Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Spontaneous calcium oscillations in astrocytes (Lavrentovich and Hemkin 2008)
 
Download zip file
Help downloading and running models
Model Information
Model File
Citations
Accession:
112547
" ... We propose here a mathematical model of how spontaneous Ca2+ oscillations arise in astrocytes. This model uses the calcium-induced calcium release and inositol cross-coupling mechanisms coupled with a receptor-independent method for producing inositol (1,4,5)-trisphosphate as the heart of the model. By computationally mimicking experimental constraints we have found that this model provides results that are qualitatively similar to experiment."
Reference:
1 .
Lavrentovich M, Hemkin S (2008) A mathematical model of spontaneous calcium(II) oscillations in astrocytes.
J Theor Biol
251
:553-60
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Electrogenic pump;
Glia;
Brain Region(s)/Organism:
Cell Type(s):
Astrocyte;
Channel(s):
Gap Junctions:
Receptor(s):
IP3;
Gene(s):
Transmitter(s):
Ions;
Simulation Environment:
XPP;
Model Concept(s):
Oscillations;
Simplified Models;
Signaling pathways;
Calcium dynamics;
Calcium waves;
Implementer(s):
Wu, Sheng-Nan [snwu at mail.ncku.edu.tw];
Search NeuronDB
for information about:
IP3
;
Ions
;
Download the displayed file
/
Glia-Ca
readme.html
Astro-Ca.pdf
Ca-Oscil-Astrocyte.ode
Glia-Oscill.JPG
Loading data, please wait...