initial segment. To understand how dendritic active properties are involved in this transmission, we have combined dual soma and dendritic patch recordings with computational modeling to analyze action-potential initiation and propagation in the primary dendrite.
Reference:
1 . Chen WR, Shen GY, Shepherd GM, Hines ML, Midtgaard J (2002) Multiple modes of action potential initiation and propagation in mitral cell primary dendrite. J Neurophysiol 88:2755-64 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Olfactory bulb main mitral GLU cell; Myelinated neuron;
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s): AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Synaptic Integration; Olfaction;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; AMPA; I Na,t; I K;
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320
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9.4
9.45
9.5
9.55
9.6
9.65
9.7
9.75
9.8
9.85
9.9
9.95
10
10.1
10.1
10.2
10.2
10.3
10.3
10.4
10.4
10.5
10.5
10.6
10.6
10.7
10.7
10.8
10.8
10.9
10.9
11
11
11.1
11.1
11.2
11.2
11.3
11.3
11.4
11.4
11.5
11.5
11.6
11.6
11.7
11.7
11.8
11.8
11.9
11.9
12
12
12.1
12.1
12.2
12.2
12.3
12.3
12.4
12.4
12.5
12.5
12.6
12.6
12.7
12.7
12.8
12.8
12.9
12.9
13
13
13.1
13.1
13.2
13.2
13.3
13.3
13.4
13.4
13.5
13.5
13.6
13.6
13.7
13.7
13.8
13.8
13.9
13.9
14
14
14.1
14.1
14.2
14.2
14.3
14.3
14.4
14.4
14.5
14.5
14.6
14.6
14.7
14.7
14.8
14.8
14.9
14.9
15
15
15.1
15.1
15.2
15.2
15.3
15.3
15.4
15.4
15.5
15.5
15.6
15.6
15.7
15.7
15.8
15.8
15.9
15.9
16

-64.2
-64.5
-64.1
-64.3
-64.4
-64.3
-64.2
-64.2
-64.5
-64.2
-64.1
-64.2
-64.2
-64.1
-64.3
-64.1
-64.3
-64.2
-64.2
-64.2
-64.1
-63.9
-64.5
-64.2
-64.2
-63.9
-64
-63.8
-63.9
-63.8
-63.7
-63.7
-63.6
-63.5
-63.3
-63.4
-63.1
-63
-63.2
-62.9
-62.9
-62.5
-62.7
-62.5
-62.4
-62.2
-62.5
-62.2
-62.2
-62
-61.8
-61.8
-61.8
-61.7
-61.6
-61.6
-61.5
-61.4
-61.3
-60.9
-61.2
-61
-60.9
-60.6
-60.9
-60.7
-60.5
-60.6
-60.4
-60.3
-60.4
-60.2
-59.8
-59.9
-59.8
-59.7
-59.7
-59.6
-59.4
-59.5
-59.2
-59.1
-59.1
-58.9
-58.8
-58.8
-58.5
-58.5
-58.3
-58.2
-58.2
-58
-58.2
-57.9
-57.6
-57.8
-57.5
-57.5
-57.2
-57
-57.1
-56.8
-56.9
-56.8
-56.7
-56.5
-56.3
-56.1
-55.9
-55.7
-55.6
-55.7
-55.2
-55.3
-55.1
-54.9
-54.7
-54.4
-54.1
-53.8
-53.8
-53.8
-53.2
-53.1
-52.7
-52.5
-52.2
-51.8
-51.4
-51.2
-50.8
-50.1
-49.6
-48.8
-47.9
-46.7
-45.2
-42.9
-39.3
-32.9
-19.219
-1
12.7
19.7
22.4
22.9
20.7
17.4
12.7
7.1
1.5
-3.6
-8.1
-12.83
-16.76
-20.91
-24.49
-28.38
-32.4
-35.9
-39.7
-43.1
-46.6
-49.9
-52.8
-55.4
-57.3
-59.4
-61
-62
-63.2
-64
-65
-65.7
-66.2
-66.6
-67.1
-67.2
-67.3
-67.5
-67.6
-68.1
-67.9
-68
-68.1
-68
-67.9
-67.8
-67.9
-67.9
-67.6
-67.8
-67.5
-67.6
-67.5
-67.5
-67.3
-67.3
-67.2
-67.2
-67.2
-67.1
-66.9
-67
-66.7
-66.9
-66.5
-66.8
-66.5
-66.4
-66.6
-66.3
-66.3
-66.2
-66.2
-66
-66
-66.1
-65.8
-66
-65.5
-66
-65.6
-65.6
-65.5
-65.6
-65.4
-65.6
-65.8
-65.7
-65.9
-65.6
-65.8
-65.8
-65.8
-66
-65.8
-65.9
-66.2
-66
-66.1
-66
-66
-65.9
-65.9
-66
-66.2
-65.9
-66.3
-66.1
-66.1
-66.4
-66.4
-66
-66.1
-66.1
-66.2
-66.2
-66.2
-66.5
-66.2
-66.3
-66.3
-66.2
-66.4
-66.5
-66.3
-66.4
-66.3
-66.4
-66.6
-66.5
-66.5
-66.6
-66.3
-66.5
-66.3
-66.5
-66.8
-66.4
-66.6
-66.5
-66.6
-66.3
-66.8
-66.6
-66.5
-66.5
-66.6
-66.4
-66.8
-66.8
-66.6
-66.6
-66.9
-66.4
-66.8
-66.7
-66.6
-66.7
-66.6
-66.5
-66.8
-66.6
-66.5
-66.7
-66.6
-66.4
-66.6
-66.7
-66.9
-66.8
-66.5
-66.7
-66.4
-66.7
-66.6
-66.5
-66.8
-66.7

