Temperature-Dependent Pyloric Pacemaker Kernel (Caplan JS et al., 2014)

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Accession:152636
"... Here we demonstrate that biophysical models of channel noise can give rise to two kinds of recently discovered stochastic facilitation effects in a Hodgkin-Huxley-like model of auditory brainstem neurons. The first, known as slope-based stochastic resonance (SBSR), enables phasic neurons to emit action potentials that can encode the slope of inputs that vary slowly relative to key time constants in the model. The second, known as inverse stochastic resonance (ISR), occurs in tonically firing neurons when small levels of noise inhibit tonic firing and replace it with burstlike dynamics. ... our results show that possible associated computational benefits may occur due to channel noise in neurons of the auditory brainstem. ... "
Reference:
1 . Caplan JS, Williams AH, Marder E (2014) Many parameter sets in a multicompartment model oscillator are robust to temperature perturbations. J Neurosci 34:4963-75 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Stomatogastric ganglion (STG) pyloric dilator (PD) neuron; Stomatogastric ganglion (STG) pyloric neuron;
Channel(s): I A; I K,leak; I h; I K,Ca; I Sodium; I Calcium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program;
Model Concept(s): Bursting; Parameter sensitivity; Temperature; Audition;
Implementer(s): Caplan, Jonathan S [joncaplan at gmail.com];
Search NeuronDB for information about:  I A; I K,leak; I h; I K,Ca; I Sodium; I Calcium;
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CaplanEtAl2014
.hg
readme.txt
call_model.cpp
g_maxes.txt
model.cpp
model.h
                            
412.72	23.609	92.765	14.07	2.6022	0.1061	3140.6	3686.3	180.73	667.35	1099	82.305	29.923	77.029	5.6932	0.12909	2660	248.91	41.84	0
355.49	71.253	86.892	10.904	1.4156	0.036018	1903.5	9527.5	310.62	171.99	1582.8	260.74	14.933	62.991	7.2169	0.13924	1081.1	171	38.112	0
508.2	5.7604	77.159	16.814	4.7129	0.024495	3005.1	3090.9	50.497	551.69	1461.3	207.05	38.2	43.167	0.37758	0.31325	1023.9	405.53	78.717	0
446.89	19.444	84.658	0.87369	0.023004	0.10645	2644	10913	337.17	859.7	1839.5	77.218	1.1742	113.14	7.2664	0.035045	2669.1	378.99	26.893	0
426.94	39.732	44.078	14.854	2.9285	0.040302	2102.3	5472.9	114.75	17.69	1327.4	42.142	16.428	100.18	6.5393	0.19716	2946.3	489.41	55.417	0
345.41	13.209	50.319	8.4566	0.43274	0.028872	1169.2	5319.2	87.277	92.885	2182.5	28.656	7.7725	60.453	5.0803	0.29256	2107.7	46.806	15.788	0

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