Single cell model with variable ion concentrations and Na+/K+ ATPase (Krishnan et al. 2015)

 Download zip file 
Help downloading and running models
This is a single cell model with variable intra and extra cellular ion concentrations for Na+, K+ and Cl- ions. This model also incorporates both the electrogenic and ionic concentration effects of the Na+/K+ pump. The program in this archive will run under CONTENT software to generate various bifurcation plots.
1 . Krishnan GP, Filatov G, Shilnikov A, Bazhenov M (2015) Electrogenic properties of the Na?/K? ATPase control transitions between normal and pathological brain states. J Neurophysiol 113:3356-74 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Neocortex L5/6 pyramidal GLU cell;
Gap Junctions:
Simulation Environment: CONTENT;
Model Concept(s): Action Potentials;
Implementer(s): Bazhenov, Maxim [Bazhenov at];
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell;
This is the readme for the code associated with the paper:

Electrogenic properties of the Na+/K+ ATPase controls transitions
between normal and pathological brain states Giri P Krishnan, Gregory
Filatov, Andrey Shilnikov, Maxim Bazhenov January 14, 2015

DOI: 10.1152/jn.00460.2014

This code was supplied by Giri Prashanth Krishnan and runs with the
CONTENT package.

Loading data, please wait...