2
0.225
15.75

0
1

RegionFitness xdat ydat boundary weight (lines=648) 1
||
320
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0.45
0.5
0.55
0.6
0.65
0.7
0.75
0.8
0.85
0.9
0.95
1
1.05
1.1
1.15
1.2
1.25
1.3
1.35
1.4
1.45
1.5
1.55
1.6
1.65
1.7
1.75
1.8
1.85
1.9
1.95
2
2.05
2.1
2.15
2.2
2.25
2.3
2.35
2.4
2.45
2.5
2.55
2.6
2.65
2.7
2.75
2.8
2.85
2.9
2.95
3
3.05
3.1
3.15
3.2
3.25
3.3
3.35
3.4
3.45
3.5
3.55
3.6
3.65
3.7
3.75
3.8
3.85
3.9
3.95
4
4.05
4.1
4.15
4.2
4.25
4.3
4.35
4.4
4.45
4.5
4.55
4.6
4.65
4.7
4.75
4.8
4.85
4.9
4.95
5
5.05
5.1
5.15
5.2
5.25
5.3
5.35
5.4
5.45
5.5
5.55
5.6
5.65
5.7
5.75
5.8
5.85
5.9
5.95
6
6.05
6.1
6.15
6.2
6.25
6.3
6.35
6.4
6.45
6.5
6.55
6.6
6.65
6.7
6.75
6.8
6.85
6.9
6.95
7
7.05
7.1
7.15
7.2
7.25
7.3
7.35
7.4
7.45
7.5
7.55
7.6
7.65
7.7
7.75
7.8
7.85
7.9
7.95
8
8.05
8.1
8.15
8.2
8.25
8.3
8.35
8.4
8.45
8.5
8.55
8.6
8.65
8.7
8.75
8.8
8.85
8.9
8.95
9
9.05
9.1
9.15
9.2
9.25
9.3
9.35
9.4
9.45
9.5
9.55
9.6
9.65
9.7
9.75
9.8
9.85
9.9
9.95
10
10.1
10.1
10.2
10.2
10.3
10.3
10.4
10.4
10.5
10.5
10.6
10.6
10.7
10.7
10.8
10.8
10.9
10.9
11
11
11.1
11.1
11.2
11.2
11.3
11.3
11.4
11.4
11.5
11.5
11.6
11.6
11.7
11.7
11.8
11.8
11.9
11.9
12
12
12.1
12.1
12.2
12.2
12.3
12.3
12.4
12.4
12.5
12.5
12.6
12.6
12.7
12.7
12.8
12.8
12.9
12.9
13
13
13.1
13.1
13.2
13.2
13.3
13.3
13.4
13.4
13.5
13.5
13.6
13.6
13.7
13.7
13.8
13.8
13.9
13.9
14
14
14.1
14.1
14.2
14.2
14.3
14.3
14.4
14.4
14.5
14.5
14.6
14.6
14.7
14.7
14.8
14.8
14.9
14.9
15
15
15.1
15.1
15.2
15.2
15.3
15.3
15.4
15.4
15.5
15.5
15.6
15.6
15.7
15.7
15.8
15.8
15.9
15.9
16

