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Layer V PFC pyramidal neuron used to study persistent activity (Sidiropoulou & Poirazi 2012)
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"... Here, we use a compartmental modeling approach to search for discriminatory features in the properties of incoming stimuli to a PFC pyramidal neuron and/or its response that signal which of these stimuli will result in persistent activity emergence. Furthermore, we use our modeling approach to study cell-type specific differences in persistent activity properties, via implementing a regular spiking (RS) and an intrinsic bursting (IB) model neuron. ... Collectively, our results pinpoint to specific features of the neuronal response to a given stimulus that code for its ability to induce persistent activity and predict differential roles of RS and IB neurons in persistent activity expression. "
Sidiropoulou K, Poirazi P (2012) Predictive features of persistent activity emergence in regular spiking and intrinsic bursting model neurons.
PLoS Comput Biol
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Neuron or other electrically excitable cell;
Neocortex L5/6 pyramidal GLU cell;
I L high threshold;
Detailed Neuronal Models;
Sidiropoulou, Kyriaki [sidirop at imbb.forth.gr];
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Neocortex L5/6 pyramidal GLU cell
I L high threshold
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