Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
PreBotzinger Complex inspiratory neuron with NaP and CAN currents (Park and Rubin 2013)
Download zip file
Help downloading and running models
We have built on earlier models to develop a single-compartment Hodgkin-Huxley type model incorporating NaP and CAN currents, both of which can play important roles in bursting of inspiratory neurons in the PreBotzinger Complex of the mammalian respiratory brain stem. The model tracks the evolution of membrane potential, related (in)activation variables, calcium concentration, and available fraction of IP3 channels. The model can produce several types of bursting, presented and analyzed from a dynamical systems perspective in our paper.
Park C, Rubin JE (2013) Cooperation of intrinsic bursting and calcium oscillations underlying activity patterns of model pre-Bötzinger complex neurons.
J Comput Neurosci
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Respiratory column neuron;
PreBotzinger complex neuron;
Rubin, Jonathan E [jonrubin at pitt.edu];
Park, Choongseok [cpark at ncat.edu];
for information about:
File not selected
<- Select file from this column.
Loading data, please wait...