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Spikelet generation and AP initiation in a L5 neocortical pyr neuron (Michalikova et al. 2017) Fig 1
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Accession:
206398
The article by Michalikova et al. (2017) explores the generation of spikelets in cortical pyramidal neurons. The model cell, adapted from Hu et al. (2009), is a layer V pyramidal neuron. The cell is stimulated by fluctuating synaptic inputs and generates somatic APs and spikelets in response. The spikelets are initiated as APs at the AIS that do not activate the soma.
Reference:
1 .
Michalikova M, Remme MW, Kempter R (2017) Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma.
PLoS Comput Biol
13
:e1005237
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Axon;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Channel(s):
I Na,t;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Python;
Model Concept(s):
Action Potentials;
Electrotonus;
Action Potential Initiation;
Axonal Action Potentials;
Implementer(s):
Michalikova, Martina [tinka.michalikova at gmail.com];
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
I Na,t
;
Download the displayed file
/
MichalikovaEtAl2016Fig1
morphology
Readme.html
ca.mod
*
Other models using ca.mod:
AP initiation, propagation, and cortical invasion in a Layer 5 pyramidal cell (Anderson et 2018)
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)
cad.mod
*
Other models using cad.mod:
AP initiation, propagation, and cortical invasion in a Layer 5 pyramidal cell (Anderson et 2018)
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)
Gfluct.mod
kca.mod
*
Other models using kca.mod:
AP initiation, propagation, and cortical invasion in a Layer 5 pyramidal cell (Anderson et 2018)
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)
km.mod
*
Other models using km.mod:
AP initiation, propagation, and cortical invasion in a Layer 5 pyramidal cell (Anderson et 2018)
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)
kv.mod
*
Other models using kv.mod:
AP initiation, propagation, and cortical invasion in a Layer 5 pyramidal cell (Anderson et 2018)
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)
na.mod
*
Other models using na.mod:
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
na12.mod
*
Other models using na12.mod:
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)
na16.mod
*
Other models using na16.mod:
Action Potential initiation and backpropagation in Neocortical L5 Pyramidal Neuron (Hu et al. 2009)
Gfluct_session.ses
mosinit.hoc
P_DensityMech.hoc
screenshot.png
Spikelets_Main.hoc
load_file("nrngui.hoc") load_file("Spikelets_Main.hoc")
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