-54.5
-54.5
-54.5
-54.5
-54.6
-54.5
-54.4
-54.4
-54.4
-54.7
-54.5
-54.4
-54.5
-54.5
-54.4
-54.5
-54.6
-54.7
-54.8
-54.6
-54.6
-61.1
-60.4
-56.8
-55
-54.3
-53.7
-53.1
-52.6
-52.1
-51.9
-51.5
-51.2
-51
-50.9
-50.7
-50.3
-50.1
-49.7
-49.6
-49.4
-49.3
-49.2
-49
-48.8
-48.7
-48.6
-48.4
-48.2
-48
-48
-47.8
-47.7
-47.5
-47.5
-47.2
-46.9
-46.8
-46.9
-46.6
-46.5
-46.5
-46.1
-46.1
-46
-45.8
-45.7
-45.5
-45.4
-45.4
-45.1
-45
-44.9
-44.8
-44.7
-44.5
-44.5
-44.4
-43.9
-44
-43.9
-43.8
-43.7
-43.3
-43.3
-43.2
-43.1
-42.8
-42.7
-42.7
-42.5
-42.5
-42.3
-42.2
-42.1
-42
-41.7
-41.7
-41.5
-41.3
-41.3
-41.1
-40.9
-40.7
-40.7
-40.5
-40.3
-40.2
-40
-39.9
-39.6
-39.5
-39.3
-39.2
-38.9
-38.8
-38.6
-38.5
-38.3
-38.1
-38
-37.8
-37.7
-37.4
-37.2
-36.7
-36.4
-36.1
-35.9
-35.5
-35.2
-34.9
-34.4
-34
-33.3
-32.7
-32.3
-31.5
-30.4
-29.1
-27.4
-24.9
-20.7
-14.04
-4.18
5.7
13
17.5
19.6
19.4
17.7
14.8
11
6.9
2.3
-2.41
-6.55
-11.06
-15.43
-19.6
-23.6
-27.5
-31.1
-34.4
-37.5
-40.2
-42.7
-44.9
-46.8
-48.5
-49.8
-51.1
-52
-53
-53.7
-54.2
-54.7
-55.1
-55.3
-55.6
-55.5
-55.8
-55.9
-55.7
-55.8
-55.5
-55.5
-55.4
-55.4
-55.2
-55.2
-54.8
-54.8
-54.8
-54.5
-54.5
-54.4
-54.1
-54
-53.7
-53.5
-53.4
-53.3
-53.1
-52.9
-52.8
-52.7
-52.6
-52.5
-52.3
-52.2
-52.1
-51.9
-51.8
-51.6
-51.5
-51.5
-51.3
-51.1
-50.8
-50.9
-45.7
-44
-47.9
-49.5
-50.4
-51.1
-51.4
-51.8
-52.1
-52.4
-52.5
-52.7
-52.9
-53.1
-53.3
-53.2
-53.3
-53.6
-53.6
-53.6
-53.8
-53.8
-54
-54.1
-54.2
-54.2
-54.2
-54.2
-54.4
-54.5
-54.7
-54.6
-54.8
-54.7
-54.8
-54.7
-55
-55
-55
-54.9
-54.8
-55.1
-55.3
-55.3
-55.4
-55.4
-55.4
-55.5
-55.5
-55.6
-55.6
-55.6
-55.6
-55.5
-55.4
-55.5
-55.6
-55.7
-55.7
-55.7
-55.7
-55.8
-55.8
-55.8
-55.8
-55.9
-55.9
-55.9
-55.7
-55.8
-55.9
-55.9
-55.9
-56
-56.1
-56.1
-56
-55.9
-56
-56.2
-56.1
-56.2
-56.2
-56.3
-56.2
-56.2
-56.2
-56.2
-56.2
-56.2
-56.2
-56.3
-56.3
-56.2
-56.2
-56.3
-56.3
-56.3
-56.4

2
1.075
10.75

0
1

1
RegionFitness xdat ydat boundary weight (lines=648) 1
||
320
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0.45
0.5
0.55
0.6
0.65
0.7
0.75
0.8
0.85
0.9
0.95
1
1.05
1.1
1.15
1.2
1.25
1.3
1.35
1.4
1.45
1.5
1.55
1.6
1.65
1.7
1.75
1.8
1.85
1.9
1.95
2
2.05
2.1
2.15
2.2
2.25
2.3
2.35
2.4
2.45
2.5
2.55
2.6
2.65
2.7
2.75
2.8
2.85
2.9
2.95
3
3.05
3.1
3.15
3.2
3.25
3.3
3.35
3.4
3.45
3.5
3.55
3.6
3.65
3.7
3.75
3.8
3.85
3.9
3.95
4
4.05
4.1
4.15
4.2
4.25
4.3
4.35
4.4
4.45
4.5
4.55
4.6
4.65
4.7
4.75
4.8
4.85
4.9
4.95
5
5.05
5.1
5.15
5.2
5.25
5.3
5.35
5.4
5.45
5.5
5.55
5.6
5.65
5.7
5.75
5.8
5.85
5.9
5.95
6
6.05
6.1
6.15
6.2
6.25
6.3
6.35
6.4
6.45
6.5
6.55
6.6
6.65
6.7
6.75
6.8
6.85
6.9
6.95
7
7.05
7.1
7.15
7.2
7.25
7.3
7.35
7.4
7.45
7.5
7.55
7.6
7.65
7.7
7.75
7.8
7.85
7.9
7.95
8
8.05
8.1
8.15
8.2
8.25
8.3
8.35
8.4
8.45
8.5
8.55
8.6
8.65
8.7
8.75
8.8
8.85
8.9
8.95
9
9.05
9.1
9.15
9.2
9.25
9.3
9.35
9.4
9.45
9.5
9.55
9.6
9.65
9.7
9.75
9.8
9.85
9.9
9.95
10
10.1
10.1
10.2
10.2
10.3
10.3
10.4
10.4
10.5
10.5
10.6
10.6
10.7
10.7
10.8
10.8
10.9
10.9
11
11
11.1
11.1
11.2
11.2
11.3
11.3
11.4
11.4
11.5
11.5
11.6
11.6
11.7
11.7
11.8
11.8
11.9
11.9
12
12
12.1
12.1
12.2
12.2
12.3
12.3
12.4
12.4
12.5
12.5
12.6
12.6
12.7
12.7
12.8
12.8
12.9
12.9
13
13
13.1
13.1
13.2
13.2
13.3
13.3
13.4
13.4
13.5
13.5
13.6
13.6
13.7
13.7
13.8
13.8
13.9
13.9
14
14
14.1
14.1
14.2
14.2
14.3
14.3
14.4
14.4
14.5
14.5
14.6
14.6
14.7
14.7
14.8
14.8
14.9
14.9
15
15
15.1
15.1
15.2
15.2
15.3
15.3
15.4
15.4
15.5
15.5
15.6
15.6
15.7
15.7
15.8
15.8
15.9
15.9
16

