Steady-state Vm distribution of neurons subject to synaptic noise (Rudolph, Destexhe 2005)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:64259
This package simulates synaptic background activity similar to in vivo measurements using a model of fluctuating synaptic conductances, and compares the simulations with analytic estimates. The steady-state membrane potential (Vm) distribution is calculated numerically and compared with the "extended" analytic expression provided in the reference (see this paper for details).
Reference:
1 . Rudolph M, Destexhe A (2005) An extended analytic expression for the membrane potential distribution of conductance-based synaptic noise. Neural Comput 17:2301-15 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Synapse;
Brain Region(s)/Organism:
Cell Type(s): Neocortex L5/6 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s): GabaA; AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Synaptic noise;
Implementer(s): Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell; GabaA; AMPA;
/
NCnote
readme.txt
Gfluct.mod
demo.hoc
mosinit.hoc *
                            
load_file("nrngui.hoc")
load_file("demo.hoc")

Loading data, please wait...