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Prosthetic electrostimulation for information flow repair in a neocortical simulation (Kerr 2012)
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This model is an extension of a model (<a href="http://senselab.med.yale.edu/ModelDB/ShowModel.asp?model=138379">138379</a>) recently published in Frontiers in Computational Neuroscience. This model consists of 4700 event-driven, rule-based neurons, wired according to anatomical data, and driven by both white-noise synaptic inputs and a sensory signal recorded from a rat thalamus. Its purpose is to explore the effects of cortical damage, along with the repair of this damage via a neuroprosthesis.
Kerr CC, Neymotin SA, Chadderdon GL, Fietkiewicz CT, Francis JT, Lytton WW (2012) Electrostimulation as a prosthesis for repair of information flow in a computer model of neocortex.
IEEE Trans Neural Syst Rehabil Eng
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Neocortex L5/6 pyramidal GLU cell;
Neocortex L2/3 pyramidal GLU cell;
Neocortex V1 interneuron basket PV GABA cell;
Neocortex fast spiking (FS) interneuron;
Neocortex spiny stellate cell;
Deep brain stimulation;
Lytton, William [bill.lytton at downstate.edu];
Neymotin, Sam [Samuel.Neymotin at nki.rfmh.org];
Kerr, Cliff [cliffk at neurosim.downstate.edu];
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Neocortex L5/6 pyramidal GLU cell
Neocortex L2/3 pyramidal GLU cell
Neocortex V1 interneuron basket PV GABA cell
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