-63
-63
-63.1
-63.3
-63.2
-62.9
-63.1
-62.9
-63.4
-63.1
-63
-63
-62.9
-63.1
-63
-62.9
-62.9
-63.4
-63.2
-63
-62.8
-65
-63.7
-63.2
-62.7
-62.3
-61.7
-61.7
-61.3
-60.9
-60.6
-60.4
-60.3
-59.6
-59.4
-59.4
-59
-58.7
-58.4
-58
-58
-57.7
-57.4
-57.2
-57
-56.8
-56.7
-56.4
-56
-55.9
-55.6
-55.5
-55
-54.9
-54.5
-54.5
-54.3
-53.6
-53.4
-53.2
-52.9
-52.5
-52.3
-51.8
-51.6
-51.2
-50.5
-50
-49.3
-48.8
-47.9
-46.8
-45.5
-43.6
-40.3
-34.4
-21.38
-2.9
11.6
19.3
23
23.5
22.3
19.5
15.5
11.2
5.9
0.8
-4.2
-8.47
-12.59
-16.57
-20.62
-24.05
-27.67
-31.2
-34.8
-38.4
-42
-44.7
-47.9
-50.5
-53
-55
-56.5
-58.1
-59.3
-60.6
-61.2
-61.8
-62.4
-63
-63.2
-63.4
-63.6
-63.9
-64
-63.8
-63.8
-63.8
-63.9
-64.1
-63.6
-63.5
-63.5
-63.3
-63.5
-63.2
-62.8
-62.9
-63
-62.7
-62.6
-62.7
-62.3
-62.2
-61.8
-61.8
-61.6
-61.7
-61.6
-61.1
-61.3
-61.2
-61
-61
-60.6
-60.6
-60.5
-60.4
-60.2
-60.2
-60
-60
-60
-59.5
-59.5
-59.6
-59.5
-59.6
-58.9
-59.1
-59
-59
-58.7
-58.6
-58.6
-58.4
-58.5
-58.1
-57.9
-57.9
-58
-57.6
-57.4
-57.4
-57.2
-57.4
-57.1
-57.2
-57.1
-57
-56.8
-56.5
-56.2
-56.5
-56.4
-56.1
-55.8
-55.9
-55.8
-55.8
-55.5
-55.3
-55.3
-55.3
-55.3
-55.1
-54.8
-54.9
-54.6
-54.8
-54.3
-54.2
-54.2
-54
-53.8
-53.7
-53.6
-53.6
-53.4
-52.9
-53
-52.9
-52.6
-52.7
-52.2
-52.1
-52.2
-51.7
-51.6
-48.6
-50.5
-51.1
-51.5
-51.5
-51.8
-52.2
-52.4
-52.6
-52.5
-52.7
-53.1
-53.2
-53.2
-53.2
-53.5
-53.6
-53.8
-54
-53.9
-54.2
-54.5
-54.5
-54.3
-54.5
-54.5
-54.8
-54.9
-54.9
-55.1
-55
-55.3
-55.2
-55.3
-55.5
-55.7
-55.7
-55.5
-55.9
-55.9
-56.2
-56
-56
-56.2
-56.2
-56.5
-56.3
-56.2
-56.4
-56.6
-56.6
-56.5
-56.5
-56.7
-56.7
-56.7
-56.5
-56.8
-56.8
-57
-56.9
-56.8
-57.1
-57.3
-57.2
-57.2
-57.1
-57.2
-57.3
-57.5
-57
-57.3
-57.6
-57.6
-57.3
-57.3
-57.4
-57.7
-57.6
-57.6
-57.7
-57.7
-57.7
-58
-57.8
-57.9
-57.9
-58.2
-58
-57.7
-57.8
-58
-58.4
-58
-58.1
-58.1
-58.1
-58.3
-58.1

