Systematic integration of data into multi-scale models of mouse primary V1 (Billeh et al 2020)


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Accession:265592
"Highlights • Two network models of the mouse primary visual cortex are developed and released • One uses compartmental-neuron models and the other point-neuron models • The models recapitulate observations from in vivo experimental data • Simulations identify experimentally testable predictions about cortex circuitry"
Reference:
1 . Billeh YN, Cai B, Gratiy SL, Dai K, Iyer R, Gouwens NW, Abbasi-Asl R, Jia X, Siegle JH, Olsen SR, Koch C, Mihalas S, Arkhipov A (2020) Systematic Integration of Structural and Functional Data into Multi-scale Models of Mouse Primary Visual Cortex. Neuron 106:388-403.e18 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Neocortex; Mouse;
Cell Type(s): Neocortex L2/3 pyramidal GLU cell; Neocortex V1 interneuron basket PV GABA cell; Neocortex V1 interneuron chandelier SOM GABA cell; Neocortex V1 L4 stellate GLU cell; Neocortex L5/6 pyramidal GLU cell; Neocortex layer 2-3 interneuron; Neocortex layer 4 interneuron; Neocortex layer 4 pyramidal cell; Neocortex layer 5 interneuron; Neocortex spiking low threshold (LTS) neuron; Neocortex spiking regular (RS) neuron;
Channel(s): I L high threshold; I h; I T low threshold; I M; I K; I Krp; I A; I Na,t; I Na,p; I K,Ca;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON (web link to model); NEST (web link to model);
Model Concept(s): Vision; Simplified Models; Detailed Neuronal Models; Activity Patterns;
Implementer(s):
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell; Neocortex L2/3 pyramidal GLU cell; Neocortex V1 interneuron basket PV GABA cell; Neocortex V1 interneuron chandelier SOM GABA cell; Neocortex V1 L4 stellate GLU cell; I Na,p; I Na,t; I L high threshold; I T low threshold; I A; I K; I M; I h; I K,Ca; I Krp;
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