Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Half-center oscillator database of leech heart interneuron model (Doloc-Mihu & Calabrese 2011)
Help downloading and running models
Model Information
Model File
Citations
Accession:
144518
We have created a database (HCO-db) of instances of a half-center oscillator computational model [Hill et al., 2001] for analyzing how neuronal parameters influence network activity. We systematically explored the parameter space of about 10.4 million simulated HCO instances and corresponding isolated neuron model simulations obtained by varying a set of selected parameters (maximal conductance of intrinsic and synaptic currents) in all combinations using a brute-force approach. We classified these HCO instances by their activity characteristics into identifiable groups. We built an efficient relational database table (HCO-db) with the resulting instances characteristics.
Reference:
1 .
Doloc-Mihu A, Calabrese RL (2011) A database of computational models of a half-center oscillator for analyzing how neuronal parameters influence network activity.
J Biol Phys
37
:263-83
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Leech;
Cell Type(s):
Leech heart interneuron;
Channel(s):
I Na,p;
I Na,t;
I K;
I h;
I Calcium;
I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
MySQL (web link to model);
Model Concept(s):
Activity Patterns;
Bursting;
Oscillations;
Invertebrate;
Implementer(s):
Doloc-Mihu, Anca [adolocm at emory.edu];
Search NeuronDB
for information about:
I Na,p
;
I Na,t
;
I K
;
I h
;
I Calcium
;
I Potassium
;
(located via links below)
Loading data, please wait...