Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Model of CA1 activity during working memory task (Spera et al. 2016)
 
Download zip file
Help downloading and running models
Model Information
Model File
Citations
Accession:
223962
"The cellular processes underlying individual differences in the Woring Memory Capacity (WMC) of humans are essentially unknown. Psychological experiments suggest that subjects with lower working memory capacity (LWMC), with respect to subjects with higher capacity (HWMC), take more time to recall items from a list because they search through a larger set of items and are much more susceptible to interference during retrieval. ... In this paper, we investigate the possible underlying mechanisms at the single neuron level by using a computational model of hippocampal CA1 pyramidal neurons, which have been suggested to be deeply involved in the recognition of specific items. ..."
Reference:
1 .
Spera E, Migliore M, Unsworth N, Tegolo D (2016) On the cellular mechanisms underlying working memory capacity in humans
Neural Network World
4
:335-359
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Synapse;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Working memory;
Implementer(s):
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
/
SperaEtAl2016
File not selected
<- Select file from this column.
Loading data, please wait...