2
1.025
10.95

0
1

RegionFitness xdat ydat boundary weight (lines=648) 1
||
320
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0.45
0.5
0.55
0.6
0.65
0.7
0.75
0.8
0.85
0.9
0.95
1
1.05
1.1
1.15
1.2
1.25
1.3
1.35
1.4
1.45
1.5
1.55
1.6
1.65
1.7
1.75
1.8
1.85
1.9
1.95
2
2.05
2.1
2.15
2.2
2.25
2.3
2.35
2.4
2.45
2.5
2.55
2.6
2.65
2.7
2.75
2.8
2.85
2.9
2.95
3
3.05
3.1
3.15
3.2
3.25
3.3
3.35
3.4
3.45
3.5
3.55
3.6
3.65
3.7
3.75
3.8
3.85
3.9
3.95
4
4.05
4.1
4.15
4.2
4.25
4.3
4.35
4.4
4.45
4.5
4.55
4.6
4.65
4.7
4.75
4.8
4.85
4.9
4.95
5
5.05
5.1
5.15
5.2
5.25
5.3
5.35
5.4
5.45
5.5
5.55
5.6
5.65
5.7
5.75
5.8
5.85
5.9
5.95
6
6.05
6.1
6.15
6.2
6.25
6.3
6.35
6.4
6.45
6.5
6.55
6.6
6.65
6.7
6.75
6.8
6.85
6.9
6.95
7
7.05
7.1
7.15
7.2
7.25
7.3
7.35
7.4
7.45
7.5
7.55
7.6
7.65
7.7
7.75
7.8
7.85
7.9
7.95
8
8.05
8.1
8.15
8.2
8.25
8.3
8.35
8.4
8.45
8.5
8.55
8.6
8.65
8.7
8.75
8.8
8.85
8.9
8.95
9
9.05
9.1
9.15
9.2
9.25
9.3
9.35
9.4
9.45
9.5
9.55
9.6
9.65
9.7
9.75
9.8
9.85
9.9
9.95
10
10.1
10.1
10.2
10.2
10.3
10.3
10.4
10.4
10.5
10.5
10.6
10.6
10.7
10.7
10.8
10.8
10.9
10.9
11
11
11.1
11.1
11.2
11.2
11.3
11.3
11.4
11.4
11.5
11.5
11.6
11.6
11.7
11.7
11.8
11.8
11.9
11.9
12
12
12.1
12.1
12.2
12.2
12.3
12.3
12.4
12.4
12.5
12.5
12.6
12.6
12.7
12.7
12.8
12.8
12.9
12.9
13
13
13.1
13.1
13.2
13.2
13.3
13.3
13.4
13.4
13.5
13.5
13.6
13.6
13.7
13.7
13.8
13.8
13.9
13.9
14
14
14.1
14.1
14.2
14.2
14.3
14.3
14.4
14.4
14.5
14.5
14.6
14.6
14.7
14.7
14.8
14.8
14.9
14.9
15
15
15.1
15.1
15.2
15.2
15.3
15.3
15.4
15.4
15.5
15.5
15.6
15.6
15.7
15.7
15.8
15.8
15.9
15.9
16

-64.2
-64.2
-64.1
-64.1
-64.1
-64.2
-64.1
-64
-64
-64
-63.9
-64
-64
-63.8
-64
-64.1
-64.2
-63.9
-64
-64
-64.2
-64.3
-64.3
-64.2
-64
-64
-64
-63.7
-63.7
-63.4
-63.5
-63.3
-63.2
-63
-62.8
-62.7
-62.6
-62.4
-62.4
-62.2
-61.9
-61.8
-61.7
-61.6
-61.3
-61.2
-61
-60.9
-60.6
-60.6
-60.3
-60.2
-60.1
-59.9
-59.8
-59.6
-59.4
-59.3
-59.1
-58.9
-58.7
-58.4
-58.3
-58
-57.9
-57.7
-57.4
-57.2
-57
-56.5
-56.4
-55.9
-55.6
-55.1
-54.9
-54.2
-53.4
-52.5
-50.7
-47.8
-42.9
-35.7
-26.28
-15.41
-5.9
1.4
6.4
8.6
9
7.9
5.5
2.7
-0.3
-3.5
-7
-10.74
-14.41
-18.444
-22.58
-26.67
-31
-35.1
-38.5
-41.9
-45.2
-48.1
-51
-53.3
-55.6
-57.3
-58.8
-60.4
-61.6
-62.8
-63.5
-64.3
-64.8
-65.3
-65.5
-66
-66
-66.2
-66.5
-66.4
-66.4
-66.5
-66.3
-66.4
-66.2
-66.3
-66.1
-66
-66
-65.9
-65.7
-65.5
-65.3
-65.3
-65.2
-65
-64.8
-64.8
-64.6
-64.5
-64.5
-64.4
-64.2
-64.1
-64
-63.7
-63.5
-63.4
-63.4
-63.1
-63
-62.9
-63
-63.2
-62.9
-62.9
-62.5
-62.5
-62.3
-62.2
-62.2
-62.1
-61.9
-61.8
-61.7
-61.7
-61.5
-61.4
-61.2
-61.2
-61.1
-61
-60.9
-60.6
-60.5
-60.3
-60
-59.8
-59.7
-59.8
-59.7
-59.5
-59.5
-59.4
-59.4
-59.1
-59
-58.8
-58.8
-58.6
-58.5
-58.4
-58.3
-58.2
-58.2
-58
-57.9
-57.8
-57.6
-57.5
-57.4
-57.3
-57.6
-57.8
-57.4
-57
-56.7
-56.5
-56.4
-56.4
-56.3
-56.2
-56.1
-55.8
-55.8
-55.8
-55.7
-55.5
-55.2
-55.3
-55.1
-54.9
-55
-55
-54.9
-55.1
-55
-55.1
-55.1
-55.2
-55.1
-55.3
-55.3
-55.3
-55.3
-55.7
-55.5
-55.4
-55.5
-55.6
-55.8
-55.8
-55.9
-55.9
-56
-56
-56
-56.1
-56.1
-56.3
-56.2
-56.2
-56.3
-56.4
-56.3
-56.5
-56.5
-56.5
-56.7
-56.6
-56.7
-56.7
-56.7
-56.8
-56.9
-56.8
-56.9
-57
-57.2
-57
-57.2
-57.1
-57.4
-57.3
-57.4
-57.2
-57.4
-57.5
-57.4
-57.6
-57.5
-57.5
-57.6
-57.8
-57.8
-57.9
-57.8
-57.8
-57.9
-58
-57.9
-58.1
-58.2
-58.2
-58
-58.2
-58.2
-58.3
-58.4
-58.4
-58.5
-58.5
-58.6
-58.4
-58.5
-58.6
-58.7
-58.6
-58.7
-58.8
-58.6
-58.8
-58.6
-58.8
-58.9
-58.9

