Striatal FSI and SPN oscillation model (Chartove et al. 2020)

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Accession:261461
Our model consists of three interconnected populations of single or double compartment Hodgkin-Huxley neurons: a feedforward network of FSIs, and two networks of SPNs (the D1 receptor-expressing "direct pathway" subnetwork and the D2 receptor-expressing "indirect pathway" subnetwork).
Reference:
1 . Chartove JA, McCarthy MM, Pittman-Polletta BR, Kopell NJ (2020) A biophysical model of striatal microcircuits suggests gamma and beta oscillations interleaved at delta/theta frequencies mediate periodicity in motor control PLOS Computational Biology 16:1-30
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Striatum;
Cell Type(s): Neostriatum medium spiny direct pathway GABA cell; Neostriatum medium spiny indirect pathway GABA cell; Neostriatum fast spiking interneuron;
Channel(s): I Potassium; I M;
Gap Junctions: Gap junctions;
Receptor(s): Dopaminergic Receptor;
Gene(s):
Transmitter(s): Dopamine; Gaba;
Simulation Environment: DynaSim;
Model Concept(s): Oscillations; Beta oscillations; Gamma oscillations; Theta oscillations;
Implementer(s): Chartove, Julia A K [chartove at bu dot edu];
Search NeuronDB for information about:  Neostriatum medium spiny direct pathway GABA cell; Neostriatum medium spiny indirect pathway GABA cell; Dopaminergic Receptor; I M; I Potassium; Dopamine; Gaba;
 
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