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A model of unitary responses from A/C and PP synapses in CA3 pyramidal cells (Baker et al. 2010)
 
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Accession:
137259
The model was used to reproduce experimentally determined mean synaptic response characteristics of unitary AMPA and NMDA synaptic stimulations in CA3 pyramidal cells with the objective of inferring the most likely response properties of the corresponding types of synapses. The model is primarily concerned with passive cells, but models of active dendrites are included.
Reference:
1 .
Baker JL, Perez-Rosello T, Migliore M, Barrionuevo G, Ascoli GA (2011) A computer model of unitary responses from associational/commissural and perforant path synapses in hippocampal CA3 pyramidal cells.
J Comput Neurosci
31
:137-58
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Synapse;
Dendrite;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA3 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
AMPA;
NMDA;
Gene(s):
Transmitter(s):
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Implementer(s):
Baker, John L [jbakerb at gmu.edu];
Search NeuronDB
for information about:
Hippocampus CA3 pyramidal GLU cell
;
AMPA
;
NMDA
;
Glutamate
;
/
ca3-synresp
readme.html
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Amyloid beta (IA block) effects on a model CA1 pyramidal cell (Morse et al. 2010)
CA1 pyramidal neuron: effects of R213Q and R312W Kv7.2 mutations (Miceli et al. 2013)
CA3 pyramidal neuron (Safiulina et al. 2010)
CA3 pyramidal neuron: firing properties (Hemond et al. 2008)
Channel density variability among CA1 neurons (Migliore et al. 2018)
Circadian rhythmicity shapes astrocyte morphology and neuronal function in CA1 (McCauley et al 2020)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Firing patterns of CA3 hippocampal neurons (Soldado-Magraner et al. 2019)
can2.mod
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Other models using can2.mod:
Amyloid beta (IA block) effects on a model CA1 pyramidal cell (Morse et al. 2010)
CA3 pyramidal neuron (Safiulina et al. 2010)
CA3 pyramidal neuron: firing properties (Hemond et al. 2008)
Channel density variability among CA1 neurons (Migliore et al. 2018)
Circadian rhythmicity shapes astrocyte morphology and neuronal function in CA1 (McCauley et al 2020)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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Long time windows from theta modulated inhib. in entorhinal–hippo. loop (Cutsuridis & Poirazi 2015)
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Amyloid beta (IA block) effects on a model CA1 pyramidal cell (Morse et al. 2010)
CA3 pyramidal neuron (Safiulina et al. 2010)
CA3 pyramidal neuron: firing properties (Hemond et al. 2008)
Channel density variability among CA1 neurons (Migliore et al. 2018)
Circadian rhythmicity shapes astrocyte morphology and neuronal function in CA1 (McCauley et al 2020)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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CA1 pyramidal neurons: effects of a Kv7.2 mutation (Miceli et al. 2009)
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Channel density variability among CA1 neurons (Migliore et al. 2018)
Circadian rhythmicity shapes astrocyte morphology and neuronal function in CA1 (McCauley et al 2020)
Computational neuropharmacology of CA1 pyramidal neuron (Ferrante et al. 2008)
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Early-onset epileptic encephalopathy (Miceli et al. 2015)
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Effects of electric fields on cognitive functions (Migliore et al 2016)
Feedforward inhibition in pyramidal cells (Ferrante & Ascoli 2015)
Functional impact of dendritic branch point morphology (Ferrante et al., 2013)
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CA1 pyramidal neurons: effects of Kv7 (M-) channels on synaptic integration (Shah et al. 2011)
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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ama-c30573.CNG.hoc
ama-c31162.CNG.hoc
ama-c60361.CNG.hoc
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ama-c73164.CNG.hoc
ama-c81463.CNG.hoc
axon-common.hoc
bar-cell1zr.CNG.hoc
bar-cell2zr.CNG.hoc
bar-cell3zr.CNG.hoc
bar-cell4zr.CNG.hoc
bar-cell5zr.CNG.hoc
bar-cell6zr.CNG.hoc
bar-cell7zr.CNG.hoc
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demo.hoc
demo.png
demo.ses
demo-fig2a-raw-data.csv
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Other models using demo-fig2a-raw-time.csv:
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demo-fig2a-smoothed-data.csv
demo-fig2a-smoothed-time.csv
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Other models using demo-fig2a-smoothed-time.csv:
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out-vc-ampar-c31162-ad67-022.csv
out-vc-ampar-c62563-ad2-01667.csv
out-vc-ampar-c62563-ad54-054.csv
out-vc-fastampar-c62563-ad2-01667.csv
out-vc-nmdar-c81463-ad87-082.csv
out-vc-nmdar-l51-ad7-036.csv
params-by-fig.csv
synresp.hoc
synresp-c30573.hoc
synresp-c31162.hoc
synresp-c60361.hoc
synresp-c62563.hoc
synresp-c73164.hoc
synresp-c81463.hoc
synresp-cell1zr.hoc
synresp-cell2zr.hoc
synresp-cell3zr.hoc
synresp-cell4zr.hoc
synresp-cell5zr.hoc
synresp-cell6zr.hoc
synresp-cell7zr.hoc
synresp-cell8zr.hoc
synresp-l24b.hoc
synresp-l51.hoc
synresp-l56a.hoc
tur-l24b.CNG.hoc
tur-l51.CNG.hoc
tur-l56a.CNG.hoc
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