2
0
16

0
1

1
RegionFitness xdat ydat boundary weight (lines=648) 1
||
320
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0.45
0.5
0.55
0.6
0.65
0.7
0.75
0.8
0.85
0.9
0.95
1
1.05
1.1
1.15
1.2
1.25
1.3
1.35
1.4
1.45
1.5
1.55
1.6
1.65
1.7
1.75
1.8
1.85
1.9
1.95
2
2.05
2.1
2.15
2.2
2.25
2.3
2.35
2.4
2.45
2.5
2.55
2.6
2.65
2.7
2.75
2.8
2.85
2.9
2.95
3
3.05
3.1
3.15
3.2
3.25
3.3
3.35
3.4
3.45
3.5
3.55
3.6
3.65
3.7
3.75
3.8
3.85
3.9
3.95
4
4.05
4.1
4.15
4.2
4.25
4.3
4.35
4.4
4.45
4.5
4.55
4.6
4.65
4.7
4.75
4.8
4.85
4.9
4.95
5
5.05
5.1
5.15
5.2
5.25
5.3
5.35
5.4
5.45
5.5
5.55
5.6
5.65
5.7
5.75
5.8
5.85
5.9
5.95
6
6.05
6.1
6.15
6.2
6.25
6.3
6.35
6.4
6.45
6.5
6.55
6.6
6.65
6.7
6.75
6.8
6.85
6.9
6.95
7
7.05
7.1
7.15
7.2
7.25
7.3
7.35
7.4
7.45
7.5
7.55
7.6
7.65
7.7
7.75
7.8
7.85
7.9
7.95
8
8.05
8.1
8.15
8.2
8.25
8.3
8.35
8.4
8.45
8.5
8.55
8.6
8.65
8.7
8.75
8.8
8.85
8.9
8.95
9
9.05
9.1
9.15
9.2
9.25
9.3
9.35
9.4
9.45
9.5
9.55
9.6
9.65
9.7
9.75
9.8
9.85
9.9
9.95
10
10.1
10.1
10.2
10.2
10.3
10.3
10.4
10.4
10.5
10.5
10.6
10.6
10.7
10.7
10.8
10.8
10.9
10.9
11
11
11.1
11.1
11.2
11.2
11.3
11.3
11.4
11.4
11.5
11.5
11.6
11.6
11.7
11.7
11.8
11.8
11.9
11.9
12
12
12.1
12.1
12.2
12.2
12.3
12.3
12.4
12.4
12.5
12.5
12.6
12.6
12.7
12.7
12.8
12.8
12.9
12.9
13
13
13.1
13.1
13.2
13.2
13.3
13.3
13.4
13.4
13.5
13.5
13.6
13.6
13.7
13.7
13.8
13.8
13.9
13.9
14
14
14.1
14.1
14.2
14.2
14.3
14.3
14.4
14.4
14.5
14.5
14.6
14.6
14.7
14.7
14.8
14.8
14.9
14.9
15
15
15.1
15.1
15.2
15.2
15.3
15.3
15.4
15.4
15.5
15.5
15.6
15.6
15.7
15.7
15.8
15.8
15.9
15.9
16

