In this review some of the recent work carried out in our laboratory concerning the functional
role of GABAergic signalling at immature mossy fibres (MF)-CA3 principal cell synapses has
been highlighted. To compare the relative strength of CA3 pyramidal cell
output in relation to their MF glutamatergic or GABAergic inputs in postnatal
development, a realistic model was constructed taking into account the different
biophysical properties of these synapses.
Safiulina VF, Caiati MD, Sivakumaran S, Bisson G, Migliore M, Cherubini E (2010) Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus. Front Synaptic Neurosci 2:1 [PubMed]