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CA1 pyr cell: Inhibitory modulation of spatial selectivity+phase precession (Grienberger et al 2017)
 
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Accession:
225080
Spatially uniform synaptic inhibition enhances spatial selectivity and temporal coding in CA1 place cells by suppressing broad out-of-field excitation.
Reference:
1 .
Grienberger C, Milstein AD, Bittner KC, Romani S, Magee JC (2017) Inhibitory suppression of heterogeneously tuned excitation enhances spatial coding in CA1 place cells.
Nat Neurosci
20
:417-426
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Realistic Network;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
NMDA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Python;
Model Concept(s):
Active Dendrites;
Detailed Neuronal Models;
Place cell/field;
Synaptic Integration;
Short-term Synaptic Plasticity;
Spatial Navigation;
Feature selectivity;
Implementer(s):
Milstein, Aaron D. [aaronmil at stanford.edu];
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
NMDA
;
Download the displayed file
/
GrienbergerEtAl2017
morphologies
EB1-early-bifurcation.swc
EB1-early-bifurcation.tiff
EB2-late-bifurcation.swc
*
Other models using EB2-late-bifurcation.swc:
CA1 pyramidal neuron: Persistent Na current mediates steep synaptic amplification (Hsu et al 2018)
EB2-late-bifurcation.tiff
*
Other models using EB2-late-bifurcation.tiff:
CA1 pyramidal neuron: Persistent Na current mediates steep synaptic amplification (Hsu et al 2018)
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