-63.8
-63.3
-63.2
-63.4
-63.5
-63.6
-63.3
-63.4
-63.3
-63.6
-63.5
-63.4
-63.4
-63.4
-63.6
-63.3
-63.4
-63.3
-63.5
-63.7
-63.3
-64.1
-63.9
-63.4
-63.3
-62.8
-62.7
-62.6
-62.5
-62.3
-62.3
-62
-62
-61.8
-61.6
-61.4
-61.4
-61.1
-61.3
-60.8
-61
-60.9
-60.5
-60.6
-60.3
-60.4
-60.6
-60.4
-60.2
-60.2
-60.1
-59.9
-59.9
-59.8
-59.4
-59.6
-59.4
-59.6
-59.2
-59.4
-59.2
-59.2
-59.1
-58.7
-58.8
-58.9
-58.5
-58.5
-58.3
-58.2
-58.2
-58
-58
-57.9
-57.8
-57.7
-57.6
-57.6
-57.4
-57.3
-57.4
-57.2
-56.8
-56.9
-56.7
-56.4
-56.6
-56.3
-56.5
-56.3
-56.3
-55.9
-55.9
-55.8
-55.8
-55.6
-55.3
-55.2
-55.2
-55.2
-54.9
-54.4
-54.9
-54.4
-54.5
-54.4
-54.1
-54.2
-53.8
-53.7
-53.4
-53.5
-53
-53.1
-52.8
-52.5
-52.4
-52.3
-52.1
-51.7
-51.3
-51.4
-50.9
-50.6
-50
-50
-49.7
-49.1
-48.6
-48.1
-47.1
-46.3
-45.4
-43.5
-41
-37.5
-29.2
-14.66
2.5
13.6
19.2
21.6
21.4
19.8
16.4
12.1
7.4
2.8
-1.8
-6.1
-10.4
-14.41
-18.081
-21.89
-25.63
-29.3
-32.9
-36.3
-39.7
-43.2
-46.3
-49.3
-51.6
-54
-56.3
-57.6
-59
-60.3
-61.4
-62.3
-62.7
-63.2
-63.8
-64.1
-64.5
-64.7
-64.9
-65.2
-65.4
-65.2
-65.2
-65.4
-65.6
-65.7
-65.6
-65.5
-65.2
-65.4
-65.3
-65.5
-65.2
-65.5
-65.2
-64.8
-64.7
-64.9
-64.7
-64.7
-64.7
-64.5
-64.5
-64.5
-64.2
-64.2
-64
-64
-64.2
-64.3
-63.7
-63.7
-63.8
-63.7
-63.6
-63.7
-63.7
-63.9
-63.6
-63.3
-63.3
-63.3
-63.3
-61.8
-62.7
-62.9
-63.3
-63.4
-63.4
-63.3
-63.6
-63.9
-63.8
-63.8
-64.1
-64.2
-64.2
-64.2
-64.1
-64.1
-64.3
-64.4
-64.2
-64.2
-64.4
-64.6
-64.5
-64.6
-64.4
-64.5
-64.7
-64.4
-64.8
-64.8
-64.3
-64.8
-64.7
-64.7
-64.8
-64.8
-64.8
-64.9
-64.9
-65
-65
-64.9
-65
-64.9
-65.1
-64.9
-65.1
-65.1
-64.8
-65.4
-65.2
-65
-64.9
-65.1
-65.1
-65.1
-65
-65
-65.2
-65.2
-65
-65.1
-65.1
-65
-65.1
-65
-65
-65.2
-65.4
-65.2
-65.2
-65.1
-65.3
-65.5
-65
-65.4
-65.2
-65.2
-65.2
-65.4
-65.4
-65.3
-65.5
-65.3
-65.3
-65.3
-65.2
-65.4
-65.4
-65.3
-65.3
-65.5
-65.5
-65.5
-65.1
-65.5
-65.6
-65.4

2
0.975
10.95

0
1

RegionFitness xdat ydat boundary weight (lines=648) 1
||
320
0
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0.45
0.5
0.55
0.6
0.65
0.7
0.75
0.8
0.85
0.9
0.95
1
1.05
1.1
1.15
1.2
1.25
1.3
1.35
1.4
1.45
1.5
1.55
1.6
1.65
1.7
1.75
1.8
1.85
1.9
1.95
2
2.05
2.1
2.15
2.2
2.25
2.3
2.35
2.4
2.45
2.5
2.55
2.6
2.65
2.7
2.75
2.8
2.85
2.9
2.95
3
3.05
3.1
3.15
3.2
3.25
3.3
3.35
3.4
3.45
3.5
3.55
3.6
3.65
3.7
3.75
3.8
3.85
3.9
3.95
4
4.05
4.1
4.15
4.2
4.25
4.3
4.35
4.4
4.45
4.5
4.55
4.6
4.65
4.7
4.75
4.8
4.85
4.9
4.95
5
5.05
5.1
5.15
5.2
5.25
5.3
5.35
5.4
5.45
5.5
5.55
5.6
5.65
5.7
5.75
5.8
5.85
5.9
5.95
6
6.05
6.1
6.15
6.2
6.25
6.3
6.35
6.4
6.45
6.5
6.55
6.6
6.65
6.7
6.75
6.8
6.85
6.9
6.95
7
7.05
7.1
7.15
7.2
7.25
7.3
7.35
7.4
7.45
7.5
7.55
7.6
7.65
7.7
7.75
7.8
7.85
7.9
7.95
8
8.05
8.1
8.15
8.2
8.25
8.3
8.35
8.4
8.45
8.5
8.55
8.6
8.65
8.7
8.75
8.8
8.85
8.9
8.95
9
9.05
9.1
9.15
9.2
9.25
9.3
9.35
9.4
9.45
9.5
9.55
9.6
9.65
9.7
9.75
9.8
9.85
9.9
9.95
10
10.1
10.1
10.2
10.2
10.3
10.3
10.4
10.4
10.5
10.5
10.6
10.6
10.7
10.7
10.8
10.8
10.9
10.9
11
11
11.1
11.1
11.2
11.2
11.3
11.3
11.4
11.4
11.5
11.5
11.6
11.6
11.7
11.7
11.8
11.8
11.9
11.9
12
12
12.1
12.1
12.2
12.2
12.3
12.3
12.4
12.4
12.5
12.5
12.6
12.6
12.7
12.7
12.8
12.8
12.9
12.9
13
13
13.1
13.1
13.2
13.2
13.3
13.3
13.4
13.4
13.5
13.5
13.6
13.6
13.7
13.7
13.8
13.8
13.9
13.9
14
14
14.1
14.1
14.2
14.2
14.3
14.3
14.4
14.4
14.5
14.5
14.6
14.6
14.7
14.7
14.8
14.8
14.9
14.9
15
15
15.1
15.1
15.2
15.2
15.3
15.3
15.4
15.4
15.5
15.5
15.6
15.6
15.7
15.7
15.8
15.8
15.9
15.9
16

