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Mechanisms underlying different onset patterns of focal seizures (Wang Y et al 2017)
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Model Information
Model File
Citations
Accession:
226074
"Focal seizures are episodes of pathological brain activity that appear to arise from a localised area of the brain. The onset patterns of focal seizure activity have been studied intensively, and they have largely been distinguished into two types { low amplitude fast oscillations (LAF), or high amplitude spikes (HAS). Here we explore whether these two patterns arise from fundamentally different mechanisms. Here, we use a previously established computational model of neocortical tissue, and validate it as an adequate model using clinical recordings of focal seizures. We then reproduce the two onset patterns in their most defining properties and investigate the possible mechanisms underlying the different focal seizure onset patterns in the model. ..."
Reference:
1 .
Wang Y, Trevelyan AJ, Valentin A, Alarcon G, Taylor PN, Kaiser M (2017) Mechanisms underlying different onset patterns of focal seizures
PLoS
13(5)
:e1005475
Model Information
(Click on a link to find other models with that property)
Model Type:
Neural mass;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
MATLAB;
Model Concept(s):
Epilepsy;
Beta oscillations;
Gamma oscillations;
Oscillations;
Activity Patterns;
Spatio-temporal Activity Patterns;
Implementer(s):
Wang, Yujiang [yujiang.wang at newcastle.ac.uk];
Download the displayed file
/
WangYetAl2017
lib
ConnLocGaussian.m
*
Other models using ConnLocGaussian.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
ConnPatchyRemOverlap.m
*
Other models using ConnPatchyRemOverlap.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
convolve2.m
*
Other models using convolve2.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
distSheet.m
*
Other models using distSheet.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
distTorus.m
*
Other models using distTorus.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
Mechanisms underlying different onset patterns of focal seizures (Wang Y et al 2017)
exindex.m
*
Other models using exindex.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
FilterEEG.m
Gaussian.m
*
Other models using Gaussian.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
GaussianLocConnFunc.m
generatePatchesOverlap.m
*
Other models using generatePatchesOverlap.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
getDelayMatrix.m
getDelayMatrixserial.m
getNoise.m
getParam.m
*
Other models using getParam.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
getParamDelay.m
KLDiv.m
makeCellCluster.m
*
Other models using makeCellCluster.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
makeCellClusterToroidal.m
*
Other models using makeCellClusterToroidal.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
MayColourMap.mat
*
Other models using MayColourMap.mat:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
meanMacroCol.m
*
Other models using meanMacroCol.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
ODEsheet.m
ODEsheetStim.m
plotVideo.m
runSheet.m
*
Other models using runSheet.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
runSheetDelay.m
*
Other models using runSheetDelay.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
runSheetDelayRamp.m
runSheetPRamp.m
*
Other models using runSheetPRamp.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
Sigm.m
*
Other models using Sigm.m:
A cortical sheet mesoscopic model for investigating focal seizure onset dynamics (Wang et al. 2014)
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