/*--------------------------------------------------------------
TEMPLATE FILE FOR DEFINING CORTICAL PYRAMIDAL CELLS
---------------------------------------------------
SIMPLIFIED NEURONS:
- one compartment model and currents derived from:
McCormick, D.A., Wang, Z. and Huguenard, J. Neurotransmitter
control of neocortical neuronal activity and excitability.
Cerebral Cortex 3: 387-398, 1993.
- passive
- HH: Traub
- IM: m format
Alain Destexhe, Laval University, 1995
--------------------------------------------------------------*/
begintemplate sPY // create a new template object
public soma,all
objref all
create soma[1]
proc init() { local v_potassium, v_sodium
v_potassium = -100 // potassium reversal potential
v_sodium = 50 // sodium reversal potential
soma {
Ra = 100 // geometry
nseg = 1
diam = 96
L = 96 // so that area is about 29000 um2
cm = 1
insert pas // leak current
e_pas = -70
g_pas = 0.0001 // Rin = 34 Meg
// conversion with McC units:
// g(S/cm2) = g(nS)*1e-9/29000e-8
// = g(nS) * 3.45e-6
insert hh2cx // Hodgin-Huxley INa and IK
ek = v_potassium
ena = v_sodium
vtraub_hh2cx = -55 // Resting Vm, BJ was -55
gnabar_hh2cx = 0.05 // McCormick=15 muS, thal was 0.09
gkbar_hh2cx = 0.005 // spike duration of pyr cells
insert im // M current
taumax_im = 1000
gkbar_im = 7e-5 // Diego's IM (copyrighted)
// insert iahp
// alpha_iahp = 1.25e9
// beta_iahp = 0.001
// gkbar_iahp = 1.7e-5 // McCormick=5 nS
// insert cad // calcium decay
// depth_cad = 1 // McCormick= 0.1 um
// taur_cad = 5 // McCormick=1 ms !!!
// cainf_cad = 2.4e-4 // McCormick=0
// kt_cad = 0 // no pump
}
all = new SectionList()
soma all.append()
}
endtemplate sPY
| 
