Stochastic layer V pyramidal neuron: interpulse interval coding and noise (Singh & Levy 2017)

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Accession:237594
Layer V pyramidal neuron with stochastic Na channels. Supports evidence for interpulse interval coding and has very detailed AIS with Nav1.2 and Nav1.6 channels.
Reference:
1 . Singh C, Levy WB (2017) A consensus layer V pyramidal neuron can sustain interpulse-interval coding. PLoS One 12:e0180839 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Neocortex;
Cell Type(s): Neocortex L5/6 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation;
Implementer(s): Singh, Chandan [chandan_singh at berkeley.edu];
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell;
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stochastic_layer5_pyramidal
mechanism
ca.mod *
cad.mod *
gabaa.mod *
kca.mod *
km.mod *
kv.mod *
n12_stoch.mod
na.mod
na_stoch.mod
na12.mod *
na16.mod
na16_stoch.mod
run_act.hoc
                            
cmd_trial_num = 0
trials_per_sweep = 1000
sweep = int(cmd_trial_num/trials_per_sweep) + 1
strdef folder,stoch_str,v_str,cmd_str,chans_str,v_str

//////////// normal /////////////
tstop = 50+50      // ms
stoch = 1           // 1 for stochastic
intensity = 1   // nA
dur = tstop
gamma = 10e-12 // set pS/channel

v_str = "data/out.txt"
chans_str = "data/chans.txt"

// constant
del = 50            // delay
dt = 0.01 // ms
soma_cm = .9

// output
stoch_str="det"
if(stoch==1){
    stoch_str="stoch"
}
printf("intensity: %f",intensity)

// run
chdir("../")
load_file("main.hoc")

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