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Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. 2021)
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Model Information
Model File
Citations
Accession:
266851
We simulated chirp current stimulation in the apical dendrites of 5 biophysically-detailed multi-compartment models of neocortical pyramidal tract neurons and found that a combination of HCN channels and TASK-like channels produced the best fit to experimental measurements of dendritic impedance. We then explored how HCN and TASK-like channels can shape the dendritic impedance as well as the voltage response to synaptic currents.
Reference:
1 .
Kelley C, Dura-Bernal S, Neymotin SA, Antic SD, Carnevale NT, Migliore M, Lytton WW (2021) Effects of Ih and TASK-like shunting current on dendritic impedance in layer 5 pyramidal-tract neurons.
J Neurophysiology
125
:1501-1516
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Neocortex M1 L5B pyramidal pyramidal tract GLU cell;
Channel(s):
I h;
TASK channel;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Python;
NetPyNE;
Model Concept(s):
Impedance;
Implementer(s):
Kelley, Craig;
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
Neocortex M1 L5B pyramidal pyramidal tract GLU cell
;
I h
;
TASK channel
;
/
L5PYR_Resonance-master
models
DuraBernal
cells
cellDensity.pkl
*
Other models using cellDensity.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
cellDensity.py
CT6_reduced_cellParams.pkl
*
Other models using CT6_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
FS3.hoc
*
Other models using FS3.hoc:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT_full_BS1578_cellParams.pkl
*
Other models using IT_full_BS1578_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT_full_BS1579_cellParams.pkl
*
Other models using IT_full_BS1579_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT2_reduced_cellParams.pkl
*
Other models using IT2_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT4_reduced_cellParams.pkl
*
Other models using IT4_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT5A_full_cellParams.pkl
*
Other models using IT5A_full_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT5A_reduced_cellParams.pkl
*
Other models using IT5A_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT5B_full_cellParams.pkl
*
Other models using IT5B_full_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT5B_reduced_cellParams.pkl
*
Other models using IT5B_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
IT6_reduced_cellParams.pkl
*
Other models using IT6_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
ITcell.py
LTS3.hoc
*
Other models using LTS3.hoc:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
popColors.pkl
*
Other models using popColors.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
PT_full_cellParams.pkl
*
Other models using PT_full_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
PT5B_full_cellParams.pkl
PT5B_reduced_cellParams.pkl
*
Other models using PT5B_reduced_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
PTcell.hoc
*
Other models using PTcell.hoc:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
PV_simple_cellParams.pkl
*
Other models using PV_simple_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
SOM_simple_cellParams.pkl
*
Other models using SOM_simple_cellParams.pkl:
Dendritic Impedance in Neocortical L5 PT neurons (Kelley et al. accepted)
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