This a conductance-based model of a rod photoreceptor cell based on other modeling works
(Barnes and Hille 1989 and Publio et al. 2006 and Kourennyi and Liu et al. 2004 ). In this
model four types of ionic channels identified in the inner segment of the rod: nonselective cation channel (h), delayed rectifying potassium channel (Kv), noninactivating potassium channel (Kx) and calcium channel (Ca) was used.
The model accurately reproduces the rod response when stimulated with a simulated photocurrent signal. We can show the effect of nonselective cation channel. The absence of this channel cause increasing the peak amplitude and the time to
reach the peak of voltage response and absence of transient mode in this response.
Barnes S, Hille B (1989) Ionic channels of the inner segment of tiger salamander cone photoreceptors. J Gen Physiol 94:719-43 [PubMed]
Kourennyi DE, Liu XD, Hart J, Mahmud F, Baldridge WH, Barnes S (2004) Reciprocal modulation of calcium dynamics at rod and cone photoreceptor synapses by nitric oxide. J Neurophysiol 92:477-83 [PubMed]
Liu XD, Kourennyi DE (2004) Effects of tetraethylammonium on Kx channels and simulated light response in rod photoreceptors. Ann Biomed Eng 32:1428-42 [PubMed]
Publio R, Oliveira RF, Roque AC (2006) A realistic model of rod photoreceptor for use in a retina network model Neurocomputing 69:1020-1024