Factors contribution to GDP-induced [Cl-]i transients (Lombardi et al 2019)

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Accession:253369
This models are used to evaluate which factors influence the GDP (giant depolarizing potential) induced [Cl-]I transients based on a initial model of P. Jedlicka
Reference:
1 . Lombardi A, Jedlicka P, Luhmann HJ, Kilb W (2019) Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration Int J of Mol Sci [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Dendrite; Synapse;
Brain Region(s)/Organism: Mouse; Hippocampus;
Cell Type(s): Hippocampus CA3 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s): GabaA;
Gene(s):
Transmitter(s): Gaba;
Simulation Environment: NEURON;
Model Concept(s): Synaptic Plasticity;
Implementer(s):
Search NeuronDB for information about:  Hippocampus CA3 pyramidal GLU cell; GabaA; Gaba;
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LombardiEtAl2019
Real_Cell_Dynamic_Cl_HCO3_1GDP
cldif_CA3_NKCC1_HCO3.mod *
gabaA_Cl_HCO3.mod *
VDpas.mod *
vecevent.mod *
Cell1_Cl_HCO3_Pas.hoc
Cell1_Cl_HCO3_VDPas.hoc
GDP_Cl_HCO3_All_short.ses *
single_GDP_AMPA_GABA_HCO3_Frontiers.hoc
single_GDP_GABA_HCO3_ForTest.hoc
start_single_GDP_HCO3_Frontiers.hoc
                            
// Start

load_file("nrngui.hoc")
load_file("Cell1_Cl_HCO3_Pas.hoc")
load_file("single_GDP_GABA_HCO3_ForTest.hoc")
load_file("GDP_Cl_HCO3_All_short.ses")

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