-63.8
-63.8
-63.8
-63.8
-63.8
-63.9
-64
-63.9
-63.8
-63.9
-63.8
-63.9
-63.8
-63.9
-64
-64
-64
-64
-64
-64
-63.9
-64
-63.9
-63.9
-64
-64
-63.8
-63.7
-63.6
-63.7
-63.9
-63.6
-63.4
-63.5
-63.1
-63.3
-63.2
-63.2
-63.2
-63.1
-63
-62.8
-62.6
-62.8
-62.8
-62.7
-62.5
-62.4
-62.3
-62.3
-62.1
-62.2
-61.8
-62
-62.1
-61.9
-61.8
-61.7
-61.5
-61.5
-61.5
-61.4
-61.3
-61.3
-61
-61.1
-60.9
-60.8
-60.9
-60.7
-60.7
-60.6
-60.6
-60.6
-60.4
-60.4
-60.4
-60.2
-60.1
-60.2
-60.1
-59.9
-59.9
-59.8
-59.8
-59.6
-59.7
-59.5
-59.4
-59.4
-59.3
-59.2
-59.1
-59
-59
-59
-59
-58.8
-58.8
-58.8
-58.5
-58.4
-58.3
-58.2
-58
-57.9
-57.7
-57.8
-57.7
-57.6
-57.4
-57.4
-57.3
-57
-56.9
-56.9
-56.9
-56.8
-56.5
-56.6
-56.2
-56
-56
-55.9
-55.7
-55.5
-55.4
-55.1
-55
-54.9
-54.5
-54.3
-54
-53.7
-53.4
-52.9
-52.4
-51.6
-50.5
-48.4
-44.7
-38.9
-30.7
-20.91
-11.14
-2.9
3.3
6.8
8
7.5
5.9
3.6
0.9
-2
-5.3
-8.7
-12.62
-16.24
-20.43
-24.43
-28.59
-32.7
-36.6
-40.2
-43.7
-46.9
-49.7
-52.4
-54.8
-56.8
-58.8
-60.3
-61.7
-62.8
-63.5
-64.6
-65.1
-65.8
-66.1
-66.4
-66.9
-67.1
-67.3
-67.4
-67.4
-67.6
-67.5
-67.6
-67.7
-67.7
-67.6
-67.6
-67.6
-67.5
-67.3
-67.2
-67.1
-67
-67
-66.9
-66.9
-66.7
-66.6
-66.7
-66.8
-66.7
-66.5
-66.4
-66.4
-66.3
-66.3
-66.1
-66
-65.9
-65.9
-65.6
-65.7
-65.7
-65.6
-65.3
-65.4
-65.2
-65.1
-65
-65.1
-64.9
-64.8
-65
-65
-64.9
-64.8
-65
-64.9
-64.9
-65.1
-64.9
-65.1
-65
-64.9
-65
-65
-65
-65
-65.3
-65
-65.1
-65
-65
-65.2
-65.1
-65.2
-65.1
-65.1
-65.3
-65.3
-65.3
-65.3
-65.2
-65.5
-65.3
-65.5
-65.4
-65.3
-65.2
-65.3
-65.1
-65.3
-65.4
-65.4
-65.3
-65.2
-65.2
-65.3
-65.3
-65.4
-65.3
-65.2
-65.4
-65.3
-65.3
-65.3
-65.4
-65.3
-65.4
-65.4
-65.3
-65.3
-65.3
-65.4
-65.3
-65.2
-65.3
-65.4
-65.3
-65.3
-65.3
-65.3
-65.4
-65.3
-65.6
-65.4
-65.4
-65.5
-65.4
-65.4
-65.4
-65.3
-65.5
-65.4
-65.4
-65.4
-65.6
-65.5
-65.4
-65.4
-65.5
-65.5
-65.3
-65.6
-65.5

2
0
16

0
1

1

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