Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Model of arrhythmias in a cardiac cells network (Casaleggio et al. 2014)
Download zip file
Help downloading and running models
" ... Here we explore the possible processes leading to the occasional onset and termination of the (usually) non-fatal arrhythmias widely observed in the heart. Using a computational model of a two-dimensional network of cardiac cells, we tested the hypothesis that an ischemia alters the properties of the gap junctions inside the ischemic area. ... In conclusion, our model strongly supports the hypothesis that non-fatal arrhythmias can develop from post-ischemic alteration of the electrical connectivity in a relatively small area of the cardiac cell network, and suggests experimentally testable predictions on their possible treatments."
Casaleggio A, Hines ML, Migliore M (2014) Computational model of erratic arrhythmias in a cardiac cell network: the role of gap junctions.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Cardiac ventricular cell;
Spatio-temporal Activity Patterns;
Detailed Neuronal Models;
Hines, Michael [Michael.Hines at Yale.edu];
Migliore, Michele [Michele.Migliore at Yale.edu];
for information about:
File not selected
<- Select file from this column.
Loading data, please wait...