Thalamocortical loop with delay for investigation of absence epilepsy (Liu et al 2019)

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Accession:247704
Conductance based network model of one thalamic reticular neuron, one thalamic pyramidal neuron and one cortical pyramidal neuron. Used to show that large delay in the corticothalamic connection can lead to multistability.
Reference:
1 . Liu Y, Milton J, Campbell SA (2019) Outgrowing seizures in Childhood Absence Epilepsy: time delays and bistability. J Comput Neurosci [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Thalamus;
Cell Type(s): Thalamus reticular nucleus GABA cell;
Channel(s): I T low threshold; I M; I h; I Sodium; I Potassium;
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: XPP;
Model Concept(s):
Implementer(s): Liu, Yu ; Campbell, Sue Ann [sacampbell at uwaterloo.ca];
Search NeuronDB for information about:  Thalamus reticular nucleus GABA cell; GabaA; GabaB; AMPA; I T low threshold; I M; I h; I Sodium; I Potassium; Gaba; Glutamate;
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